Preparation of designed poly(d,l-lactide)/nanosized hydroxyapatite composite structures by stereolithography

The preparation of scaffolds to facilitate the replacement of damaged tissues and organs by means of tissue engineering has been much investigated. The key properties of the biomaterials used to prepare such scaffolds include biodegradability, biocompatibility and a well-defined three-dimensional 3-...

Full description

Saved in:
Bibliographic Details
Published in:Acta biomaterialia Vol. 9; no. 4; pp. 5989 - 5996
Main Authors: Ronca, A., Ambrosio, L., Grijpma, D.W.
Format: Journal Article
Language:English
Published: England Elsevier Ltd 01-04-2013
Subjects:
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Abstract The preparation of scaffolds to facilitate the replacement of damaged tissues and organs by means of tissue engineering has been much investigated. The key properties of the biomaterials used to prepare such scaffolds include biodegradability, biocompatibility and a well-defined three-dimensional 3-Dpore network structure. In this study a poly(d,l-lactide)/nanosized hydroxyapatite (PDLLA/nano-Hap) composite resin was prepared and used to fabricate composite films and computer designed porous scaffolds by micro-stereolithography, mixing varying quantities of nano-Hap powder and a liquid photoinitiator into a photo-crosslinkable PDLLA-diacrylate resin. The influence of nano-Hap on the rheological and photochemical properties of the resins was investigated, the materials being characterized with respect to their mechanical, thermal and morphological properties after post-preparation curing. In the cured composites stiffness was observed to increase with increasing concentration of nanoparticles. A computer designed construct with a pore network based on the Schwarz architecture was fabricated by stereolithography using PDLLA/nano-Hap composite resins.
AbstractList The key properties of the biomaterials used to prepare scaffolds to facilitate the replacement of damaged tissues and organs by means of tissue engineering include biodegradability, biocompatibility and a well-defined 3-D pore network structure. A poly(D,L-lactide)/nanosized hydroxyapatite (PDLLA/nano-HAp) composite resin was prepared and used to fabricate composite films and computer designed porous scaffolds by micro-stereolithography, mixing varying quantities of nano-HAp powder and a liquid photoinitiator into a photo-crosslinkable PDLLA-diacrylate resin. The influence of nano-HAp on the rheological and photochemical properties of the resins was studied. The materials were characterised with respect to their mechanical, thermal and morphological properties after post-preparation curing. In the cured composites, stiffness increased with increasing concentration of nanoparticles. A computer designed construct with a pore network based on the Schwarz architecture was fabricated by stereolithography using PDLLA/nano-HAp composite resins.
The preparation of scaffolds to facilitate the replacement of damaged tissues and organs by means of tissue engineering has been much investigated. The key properties of the biomaterials used to prepare such scaffolds include biodegradability, biocompatibility and a well-defined three-dimensional 3-Dpore network structure. In this study a poly(D,L-lactide)/nanosized hydroxyapatite (PDLLA/nano-Hap) composite resin was prepared and used to fabricate composite films and computer designed porous scaffolds by micro-stereolithography, mixing varying quantities of nano-Hap powder and a liquid photoinitiator into a photo-crosslinkable PDLLA-diacrylate resin. The influence of nano-Hap on the rheological and photochemical properties of the resins was investigated, the materials being characterized with respect to their mechanical, thermal and morphological properties after post-preparation curing. In the cured composites stiffness was observed to increase with increasing concentration of nanoparticles. A computer designed construct with a pore network based on the Schwarz architecture was fabricated by stereolithography using PDLLA/nano-Hap composite resins.
Author Grijpma, D.W.
Ambrosio, L.
Ronca, A.
Author_xml – sequence: 1
  givenname: A.
  surname: Ronca
  fullname: Ronca, A.
  email: alfredo.ronca@unina.it, alfredoronca82@hotmail.it
  organization: Institute of Composite and Biomedical Materials, National Research Council of Italy, Piazzale Tecchio 80, 80125 Naples, Italy
– sequence: 2
  givenname: L.
  surname: Ambrosio
  fullname: Ambrosio, L.
  organization: Institute of Composite and Biomedical Materials, National Research Council of Italy, Piazzale Tecchio 80, 80125 Naples, Italy
– sequence: 3
  givenname: D.W.
  surname: Grijpma
  fullname: Grijpma, D.W.
