DNA methylation profiling in cell models of diabetic nephropathy

We have previously identified differentially expressed genes in cell models of diabetic nephropathy and renal biopsies. Here we have performed quantitative DNA methylation profiling in cell models of diabetic nephropathy. Over 3,000 CpG units in the promoter regions of 192 candidate genes were asses...

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Bibliographic Details
Published in:	Epigenetics Vol. 5; no. 5; pp. 396 - 401
Main Authors:	Brennan, Eoin P, Ehrich, Mathias, O'Donovan, Helen, Brazil, Derek P, Crean, John K, Murphy, Madeline, Sadlier, Denise M, Martin, Finian, Godson, Catherine, van den Boom, Dirk, Maxwell, Alexander P, Savage, David A
Format:	Journal Article
Language:	English
Published:	United States 01-07-2010
Subjects:	Binding Biology Bioscience Calcium Cancer Cell CpG Islands - genetics Cycle Diabetic Nephropathies - genetics DNA Methylation Epigenesis, Genetic Epithelial Cells - metabolism Gene Expression Profiling - methods Genome, Human - genetics Humans Landes Mesangial Cells - metabolism Oligonucleotide Array Sequence Analysis Organogenesis Promoter Regions, Genetic Proteins
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