Mutations in the rpoB Gene of Multidrug-Resistant Mycobacterium tuberculosis Isolates from Brazil
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| Published in: | Journal of Clinical Microbiology Vol. 38; no. 8; pp. 3119 - 3122 |
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| AbstractList | Mutations in a 69-bp region of the
rpoB
gene associated with rifampin resistance (Rif
r
) in 100 isolates (82 Rif
r
) from three states of Brazil were studied. Twenty-one different kinds of mutations were identified in the Rif
r
isolates, and six new alleles are described. Mutations in a 69-bp region of the rpoB gene associated with rifampin resistance (Rif super(r)) in 100 isolates (82 Rif super(r)) from three states of Brazil were studied. Twenty-one different kinds of mutations were identified in the Rif super(r) isolates, and six new alleles are described. Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue JCM About JCM Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy JCM RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0095-1137 Online ISSN: 1098-660X Copyright © 2014 by the American Society for Microbiology. For an alternate route to JCM .asm.org, visit: JCM Mutations in a 69-bp region of the rpoB gene associated with rifampin resistance (Rif(r)) in 100 isolates (82 Rif(r)) from three states of Brazil were studied. Twenty-one different kinds of mutations were identified in the Rif(r) isolates, and six new alleles are described. |
| Author | Arnaldo Zaha Andréia Rosane M. Valim Maria Lucia R. Rossetti Marta O. Ribeiro |
| AuthorAffiliation | Laboratório Central do Rio Grande do Sul, Fundação Estadual de Produção e Pesquisa em Saúde, Porto Alegre—Rio Grande do Sul CEP 90130-001, 1 and Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Porto Alegre—Rio Grande do Sul CEP 91501-970, 2 Brazil |
| AuthorAffiliation_xml | – name: Laboratório Central do Rio Grande do Sul, Fundação Estadual de Produção e Pesquisa em Saúde, Porto Alegre—Rio Grande do Sul CEP 90130-001, 1 and Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Porto Alegre—Rio Grande do Sul CEP 91501-970, 2 Brazil |
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| Keywords | Typing Genotype Allele Antibiotic Mycobacterium tuberculosis Mycobacteriales Multiple resistance Mycobacteriaceae Molecular epidemiology Bacteria Actinomycetes Antituberculous agent Mutation |
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Mendeley... Mutations in a 69-bp region of the rpoB gene associated with rifampin resistance (Rif(r)) in 100 isolates (82 Rif(r)) from three states of Brazil were studied.... Mutations in a 69-bp region of the rpoB gene associated with rifampin resistance (Rif r ) in 100 isolates (82 Rif r ) from three states of Brazil were studied.... Mutations in a 69-bp region of the rpoB gene associated with rifampin resistance (Rif super(r)) in 100 isolates (82 Rif super(r)) from three states of Brazil... |
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| StartPage | 3119 |
| SubjectTerms | Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Antitubercular Agents - pharmacology Bacteriology Biological and medical sciences Brazil Brazil - epidemiology DNA-Directed RNA Polymerases - genetics Drug Resistance, Microbial - genetics Drug Resistance, Multiple - genetics Epidemiology Fundamental and applied biological sciences. Psychology Genes, Bacterial Humans Medical sciences Microbial Sensitivity Tests Microbiology Molecular Sequence Data Mutation Mycobacteriology and Aerobic Actinomycetes Mycobacterium tuberculosis Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - enzymology Mycobacterium tuberculosis - genetics Pharmacology. Drug treatments rpoB gene Sequence Analysis, DNA Tuberculosis, Pulmonary - epidemiology Tuberculosis, Pulmonary - microbiology |
| Title | Mutations in the rpoB Gene of Multidrug-Resistant Mycobacterium tuberculosis Isolates from Brazil |
| URI | http://jcm.asm.org/content/38/8/3119.abstract https://www.ncbi.nlm.nih.gov/pubmed/10921994 https://search.proquest.com/docview/17627654 https://search.proquest.com/docview/71255650 https://pubmed.ncbi.nlm.nih.gov/PMC87207 |
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