Acceptability of Community-Based Tuberculosis Preventive Treatment for People Living with HIV in Zimbabwe

• Published in: Healthcare (Basel) Vol. 10; no. 1; p. 116
• Main Authors: Msukwa, Martin K, Mapingure, Munyaradzi P, Zech, Jennifer M, Masvawure, Tsitsi B, Mantell, Joanne E, Musuka, Godfrey, Apollo, Tsitsi, Boccanera, Rodrigo, Chingombe, Innocent, Gwanzura, Clorata, Howard, Andrea A, Rabkin, Miriam
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 07-01-2022; MDPI
• Subjects: Adults; Bilingualism; Data collection; differentiated service delivery; Focus groups; Health facilities; HIV; Human immunodeficiency virus; integration; TB prevention; TPT; Tuberculosis; Zimbabwe; United States > US; Zimbabwe; integration; TPT; Zimbabwe; HIV; TB prevention; differentiated service delivery
• ISSN: 2227-9032; 2227-9032
• DOI: 10.3390/healthcare10010116

As Zimbabwe expands tuberculosis preventive treatment (TPT) for people living with HIV (PLHIV), the Ministry of Health and Child Care is considering making TPT more accessible to PLHIV via less-intensive differentiated service delivery models such as Community ART Refill Groups (CARGs). We designed a study to assess the feasibility and acceptability of integrating TPT into CARGs among key stakeholders, including CARG members, in Zimbabwe. We conducted 45 key informant interviews (KII) with policy makers, implementers, and CARG leaders; 16 focus group discussions (FGD) with 136 PLHIV in CARGs; and structured observations of 8 CARG meetings. KII and FGD were conducted in English and Shona. CARG observations were conducted using a structured checklist and time-motion data capture. Ninety six percent of participants supported TPT integration into CARGs and preferred multi-month TPT dispensing aligned with ART dispensing schedules. Participants noted that the existing CARG support systems could be used for TB symptom screening and TPT adherence monitoring/support. Other perceived advantages included convenience for PLHIV and decreased health facility provider workloads. Participants expressed concerns about possible medication stockouts and limited knowledge about TPT among CARG leaders but were confident that CARGs could effectively provide community-based TPT education, adherence monitoring/support, and TB symptom screening provided that CARG leaders received appropriate training and supervision. These results are consistent with findings from pilot projects in other African countries that are scaling up both differentiated service delivery for HIV and TPT and suggest that designing contextually appropriate approaches to integrating TPT into less-intensive HIV treatment models is an effective way to reach people who are established on ART but who may have missed out on access to TPT.