Minicircle kDNA microheterogeneity in Endotrypanum indicate diversity within this genus

A comparison of kDNA restriction-endonuclease fragment patterns from strains representing selected Endotrypanum zymodemes was done by schizodeme analysis. As the degree of heterogeneity within mini-circles varied among species or strains of Endotrypanum, the fingerprint obtained with each of the res...

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Bibliographic Details
Published in:	Memórias do Instituto Oswaldo Cruz Vol. 95; no. 2; pp. 189 - 191
Main Authors:	Franco, A M, Machado, G M, Moreira, C F, Grimaldi, Jr, G
Format:	Journal Article
Language:	English
Published:	Brazil Instituto Oswaldo Cruz, Ministério da Saúde 01-04-2000 Fundação Oswaldo Cruz (FIOCRUZ)
Subjects:	Animals DNA, Kinetoplast - analysis Endotrypanum Genetic Heterogeneity Genetic Variation - genetics Isoenzymes - genetics Leishmania - classification Leishmania - enzymology Leishmania - genetics minicircle kDNA analysis PARASITOLOGY Polymorphism, Genetic - genetics TROPICAL MEDICINE Trypanosomatidae Trypanosomatina - classification Trypanosomatina - enzymology Trypanosomatina - genetics zymodemes Trypanosomatidae Endotrypanum minicircle kDNA analysis
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Summary:	A comparison of kDNA restriction-endonuclease fragment patterns from strains representing selected Endotrypanum zymodemes was done by schizodeme analysis. As the degree of heterogeneity within mini-circles varied among species or strains of Endotrypanum, the fingerprint obtained with each of the restriction enzymes was unique for each of these parasites. The data have revealed that this trypanosomatid genus is much more complex than it was originally thought to be.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2
ISSN:	0074-0276 1678-8060 0074-0276 1678-8060
DOI:	10.1590/S0074-02762000000200009