  organization: MIRA Institute for Biomedical Technology and Technical Medicine, Department of Polymer Chemistry and Biomaterials, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands
BackLink https://www.ncbi.nlm.nih.gov/pubmed/23232210$$D View this record in MEDLINE/PubMed
BookMark eNqNkdtq3DAQhkVJaA7tG5TWlynUm9HBknxTKKGHQKCFNtdClse7WryWK9ml7tNXqdNchjADM2K-OaD_jBwNYUBCXlHYUKDycr-xbmp82DCgbJMdQDwjp1QrXapK6qOcK8FKBZKekLOU9gBcU6afkxPGszEKp6T_FnG00U4-DEXoihaT3w7YFmPol4v2XV_2eY1v8e3lYIeQ_J9c2y1tDL8XO-a2CQsXDmOu5CxNcXbTHDEVzZJfGDH0ftqFbbTjbnlBjjvbJ3x5H8_J7aePP66-lDdfP19ffbgpnaj1VDoKnZCaKgQm0FGHnUDGFGIjUUpQHVpWO9cAsrYBriyj3ClX8a6mjAt-Ti7WuWMMP2dMkzn45LDv7YBhTobKmnHFBTwB5UILLSvJnoBSoaCuNGRUrKiLIaWInRmjP9i4GArmTj2zN6t65k49kx3-HfP6fsPcHLB9aPovVwberEBng7Hb6JO5_Z4nVAAUtKY8E-9XAvP__vIYTXIeB4etj-gm0wb_-A1_AUS-uYY
CitedBy_id crossref_primary_10_15302_J_ENG_2015015
crossref_primary_10_1111_ijac_14559
crossref_primary_10_1016_j_jmapro_2020_04_076
crossref_primary_10_1557_mrs_2015_3
crossref_primary_10_1080_03639045_2021_1994990
crossref_primary_10_1002_cbin_11613
crossref_primary_10_1016_j_addma_2018_11_021
crossref_primary_10_1016_j_polymer_2016_12_051
crossref_primary_10_1557_s43578_021_00156_y
crossref_primary_10_1016_j_eurpolymj_2022_111806
crossref_primary_10_3390_coatings12101380
crossref_primary_10_1002_jbio_201900106
crossref_primary_10_3390_ma15165724
crossref_primary_10_1016_j_actbio_2018_07_024
crossref_primary_10_2174_1574888X16666210810111754
crossref_primary_10_1002_anbr_202100073
crossref_primary_10_1016_j_actbio_2018_05_010
crossref_primary_10_3390_polym13213825
crossref_primary_10_3390_polym14102119
crossref_primary_10_1080_09205063_2016_1140613
crossref_primary_10_1071_CH15327
crossref_primary_10_3390_mi11121132
crossref_primary_10_1016_j_eurpolymj_2020_110057
crossref_primary_10_3390_ma12060849
crossref_primary_10_1016_j_ceramint_2021_07_053
crossref_primary_10_1088_1748_605X_ab38c6
crossref_primary_10_1002_ange_202016523
crossref_primary_10_1002_smll_201702831
crossref_primary_10_1016_j_injury_2014_02_035
crossref_primary_10_1088_1758_5090_7_4_045009
crossref_primary_10_1016_j_matdes_2016_10_054
crossref_primary_10_1016_j_ceramint_2022_07_047
crossref_primary_10_1088_1758_5090_ad1b20
crossref_primary_10_3390_biomedicines9111553
crossref_primary_10_3389_fmats_2019_00313
crossref_primary_10_1002_pat_3892
crossref_primary_10_1115_1_4026899
crossref_primary_10_3390_nano13040772
crossref_primary_10_1080_09205063_2018_1553105
crossref_primary_10_1142_S2424913020300029
crossref_primary_10_1016_j_pmatsci_2017_08_003
crossref_primary_10_1002_adem_202101543
crossref_primary_10_1016_j_ceramint_2015_08_004
crossref_primary_10_1002_term_2322
crossref_primary_10_1080_17452759_2013_873337
crossref_primary_10_3390_polym15112555
crossref_primary_10_1007_s40964_022_00362_y
crossref_primary_10_1088_2399_7532_ab201f
crossref_primary_10_1002_anie_202016523
crossref_primary_10_1016_j_compositesa_2020_105841
crossref_primary_10_1186_s12938_020_00810_2
crossref_primary_10_1039_D3TB01236K
crossref_primary_10_1002_marc_202000475
crossref_primary_10_1080_14686996_2020_1748520
crossref_primary_10_3390_polym10020212
crossref_primary_10_1016_j_jtice_2018_01_034
crossref_primary_10_1002_mabi_201600290
crossref_primary_10_1002_mame_201800623
crossref_primary_10_3390_polym8060213
crossref_primary_10_1364_OME_4_002032
crossref_primary_10_1002_macp_202200139
crossref_primary_10_1007_s10118_014_1454_5
crossref_primary_10_1016_j_ijpharm_2017_11_065
crossref_primary_10_1177_0021955X14531002
crossref_primary_10_1016_j_jeurceramsoc_2022_07_019
crossref_primary_10_1002_jbm_a_36498
crossref_primary_10_1016_j_apmt_2020_100700
crossref_primary_10_1016_j_colsurfb_2014_07_032
crossref_primary_10_1021_acs_biomac_9b01272
crossref_primary_10_3390_biomedicines10020395
crossref_primary_10_1002_adfm_202003062
crossref_primary_10_1016_j_compscitech_2018_04_001
crossref_primary_10_1080_17434440_2023_2169130
crossref_primary_10_1016_j_jmbbm_2015_03_022
crossref_primary_10_1007_s40145_020_0375_8
crossref_primary_10_3390_mi11010031
crossref_primary_10_1557_mrs_2015_274
crossref_primary_10_1002_pat_6416
crossref_primary_10_1002_adem_202200859
crossref_primary_10_1016_j_jmapro_2021_10_045
crossref_primary_10_1016_j_actbio_2018_11_039
crossref_primary_10_1088_2057_1976_ac21ab
crossref_primary_10_1002_mabi_201800403
crossref_primary_10_1088_1758_5090_aa6553
crossref_primary_10_1177_25165984241228414
crossref_primary_10_1016_j_mattod_2013_11_017
crossref_primary_10_1088_1361_6528_ab767c
crossref_primary_10_1115_1_4044288
crossref_primary_10_1007_s13233_015_3157_3
crossref_primary_10_1016_j_eurpolymj_2020_110223
crossref_primary_10_1007_s12541_018_0073_4
crossref_primary_10_4028_www_scientific_net_AMM_890_113
crossref_primary_10_1007_s10853_024_09925_6
crossref_primary_10_1155_2014_829145
crossref_primary_10_1016_j_matlet_2014_06_055
crossref_primary_10_1177_2280800018764770
crossref_primary_10_3390_molecules25214919
crossref_primary_10_1016_j_jmbbm_2019_103544
crossref_primary_10_1108_RPJ_09_2020_0224
crossref_primary_10_1515_epoly_2020_0046
crossref_primary_10_1016_j_msec_2021_112618
crossref_primary_10_1557_s43578_023_01144_0
crossref_primary_10_3390_gels9020103
crossref_primary_10_1039_C5RA14155A
Cites_doi 10.1089/ten.teb.2010.0171
10.1007/s10439-006-9156-y
10.1002/adfm.200800344
10.1089/ten.2004.10.1316
10.1016/j.biomaterials.2009.03.055
10.1002/jbm.820270404
10.1016/S0890-6955(97)00137-5
10.1016/j.matlet.2006.10.064
10.1016/j.jconrel.2006.04.007
10.1109/TEPM.2002.1000484
10.1016/0142-9612(95)98272-G
10.1016/j.media.2006.06.001
10.1016/S1350-4533(98)00007-1
10.1002/jbm.a.30601
10.1016/S0142-9612(00)00121-6
10.1016/0032-3861(93)90203-M
10.1038/414699a
10.1007/BF00120378
10.1016/j.biomaterials.2003.07.003
10.1002/1527-2648(200008)2:8<493::AID-ADEM493>3.0.CO;2-C
10.1016/j.biomaterials.2010.05.068
10.1155/2012/694194
10.1002/pen.20331
10.1016/j.compscitech.2010.06.015
10.1016/S0934-8832(11)80063-6
10.1016/j.biomaterials.2010.04.050
10.1002/(SICI)1097-4636(19990315)44:4<407::AID-JBM6>3.0.CO;2-T
10.1111/j.1151-2916.1996.tb09022.x
10.1038/nmat1421
10.1016/S0142-9612(01)00283-6
ContentType Journal Article
Copyright 2012 Acta Materialia Inc.
