Multiple COVID-19 vaccine doses in CLL and MBL improve immune responses with progressive and high seroconversion

•Multiple doses result in high rates of seroconversion in CLL (94.2%) and MBL (100%), with progressively higher antispike antibody levels.•Neutralization against COVID-19 variants requires strong specific T-cell responses and higher antispike levels. [Display omitted] Patients with chronic lymphocyt...

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Bibliographic Details

Published in:	Blood Vol. 140; no. 25; pp. 2709 - 2721
Main Authors:	Shen, Yandong, Freeman, Jane A., Holland, Juliette, Naidu, Kartik, Solterbeck, Ann, Van Bilsen, Nenna, Downe, Paul, Kerridge, Ian, Wallman, Lucinda, Akerman, Anouschka, Aggarwal, Anupriya, Milogiannakis, Vanessa, Martins Costa Gomes, Gabriela, Doyle, Chloe M., Sandgren, Kerrie J., Turville, Stuart, Cunningham, Anthony L., Mulligan, Stephen P.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 22-12-2022 by The American Society of Hematology
Subjects:	Antibodies, Viral COVID-19 - prevention & control COVID-19 Vaccines Humans Immunity Immunoglobulin G Immunoglobulin M Leukemia, Lymphocytic, Chronic, B-Cell - therapy Lymphocytosis Regular SARS-CoV-2 Seroconversion
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