Integrative metabolic and transcriptomic profiling of prostate cancer tissue containing reactive stroma

Reactive stroma is a tissue feature commonly observed in the tumor microenvironment of prostate cancer and has previously been associated with more aggressive tumors. The aim of this study was to detect differentially expressed genes and metabolites according to reactive stroma content measured on t...

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Bibliographic Details
Published in:	Scientific reports Vol. 8; no. 1; pp. 14269 - 11
Main Authors:	Andersen, Maria K., Rise, Kjersti, Giskeødegård, Guro F., Richardsen, Elin, Bertilsson, Helena, Størkersen, Øystein, Bathen, Tone F., Rye, Morten, Tessem, May-Britt
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 24-09-2018 Nature Publishing Group Nature Research
Subjects:	14/63 140/131 38/39 38/61 38/90 631/337/572 631/45/320 631/67/327 692/4025/1752 692/4028/67/589/466 Cancer surgery Clinical medical disciplines: 750 DNA microarrays Extracellular matrix Gene expression Histopathology Humanities and Social Sciences Klinisk medisinske fag: 750 Magnetic resonance spectroscopy Medical disciplines: 700 Medisinske Fag: 700 Metabolism Metabolites Metabolomics multidisciplinary Oncology: 762 Onkologi: 762 Prostate cancer Prostatectomy Science Science (multidisciplinary) Stroma Tumors VDP Biochemical Recurrence (BCR) Grade Group High Resolution Magic Angle Spinning Stromal Reaction Prostate Cancer Tissue Samples
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