Copyright © 2012 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
Copyright_xml – notice: 2012 Acta Materialia Inc.
– notice: Copyright © 2012 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
DBID FBQ
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7X8
7QO
8FD
FR3
P64
7SR
7TB
7U5
8BQ
F28
JG9
L7M
DOI 10.1016/j.actbio.2012.12.004
DatabaseName AGRIS
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
MEDLINE - Academic
Biotechnology Research Abstracts
Technology Research Database
Engineering Research Database
Biotechnology and BioEngineering Abstracts
Engineered Materials Abstracts
Mechanical & Transportation Engineering Abstracts
Solid State and Superconductivity Abstracts
METADEX
ANTE: Abstracts in New Technology & Engineering
Materials Research Database
Advanced Technologies Database with Aerospace
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
MEDLINE - Academic
Engineering Research Database
Biotechnology Research Abstracts
Technology Research Database
Biotechnology and BioEngineering Abstracts
Materials Research Database
Engineered Materials Abstracts
Mechanical & Transportation Engineering Abstracts
Solid State and Superconductivity Abstracts
Advanced Technologies Database with Aerospace
ANTE: Abstracts in New Technology & Engineering
METADEX
DatabaseTitleList Materials Research Database
MEDLINE - Academic


Engineering Research Database
MEDLINE
Database_xml – sequence: 1
  dbid: ECM
  name: MEDLINE
  url: https://search.ebscohost.com/login.aspx?direct=true&db=cmedm&site=ehost-live
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Engineering
EISSN 1878-7568
EndPage 5996
ExternalDocumentID 10_1016_j_actbio_2012_12_004
23232210
US201500108813
S1742706112005880
Genre Journal Article
GroupedDBID ---
--K
--M
.~1
0R~
1B1
1~.
1~5
23M
4.4
457
4G.
53G
5GY
5VS
7-5
71M
8P~
AABXZ
AACTN
AAEDT
AAEDW
AAEPC
AAIAV
AAIKJ
AAKOC
AALRI
AAOAW
AAQFI
AAXUO
ABFNM
ABGSF
ABJNI
ABMAC
ABNUV
ABUDA
ABXDB
ABXRA
ABYKQ
ACDAQ
ACGFS
ACIWK
ACNNM
ACPRK
ACRLP
ADBBV
ADEWK
ADEZE
ADMUD
ADUVX
AEBSH
AEHWI
AEKER
AENEX
AEZYN
AFKWA
AFRAH
AFRZQ
AFTJW
AFXIZ
AGHFR
AGUBO
AGYEJ
AHPOS
AIEXJ
AIKHN
AITUG
AJBFU
AJOXV
AKURH
ALMA_UNASSIGNED_HOLDINGS
AMFUW
AMRAJ
AXJTR
BKOJK
BLXMC
CS3
DOVZS
EBS
EFJIC
EFLBG
EJD
ENUVR
EO8
EO9
EP2
EP3
F5P
FDB
FEDTE
FIRID
FNPLU
FYGXN
G-Q
GBLVA
HVGLF
HZ~
IHE
J1W
KOM
M41
MAGPM
MO0
N9A
O-L
O9-
OAUVE
OZT
P-8
P-9
P2P
PC.
Q38
RIG
RNS
ROL
RPZ
SDF
SDG
SES
SEW
SPC
SPCBC
SSG
SSM
SSU
SSZ
T5K
~G-
ABPIF
FBQ
AAXKI
AFJKZ
AKRWK
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7X8
7QO
8FD
FR3
P64
7SR
7TB
7U5
8BQ
F28
JG9
L7M
ID FETCH-LOGICAL-c498t-c10f46817e024ec1cef4e227eeb6e6607fea29ccb0e2db037a213c7c53f912343
ISSN 1742-7061
IngestDate Fri Oct 25 11:37:01 EDT 2024
Fri Oct 25 02:09:33 EDT 2024
Fri Oct 25 23:01:35 EDT 2024
Thu Sep 26 19:07:07 EDT 2024
Sat Sep 28 07:51:33 EDT 2024
Wed Dec 27 19:25:58 EST 2023
Fri Feb 23 02:35:03 EST 2024
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 4
Keywords Biodegradable networks
CAD designed scaffold
Nano-composites
Bone tissue engineering
Stereolithography
Language English
License Copyright © 2012 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c498t-c10f46817e024ec1cef4e227eeb6e6607fea29ccb0e2db037a213c7c53f912343
Notes http://dx.doi.org/10.1016/j.actbio.2012.12.004
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
OpenAccessLink https://ris.utwente.nl/ws/files/6445990/preparation.pdf
PMID 23232210
PQID 1314709580
PQPubID 23479
PageCount 8
ParticipantIDs proquest_miscellaneous_1692373404
proquest_miscellaneous_1348486562
proquest_miscellaneous_1314709580
crossref_primary_10_1016_j_actbio_2012_12_004
pubmed_primary_23232210
fao_agris_US201500108813
elsevier_sciencedirect_doi_10_1016_j_actbio_2012_12_004
PublicationCentury 2000
PublicationDate 2013-04-01
PublicationDateYYYYMMDD 2013-04-01
PublicationDate_xml – month: 04
  year: 2013
  text: 2013-04-01
  day: 01
PublicationDecade 2010
PublicationPlace England
PublicationPlace_xml – name: England
PublicationTitle Acta biomaterialia
PublicationTitleAlternate Acta Biomater
PublicationYear 2013
Publisher Elsevier Ltd
Publisher_xml – name: Elsevier Ltd
References Webster, Ahn (b0090) 2007; 103
Verheyen, de Wijn, van Blitterswijk, de Groot, Rozing (b0135) 1993; 27
Guarino, Lewandowska, Bil, Polak, Ambrosio (b0165) 2010; 70
Currey (b0095) 2001; 414
Huec, Schaeverbeke, Clement, Faber, Rebeller (b0015) 1995; 16
Provin, Monneret (b0045) 2002; 25
Griffith, Halloran, Freeform fabrication of ceramics via (b0050) 1996; 79
Lin, Fang, Tseng, Lee (b0140) 2007; 61
Dhariwal, Hunt, Boland (b0055) 2004; 10
Sarasua, Arraiza, Balerdi, Maiza (b0145) 2005; 45
Clarke, Graves, Wong, Triffitt, Francis, Czernuszka (b0115) 1993; 4
Ripamonti, Ma, Reddi (b0010) 1992; 12
Arcaute, Mann, Wicker (b0065) 2006; 34
Gloria, Russo, De Santis, Ambrosio (b0020) 2009; 3
Rho, Kuhn-Spearing, Zioupos (b0110) 1998; 20
Storey, Warren, Allison, Wiggins, Puckett (b0070) 1993; 34
Gurr, Hoffmann, Ehm, Thomann, Kubler, Mulhaupt (b0075) 2008; 18
Rajagopalan, Robb (b0155) 2006; 10
Melchels, Feijen, Grijpma (b0035) 2010; 31
Guarino, Taddei, Di Foggia, Fagnano, Ciapetti, Ambrosio (b0085) 2009; 15
