The Brain Observatory Storage Service and Database (BossDB): A Cloud-Native Approach for Petascale Neuroscience Discovery

• Published in: Frontiers in neuroinformatics Vol. 16; p. 828787
• Main Authors: Hider, Jr, Robert, Kleissas, Dean, Gion, Timothy, Xenes, Daniel, Matelsky, Jordan, Pryor, Derek, Rodriguez, Luis, Johnson, Erik C, Gray-Roncal, William, Wester, Brock
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 15-02-2022; Frontiers Media S.A
• Subjects: Annotations; Archives & records; Automation; Brain research; cloud; connectome; data; Data acquisition; Datasets; imaging; Laboratories; Medical imaging; Nervous system; Neuroimaging; Neuroscience; Observatories; Open source software; software; storage; Visualization; cloud; data; software; connectome; electron microscopy; X-ray; storage; imaging
• ISSN: 1662-5196; 1662-5196
• DOI: 10.3389/fninf.2022.828787

Technological advances in imaging and data acquisition are leading to the development of petabyte-scale neuroscience image datasets. These large-scale volumetric datasets pose unique challenges since analyses often span the entire volume, requiring a unified platform to access it. In this paper, we describe the Brain Observatory Storage Service and Database (BossDB), a cloud-based solution for storing and accessing petascale image datasets. BossDB provides support for data ingest, storage, visualization, and sharing through a RESTful Application Programming Interface (API). A key feature is the scalable indexing of spatial data and automatic and manual annotations to facilitate data discovery. Our project is open source and can be easily and cost effectively used for a variety of modalities and applications, and has effectively worked with datasets over a petabyte in size.