Expression of adhesion proteins (E-cadherin and β-catenin) and cell proliferation (Ki-67) at the invasive tumor front in conventional oral squamous cell and basaloid squamous cell carcinomas

• Published in: Archives of oral biology Vol. 61; pp. 8 - 15
• Main Authors: Pereira, Carlos Henrique, Morais, Marília Oliveira, Martins, Allisson Filipe Lopes, Soares, Mariana Quirino Silveira, Alencar, Rita de Cássia Gonçalves, Batista, Aline Carvalho, Leles, Cláudio Rodrigues, Mendonça, Elismauro Francisco
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01-01-2016
• Subjects: Advanced Basic Science; Basaloid squamous cell carcinoma; beta Catenin - metabolism; Cadherins - metabolism; Carcinoma, Squamous Cell - metabolism; Carcinoma, Squamous Cell - pathology; Cell Proliferation; Dentistry; E-cadherin; Female; Front invasion tumoral; Humans; Immunohistochemistry; Ki-67 Antigen - metabolism; Ki-67 protein; Male; Middle Aged; Mouth Neoplasms - metabolism; Mouth Neoplasms - pathology; Risk Factors; Squamous cell carcinoma; Survival Analysis; β-catenin; hematoxylin and eosin; PBS; World Health Organization; CI; Front invasion tumoral; invasive tumor front; Ki-67 protein; E-cadherin; EMT; BSCC; HPV; β-catenin; SCC; epithelial mesenchymal transition; β-cat; basaloid squamous cell carcinoma; human papillomavirus; phosphate buffer solution; ITF; confidence interval; E-cad; HE; squamous cell carcinoma; WHO; Squamous cell carcinoma; Basaloid squamous cell carcinoma
• ISSN: 0003-9969; 1879-1506
• DOI: 10.1016/j.archoralbio.2015.10.003

Highlights • E-cad, B-Cat and Ki-67 were investigated in oral SCC and BSCC. • There is no difference of expression of B-cat and E-cad in oral SCC and BSCC. • Lower expression of E-Cad and B-cat in cytoplasmic membrane and high in cytoplasm. • Ki-67 expression has no significance in the ITF of SCC and BSCC in oral cavity. • There is no significant difference between these lesions in oral cavity.