Lu, Mapili, Suhali, Chen, Roy (b0040) 2006; 77A
Hutmacher (b0005) 2000; 21
Ginebra, Traykova, Planell (b0100) 2006; 113
Pham, Gault (b0120) 1998; 38
Du, Cui, Zhu, de Groot (b0105) 1999; 44
Melchels, Feijen, Grijpma (b0060) 2009; 30
Kim, Knowles, Kim (b0080) 2004; 25
Melchels, Bertoldi, Gabbrielli, Velders, Feijen, Grijpma (b0150) 2010; 31
Hollister (b0025) 2005; 4
Kim, Yeatts, Dean, Fisher (b0030) 2010; 16
Bleach, Nazhata, Tanner, Kellomaki, Tormala (b0130) 2002; 23
Shin, Kim, Jeong, Lee, Lee, Lim (b0160) 2012
Doreau, Chaput, Chartier (b0125) 2000; 2
Gurr (10.1016/j.actbio.2012.12.004_b0075) 2008; 18
Dhariwal (10.1016/j.actbio.2012.12.004_b0055) 2004; 10
Rajagopalan (10.1016/j.actbio.2012.12.004_b0155) 2006; 10
Doreau (10.1016/j.actbio.2012.12.004_b0125) 2000; 2
Verheyen (10.1016/j.actbio.2012.12.004_b0135) 1993; 27
Huec (10.1016/j.actbio.2012.12.004_b0015) 1995; 16
Gloria (10.1016/j.actbio.2012.12.004_b0020) 2009; 3
Webster (10.1016/j.actbio.2012.12.004_b0090) 2007; 103
Melchels (10.1016/j.actbio.2012.12.004_b0060) 2009; 30
Griffith (10.1016/j.actbio.2012.12.004_b0050) 1996; 79
Kim (10.1016/j.actbio.2012.12.004_b0080) 2004; 25
Ginebra (10.1016/j.actbio.2012.12.004_b0100) 2006; 113
Kim (10.1016/j.actbio.2012.12.004_b0030) 2010; 16
Pham (10.1016/j.actbio.2012.12.004_b0120) 1998; 38
Lin (10.1016/j.actbio.2012.12.004_b0140) 2007; 61
Arcaute (10.1016/j.actbio.2012.12.004_b0065) 2006; 34
Sarasua (10.1016/j.actbio.2012.12.004_b0145) 2005; 45
Clarke (10.1016/j.actbio.2012.12.004_b0115) 1993; 4
Bleach (10.1016/j.actbio.2012.12.004_b0130) 2002; 23
Rho (10.1016/j.actbio.2012.12.004_b0110) 1998; 20
Melchels (10.1016/j.actbio.2012.12.004_b0035) 2010; 31
Shin (10.1016/j.actbio.2012.12.004_b0160) 2012
Guarino (10.1016/j.actbio.2012.12.004_b0165) 2010; 70
Hollister (10.1016/j.actbio.2012.12.004_b0025) 2005; 4
Lu (10.1016/j.actbio.2012.12.004_b0040) 2006; 77A
Melchels (10.1016/j.actbio.2012.12.004_b0150) 2010; 31
Provin (10.1016/j.actbio.2012.12.004_b0045) 2002; 25
Storey (10.1016/j.actbio.2012.12.004_b0070) 1993; 34
Guarino (10.1016/j.actbio.2012.12.004_b0085) 2009; 15
Ripamonti (10.1016/j.actbio.2012.12.004_b0010) 1992; 12
Hutmacher (10.1016/j.actbio.2012.12.004_b0005) 2000; 21
Currey (10.1016/j.actbio.2012.12.004_b0095) 2001; 414
Du (10.1016/j.actbio.2012.12.004_b0105) 1999; 44
References_xml – volume: 18
  start-page: 2390
  year: 2008
  end-page: 2397
  ident: b0075
  article-title: Acrylic nanocomposite resins for use in stereolithography and structural light modulation based rapid prototyping and rapid manufacturing technologies
  publication-title: Adv Funct Mater
  contributor:
    fullname: Mulhaupt
– volume: 16
  start-page: 523
  year: 2010
  end-page: 539
  ident: b0030
  article-title: Stereolithographic bone scaffold design parameters osteogenic differentiation and signal expression
  publication-title: Tissue Eng B
  contributor:
    fullname: Fisher
– volume: 16
  start-page: 113
  year: 1995
  end-page: 118
  ident: b0015
  article-title: Influence of porosity on the mechanical resistance of hydroxyapatite ceramics under compressive stress
  publication-title: Biomaterials
  contributor:
    fullname: Rebeller
– volume: 77A
  start-page: 396
  year: 2006
  end-page: 405
  ident: b0040
  article-title: A digital micro-mirror device-based system for the microfabrication of complex, spatially patterned tissue engineering scaffolds
  publication-title: J Biomed Mater Res
  contributor:
    fullname: Roy
– volume: 30
  start-page: 3801
  year: 2009
  end-page: 3809
  ident: b0060
  article-title: A poly(
  publication-title: Biomaterials
  contributor:
    fullname: Grijpma
– volume: 61
  start-page: 3009
  year: 2007
  end-page: 3013
  ident: b0140
  article-title: Effects of hydroxyapatite dosage on mechanical and biological behaviors of polylactic acid composite materials
  publication-title: Mater Lett
  contributor:
    fullname: Lee
– volume: 10
  start-page: 1316
  year: 2004
  end-page: 1322
  ident: b0055
  article-title: Rapid prototyping of tissue-engineering constructs, using photopolymerizable hydrogels and stereolithography
  publication-title: Tissue Eng
  contributor:
    fullname: Boland
– volume: 34
  start-page: 4365
  year: 1993
  end-page: 4372
  ident: b0070
  article-title: Synthesis of bioabsorbable network from methacrylate-endcapped polyesters
  publication-title: Polymer
  contributor:
    fullname: Puckett
– volume: 3
  start-page: 141
  year: 2009
  end-page: 152
  ident: b0020
  article-title: 3D fiber deposition technique to make multifunctional and tailor-made scaffolds for tissue engineering applications
  publication-title: J Appl Biomater Bioceramics
  contributor:
    fullname: Ambrosio
– volume: 12
  start-page: 202
  year: 1992
  end-page: 212
  ident: b0010
  article-title: The critical role of geometry of porous hydroxyapatite delivery system of bone by osteogenin, a bone morphogenic protein
  publication-title: Matrix
  contributor:
    fullname: Reddi
– volume: 103
  start-page: 275
  year: 2007
  end-page: 308
  ident: b0090
  article-title: Nanostructured biomaterials for tissue engineering bone
