Symptom remission and functional outcome in an Egyptian sample of patients with schizophrenia

Background The ultimate treatment goal of schizophrenia is regaining patients’ pre-morbid function. Results Ninety-three outpatients with schizophrenia, diagnosed according to the criteria of Diagnostic and Statistical Manual of Mental Disorders—fourth edition (DSM-IV), were recruited, of whom 35 pa...

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Bibliographic Details
Published in:Middle East current psychiatry (Cairo) Vol. 28; no. 1; pp. 1 - 9
Main Authors: El Ghamry, Reem, Saad, Ahmed, Elbatrawy, Amira Nassieb, Hassan, Ghada A. M., Rabie, Eman S., Mohamed, Mohamed Youssef
Format: Journal Article
Language:English
Published: Berlin/Heidelberg Springer Berlin Heidelberg 20-12-2021
Springer Nature B.V
SpringerOpen
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Summary:Background The ultimate treatment goal of schizophrenia is regaining patients’ pre-morbid function. Results Ninety-three outpatients with schizophrenia, diagnosed according to the criteria of Diagnostic and Statistical Manual of Mental Disorders—fourth edition (DSM-IV), were recruited, of whom 35 patients (37.6%) had achieved the remission severity criteria, whereas 58 patients (62.4%) failed to fulfill the criteria for remission. The functional aspects were examined by the Global Assessment of Functioning scale (GAF) and the Social Functioning Questionnaire (SFQ). Predictors of outcome were examined by applying binary logistic regression analysis. Patients who fulfilled those specific criteria for remission showed a favorable outcome in the assessed areas, regarding GAF and social functioning in society. Lack of judgment or insight item of PANSS showed significantly good functional outcomes. Conclusion The results suggest that the remission concept has important implications for the treatment of schizophrenia. Remission seems to be associated with better functional capabilities. However, this does not necessarily mean that remitted patients have “adequate” functioning, especially regarding the social skills domain.
ISSN:2090-5416
2090-5408
2090-5416
DOI:10.1186/s43045-021-00156-y