IncI1 plasmids associated with the spread of CMY-2, CTX-M-1 and SHV-12 in Escherichia coli of animal and human origin

• Published in: Clinical microbiology and infection Vol. 19; no. 5; pp. E238 - E240
• Main Authors: Accogli, M., Fortini, D., Giufrè, M., Graziani, C., Dolejska, M., Carattoli, A., Cerquetti, M.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01-05-2013; Elsevier Limited
• Subjects: Animals; beta-Lactamases - genetics; Birds; ESBL; Escherichia coli; Escherichia coli - classification; Escherichia coli - enzymology; Escherichia coli - genetics; Escherichia coli - isolation & purification; Escherichia coli Infections - microbiology; Escherichia coli Infections - veterinary; Humans; Multilocus Sequence Typing; PBRT; Plasmids - classification; Plasmids - isolation & purification; pMLST; Restriction Mapping; Salmonella; Zoonosis; ESBL; PBRT; Zoonosis; Escherichia coli; pMLST
• ISSN: 1198-743X; 1469-0691
• DOI: 10.1111/1469-0691.12128

Fourteen plasmids carrying blaCTC-M-1, blaSHV-12 or blaCMY-2 genes from Escherichia coli of both avian and human origin were analysed. IncI1 plasmids were largely predominant. Plasmid mutilocus sequence typing and comparative analysis revealed that the blaCMY-2-ST12-IncI1 plasmids from avian E. coli were identical to those previously found in Salmonella from humans, but different to those associated with human E. coli. The IncI1-ST3 plasmids carrying blaCTX-M-1 or blaSHV-12 were related to those previously identified in avian E. coli, but different to those identified in human E. coli. Overall, no plasmids shared by E. coli of both origin (human/avian) were identified; however, further investigations are needed.