  publication-title: Adv Biochem Eng Biotechnol
  contributor:
    fullname: Ahn
– year: 2012
  ident: b0160
  article-title: Finite element analysis of Schwarz P surface pore geometries for tissue-engineered scaffolds
  publication-title: Math Probl Eng
  contributor:
    fullname: Lim
– volume: 4
  start-page: 107
  year: 1993
  end-page: 110
  ident: b0115
  article-title: Investigation into the formation and mechanical properties of a bioactive material based on collagen and calcium phosphate
  publication-title: J Mater Sci Mater Med
  contributor:
    fullname: Czernuszka
– volume: 21
  start-page: 2529
  year: 2000
  end-page: 2543
  ident: b0005
  article-title: Scaffolds in tissue engineering bone and cartilage
  publication-title: Biomaterials
  contributor:
    fullname: Hutmacher
– volume: 38
  start-page: 1257
  year: 1998
  end-page: 1287
  ident: b0120
  article-title: A comparison of rapid prototyping technologies
  publication-title: Int J Mach Tools Manuf
  contributor:
    fullname: Gault
– volume: 25
  start-page: 59
  year: 2002
  end-page: 63
  ident: b0045
  article-title: Complex ceramic–polymer composite microparts made by microstereolithography
  publication-title: Trans Elect Pack Man
  contributor:
    fullname: Monneret
– volume: 20
  start-page: 92
  year: 1998
  end-page: 102
  ident: b0110
  article-title: Mechanical properties and the hierarchical structure of bone
  publication-title: Med Eng Phys
  contributor:
    fullname: Zioupos
– volume: 25
  start-page: 1279
  year: 2004
  end-page: 1287
  ident: b0080
  article-title: Hydroxyapatite/poly(epsilon caprolactone) composite coatings on hydroxyapatite porous bone scaffold for drug delivery
  publication-title: Biomaterials
  contributor:
    fullname: Kim
– volume: 27
  start-page: 433
  year: 1993
  end-page: 444
  ident: b0135
  article-title: Hydroxylapatite/poly(
  publication-title: J Biomed Mater Res
  contributor:
    fullname: Rozing
– volume: 45
  start-page: 745
  year: 2005
  end-page: 753
  ident: b0145
  article-title: Crystallinity and mechanical properties of optically pure polylactides and their blends
  publication-title: Polym Eng Sci
  contributor:
    fullname: Maiza
– volume: 15
  start-page: 3662
  year: 2009
  end-page: 3670
  ident: b0085
  article-title: Polylactic acid fibre-reinforced polycaprolactone scaffolds for bone tissue engineering
  publication-title: Tissue Eng A
  contributor:
    fullname: Ambrosio
– volume: 414
  start-page: 773
  year: 2001
  end-page: 776
  ident: b0095
  article-title: Biomaterial sacrificial bonds heal bone
  publication-title: Nature
  contributor:
    fullname: Currey
– volume: 23
  start-page: 1579
  year: 2002
  end-page: 1585
  ident: b0130
  article-title: Effect of filler content on mechanical and dynamic mechanical properties of particulate biphasic calcium phosphate–polylactide composites
  publication-title: Biomaterials
  contributor:
    fullname: Tormala
– volume: 34
  start-page: 1429
  year: 2006
  end-page: 1441
  ident: b0065
  article-title: Stereolithography of three-dimensional bioactive poly(ethylene glycol) constructs with encapsulated cells
  publication-title: Ann Biomed Eng
  contributor:
    fullname: Wicker
– volume: 2
  start-page: 493
  year: 2000
  end-page: 496
  ident: b0125
  article-title: Stereolithography for manufacturing ceramic parts
  publication-title: Adv Eng Mater
  contributor:
    fullname: Chartier
– volume: 113
  start-page: 102
  year: 2006
  end-page: 110
  ident: b0100
  article-title: Calcium phosphate cements as bone drug delivery systems: a review
  publication-title: J Control Release
  contributor:
    fullname: Planell
– volume: 4
  start-page: 518
  year: 2005
  end-page: 524
  ident: b0025
  article-title: Porous scaffold design for tissue engineering
  publication-title: Nat Mater
  contributor:
    fullname: Hollister
– volume: 31
  start-page: 6909
  year: 2010
  end-page: 6916
  ident: b0150
  article-title: Mathematically defined tissue engineering scaffold architectures prepared by stereolithography
  publication-title: Biomaterials
  contributor:
    fullname: Grijpma
– volume: 31
  start-page: 6121
  year: 2010
  end-page: 6130
  ident: b0035
  article-title: A review on stereolithography and its applications in biomedical engineering
  publication-title: Biomaterials
  contributor:
    fullname: Grijpma
– volume: 44
  start-page: 407
  year: 1999
  end-page: 415
  ident: b0105
  article-title: Three dimensional nano-Hap–collagen matrix loading with osteogenic cells in organ culture
  publication-title: J Biomed Mater Res
  contributor:
    fullname: de Groot
– volume: 10
  start-page: 693
  year: 2006
  end-page: 712
  ident: b0155
  article-title: Schwarz meets Schwann: design and fabrication of biomorphic tissue engineering scaffolds
  publication-title: Med Image Anal
  contributor:
    fullname: Robb
– volume: 70
  start-page: 1826
  year: 2010
  end-page: 1837
  ident: b0165
  article-title: Morphology and degradation properties of PCL/HYAFF11 composite scaffolds with multi-scale degradation rate
  publication-title: Compos Sci Technol
  contributor:
    fullname: Ambrosio
– volume: 79
  start-page: 2601
  year: 1996
  end-page: 2608
  ident: b0050
  publication-title: J Am Ceram Soc
  contributor:
    fullname: Freeform fabrication of ceramics via
– volume: 16
  start-page: 523
  year: 2010
  ident: 10.1016/j.actbio.2012.12.004_b0030
  article-title: Stereolithographic bone scaffold design parameters osteogenic differentiation and signal expression
  publication-title: Tissue Eng B
  doi: 10.1089/ten.teb.2010.0171
  contributor:
    fullname: Kim
– volume: 34
  start-page: 1429
  year: 2006
  ident: 10.1016/j.actbio.2012.12.004_b0065
  article-title: Stereolithography of three-dimensional bioactive poly(ethylene glycol) constructs with encapsulated cells
  publication-title: Ann Biomed Eng
  doi: 10.1007/s10439-006-9156-y
  contributor:
    fullname: Arcaute
– volume: 18
  start-page: 2390
  issue: 16
  year: 2008
  ident: 10.1016/j.actbio.2012.12.004_b0075
  article-title: Acrylic nanocomposite resins for use in stereolithography and structural light modulation based rapid prototyping and rapid manufacturing technologies
  publication-title: Adv Funct Mater
  doi: 10.1002/adfm.200800344
  contributor:
    fullname: Gurr
– volume: 10
  start-page: 1316
  year: 2004
  ident: 10.1016/j.actbio.2012.12.004_b0055
  article-title: Rapid prototyping of tissue-engineering constructs, using photopolymerizable hydrogels and stereolithography
  publication-title: Tissue Eng
  doi: 10.1089/ten.2004.10.1316
  contributor:
    fullname: Dhariwal
– volume: 30
  start-page: 3801
  year: 2009
  ident: 10.1016/j.actbio.2012.12.004_b0060
  article-title: A poly(d,l-lactide) resin for the preparation of tissue engineering scaffolds by stereolithography
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2009.03.055
  contributor:
    fullname: Melchels
– volume: 27
  start-page: 433
  year: 1993
  ident: 10.1016/j.actbio.2012.12.004_b0135
  article-title: Hydroxylapatite/poly(l-lactide) composites: an animal study on push-out strengths and interface histology
  publication-title: J Biomed Mater Res
  doi: 10.1002/jbm.820270404
  contributor:
    fullname: Verheyen
– volume: 38
  start-page: 1257
  year: 1998
  ident: 10.1016/j.actbio.2012.12.004_b0120
  article-title: A comparison of rapid prototyping technologies
  publication-title: Int J Mach Tools Manuf
  doi: 10.1016/S0890-6955(97)00137-5
  contributor:
    fullname: Pham
– volume: 61
  start-page: 3009
  year: 2007
  ident: 10.1016/j.actbio.2012.12.004_b0140
  article-title: Effects of hydroxyapatite dosage on mechanical and biological behaviors of polylactic acid composite materials
  publication-title: Mater Lett
  doi: 10.1016/j.matlet.2006.10.064
  contributor:
    fullname: Lin
– volume: 103
  start-page: 275
  year: 2007
  ident: 10.1016/j.actbio.2012.12.004_b0090
  article-title: Nanostructured biomaterials for tissue engineering bone
  publication-title: Adv Biochem Eng Biotechnol
  contributor:
    fullname: Webster
– volume: 113
  start-page: 102
  year: 2006
  ident: 10.1016/j.actbio.2012.12.004_b0100
  article-title: Calcium phosphate cements as bone drug delivery systems: a review
  publication-title: J Control Release
  doi: 10.1016/j.jconrel.2006.04.007
  contributor:
    fullname: Ginebra
– volume: 25
  start-page: 59
  year: 2002
  ident: 10.1016/j.actbio.2012.12.004_b0045
  article-title: Complex ceramic–polymer composite microparts made by microstereolithography
  publication-title: Trans Elect Pack Man
  doi: 10.1109/TEPM.2002.1000484
  contributor:
    fullname: Provin
– volume: 16
  start-page: 113
  year: 1995
  ident: 10.1016/j.actbio.2012.12.004_b0015
  article-title: Influence of porosity on the mechanical resistance of hydroxyapatite ceramics under compressive stress
  publication-title: Biomaterials
  doi: 10.1016/0142-9612(95)98272-G
  contributor:
    fullname: Huec
– volume: 10
  start-page: 693
  year: 2006
  ident: 10.1016/j.actbio.2012.12.004_b0155
  article-title: Schwarz meets Schwann: design and fabrication of biomorphic tissue engineering scaffolds
  publication-title: Med Image Anal
  doi: 10.1016/j.media.2006.06.001
  contributor:
    fullname: Rajagopalan
– volume: 20
  start-page: 92
  year: 1998
  ident: 10.1016/j.actbio.2012.12.004_b0110
  article-title: Mechanical properties and the hierarchical structure of bone
  publication-title: Med Eng Phys
  doi: 10.1016/S1350-4533(98)00007-1
  contributor:
    fullname: Rho
– volume: 3
  start-page: 141
  year: 2009
  ident: 10.1016/j.actbio.2012.12.004_b0020
  article-title: 3D fiber deposition technique to make multifunctional and tailor-made scaffolds for tissue engineering applications
  publication-title: J Appl Biomater Bioceramics
  contributor:
    fullname: Gloria
– volume: 77A
  start-page: 396
  year: 2006
  ident: 10.1016/j.actbio.2012.12.004_b0040
  article-title: A digital micro-mirror device-based system for the microfabrication of complex, spatially patterned tissue engineering scaffolds
  publication-title: J Biomed Mater Res
  doi: 10.1002/jbm.a.30601
  contributor:
    fullname: Lu
– volume: 21
  start-page: 2529
  year: 2000
  ident: 10.1016/j.actbio.2012.12.004_b0005
  article-title: Scaffolds in tissue engineering bone and cartilage
  publication-title: Biomaterials
  doi: 10.1016/S0142-9612(00)00121-6
  contributor:
    fullname: Hutmacher
– volume: 34
  start-page: 4365
  year: 1993
  ident: 10.1016/j.actbio.2012.12.004_b0070
  article-title: Synthesis of bioabsorbable network from methacrylate-endcapped polyesters
  publication-title: Polymer
  doi: 10.1016/0032-3861(93)90203-M
  contributor:
    fullname: Storey
– volume: 414
  start-page: 773
  year: 2001
  ident: 10.1016/j.actbio.2012.12.004_b0095
  article-title: Biomaterial sacrificial bonds heal bone
  publication-title: Nature
  doi: 10.1038/414699a
  contributor:
    fullname: Currey
– volume: 4
  start-page: 107
  year: 1993
  ident: 10.1016/j.actbio.2012.12.004_b0115
  article-title: Investigation into the formation and mechanical properties of a bioactive material based on collagen and calcium phosphate
  publication-title: J Mater Sci Mater Med
  doi: 10.1007/BF00120378
  contributor:
    fullname: Clarke
– volume: 25
  start-page: 1279
  year: 2004
  ident: 10.1016/j.actbio.2012.12.004_b0080
  article-title: Hydroxyapatite/poly(epsilon caprolactone) composite coatings on hydroxyapatite porous bone scaffold for drug delivery
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2003.07.003
  contributor:
    fullname: Kim
– volume: 2
  start-page: 493
  year: 2000
  ident: 10.1016/j.actbio.2012.12.004_b0125
  article-title: Stereolithography for manufacturing ceramic parts
  publication-title: Adv Eng Mater
  doi: 10.1002/1527-2648(200008)2:8<493::AID-ADEM493>3.0.CO;2-C
  contributor:
    fullname: Doreau
– volume: 31
  start-page: 6909
  year: 2010
  ident: 10.1016/j.actbio.2012.12.004_b0150
  article-title: Mathematically defined tissue engineering scaffold architectures prepared by stereolithography
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2010.05.068
  contributor:
    fullname: Melchels
– volume: 15
  start-page: 3662
  year: 2009
  ident: 10.1016/j.actbio.2012.12.004_b0085
  article-title: Polylactic acid fibre-reinforced polycaprolactone scaffolds for bone tissue engineering
  publication-title: Tissue Eng A
  contributor:
    fullname: Guarino
– year: 2012
  ident: 10.1016/j.actbio.2012.12.004_b0160
  article-title: Finite element analysis of Schwarz P surface pore geometries for tissue-engineered scaffolds
  publication-title: Math Probl Eng
  doi: 10.1155/2012/694194
  contributor:
    fullname: Shin
– volume: 45
  start-page: 745
  issue: 5
  year: 2005
  ident: 10.1016/j.actbio.2012.12.004_b0145
  article-title: Crystallinity and mechanical properties of optically pure polylactides and their blends
  publication-title: Polym Eng Sci
  doi: 10.1002/pen.20331
  contributor:
    fullname: Sarasua
– volume: 70
  start-page: 1826
  year: 2010
  ident: 10.1016/j.actbio.2012.12.004_b0165
  article-title: Morphology and degradation properties of PCL/HYAFF11 composite scaffolds with multi-scale degradation rate
  publication-title: Compos Sci Technol
  doi: 10.1016/j.compscitech.2010.06.015
  contributor:
    fullname: Guarino
– volume: 12
  start-page: 202
  year: 1992
  ident: 10.1016/j.actbio.2012.12.004_b0010
  article-title: The critical role of geometry of porous hydroxyapatite delivery system of bone by osteogenin, a bone morphogenic protein
  publication-title: Matrix
  doi: 10.1016/S0934-8832(11)80063-6
  contributor:
    fullname: Ripamonti
– volume: 31
  start-page: 6121
  year: 2010
  ident: 10.1016/j.actbio.2012.12.004_b0035
  article-title: A review on stereolithography and its applications in biomedical engineering
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2010.04.050
  contributor:
    fullname: Melchels
– volume: 44
  start-page: 407
  year: 1999
  ident: 10.1016/j.actbio.2012.12.004_b0105
  article-title: Three dimensional nano-Hap–collagen matrix loading with osteogenic cells in organ culture
  publication-title: J Biomed Mater Res
  doi: 10.1002/(SICI)1097-4636(19990315)44:4<407::AID-JBM6>3.0.CO;2-T
  contributor:
    fullname: Du
– volume: 79
  start-page: 2601
  issue: 10
  year: 1996
  ident: 10.1016/j.actbio.2012.12.004_b0050
  publication-title: J Am Ceram Soc
  doi: 10.1111/j.1151-2916.1996.tb09022.x
  contributor:
    fullname: Griffith
– volume: 4
  start-page: 518
  year: 2005
  ident: 10.1016/j.actbio.2012.12.004_b0025
  article-title: Porous scaffold design for tissue engineering
  publication-title: Nat Mater
  doi: 10.1038/nmat1421
  contributor:
    fullname: Hollister
– volume: 23
  start-page: 1579
  year: 2002
  ident: 10.1016/j.actbio.2012.12.004_b0130
  article-title: Effect of filler content on mechanical and dynamic mechanical properties of particulate biphasic calcium phosphate–polylactide composites
  publication-title: Biomaterials
  doi: 10.1016/S0142-9612(01)00283-6
  contributor:
    fullname: Bleach
SSID ssj0038128
Score 2.4932916
Snippet The preparation of scaffolds to facilitate the replacement of damaged tissues and organs by means of tissue engineering has been much investigated. The key...
The key properties of the biomaterials used to prepare scaffolds to facilitate the replacement of damaged tissues and organs by means of tissue engineering...
SourceID proquest
crossref
pubmed
fao
elsevier
SourceType Aggregation Database
Index Database
Publisher
StartPage 5989
SubjectTerms biocompatibility
biocompatible materials
Biocompatible Materials - chemical synthesis
biodegradability
Biodegradable networks
Bone tissue engineering
CAD designed scaffold
Computer-Aided Design
Durapatite - chemistry
Equipment Design
Equipment Failure Analysis
Hydroxyapatite
Materials Testing
mixing
Nano-composites
Nanocomposites
Nanomaterials
nanoparticles
Nanostructure
Nanostructures - chemistry
Nanostructures - ultrastructure
Networks
Particle Size
Photography - methods
Polyesters - chemistry
Polymers
Resins
Resins, Synthetic - chemical synthesis
Scaffolds
Stereolithography
Surface Properties
tissue engineering
Tissue Engineering - instrumentation
Tissue Scaffolds
Title Preparation of designed poly(d,l-lactide)/nanosized hydroxyapatite composite structures by stereolithography
URI https://dx.doi.org/10.1016/j.actbio.2012.12.004
https://www.ncbi.nlm.nih.gov/pubmed/23232210
https://search.proquest.com/docview/1314709580
https://search.proquest.com/docview/1348486562
https://search.proquest.com/docview/1692373404
Volume 9
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3db9MwELfa7QUe0PhcGaAg8QCClMR2Y_dxgsJACCG6ib1FjnNmrbqkWtuH8ddzFzdpYGx8SEhVVFlJY-d-va-cf8fYk4w7tAsqCV3kRCidhtDIxIRWCZGZ3FkQtDn5YKw-HuvXIznqdOr2aJux_yppHENZ087Zv5B286M4gN9R5nhEqePxj-T-6Qw8nbd3BPOqQgO9ynlJPaU1CXQWzmg7AxHuEg1oYYpyMfmG55yc51TVYqjKeglVuTnVdBEJLbHMrjA0J3eVuBWA6uZO2nzXNZWtXZrntKnfLKvlThq9_7ksrM_i9huYnWZopSdVuvZDM_r2bDKdn_oXUf0v_XZigppEyHZiotkxsylPIgWLoXioIk_A3gc_pjGSVQPfXqfWysMW-GRLww6GvuXQ2loTu8wvLYFPSkwRlUtcM9Xw8Srv65sd_8SxPaZp0axiSrKhSuuybY6aCxXn9v670fH72rijf1O1622WUe_GrEoGL97rMm-n60x5eUxT-TaHO-zGOigJ9j2abrIOFLfY9RZV5W02a-EqKF1Q4yogXD3NXzSYevaywVPwI56CBk_BBk9Bdh5cwNMddvRmdPjqIFx36gitHOplaOPIyUTHCtDlAxtbcBI4VwBZAkkSKQeGD63NIuB5FglleCyssgPhhug6SXGXbRVlAbssADBOUbkrQCRlLjW3FLVbTbFsZnWPhfUTTeeekCWtKxWnqZdAShJI8YPX9JiqH3u6diq9s5giUn5z5S5KKTVf0dqmR2NOucEoRqscix57XIsuRXVM79hMAeVqkcYiljj9gY6uOkdqqTGQ4leck2DkpYSkadzz2GiWi0EQmuE4uv_PS9tj1zb_2AdsC4UOD1l3ka8erQH_HYlO0SU
link.rule.ids 315,782,786,27933,27934
linkProvider Elsevier
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Preparation+of+designed+poly%28d%2Cl-lactide%29%2Fnanosized+hydroxyapatite+composite+structures+by+stereolithography&rft.jtitle=Acta+biomaterialia&rft.au=Ronca%2C+A.&rft.au=Ambrosio%2C+L.&rft.au=Grijpma%2C+D.W.&rft.date=2013-04-01&rft.pub=Elsevier+Ltd&rft.issn=1742-7061&rft.eissn=1878-7568&rft.volume=9&rft.issue=4&rft.spage=5989&rft.epage=5996&rft_id=info:doi/10.1016%2Fj.actbio.2012.12.004&rft.externalDocID=S1742706112005880
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1742-7061&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1742-7061&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1742-7061&client=summon