A new animal diet based on human Western diet is a robust diet-induced obesity model: comparison to high-fat and cafeteria diets in term of metabolic and gut microbiota disruption
Background/Objectives: Obesity is a metabolic disorder that predisposes patients to numerous diseases and has become a major global public-health concern. Animal models of diet-induced obesity (DIO) are frequently used to study obesity, but which DIO model most accurately reflects the pathology of h...
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| Published in: | International Journal of Obesity Vol. 42; no. 3; pp. 525 - 534 |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
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London
Nature Publishing Group UK
01-03-2018
Nature Publishing Group |
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| Abstract | Background/Objectives:
Obesity is a metabolic disorder that predisposes patients to numerous diseases and has become a major global public-health concern. Animal models of diet-induced obesity (DIO) are frequently used to study obesity, but which DIO model most accurately reflects the pathology of human obesity remains unclear. In this study, we designed a diet based on the human Western diet (WD) and compared it with the cafeteria diet (CAF) and high-fat diet (HFD) in order to evaluate which diet most closely mirrors human obesity.
Methods:
Wistar rats were fed four different diets (WD, CAF, HFD and a low-fat diet) for 18 weeks. Metabolic parameters and gut microbiota changes were then characterized.
Results:
Rats fed the four different diets exhibited completely different phenotypes, highlighting the importance of diet selection. This study also revealed that WD most effectively induced obesity and obesity-related disorders, and thus proved to be a robust model of human obesity. Moreover, WD-fed rats developed obesity and obesity-related comorbidities independent of major alterations in gut microbiota composition (dysbiosis), whereas CAF-fed rats developed the greatest dysbiosis independent of obesity. We also characterized gut microbiota after feeding on these four different diets and identified five genera that might be involved in the pathogenesis of obesity.
Conclusions:
These data suggest that diet, and not the obese state, was the major driving force behind gut microbiota changes. Moreover, the marked dysbiosis observed in CAF-fed rats might have resulted from the presence of several additives present in the CAF diet, or even a lack of essential vitamins and minerals. Based on our findings, we recommend the use of the prototypic WD (designed here) in DIO models. Conversely, CAF could be used to investigate the effects of excessive consumption of industrially produced and highly processed foods, which are characteristic of Western society. |
|---|---|
| AbstractList | Background/Objectives:
Obesity is a metabolic disorder that predisposes patients to numerous diseases and has become a major global public-health concern. Animal models of diet-induced obesity (DIO) are frequently used to study obesity, but which DIO model most accurately reflects the pathology of human obesity remains unclear. In this study, we designed a diet based on the human Western diet (WD) and compared it with the cafeteria diet (CAF) and high-fat diet (HFD) in order to evaluate which diet most closely mirrors human obesity.
Methods:
Wistar rats were fed four different diets (WD, CAF, HFD and a low-fat diet) for 18 weeks. Metabolic parameters and gut microbiota changes were then characterized.
Results:
Rats fed the four different diets exhibited completely different phenotypes, highlighting the importance of diet selection. This study also revealed that WD most effectively induced obesity and obesity-related disorders, and thus proved to be a robust model of human obesity. Moreover, WD-fed rats developed obesity and obesity-related comorbidities independent of major alterations in gut microbiota composition (dysbiosis), whereas CAF-fed rats developed the greatest dysbiosis independent of obesity. We also characterized gut microbiota after feeding on these four different diets and identified five genera that might be involved in the pathogenesis of obesity.
Conclusions:
These data suggest that diet, and not the obese state, was the major driving force behind gut microbiota changes. Moreover, the marked dysbiosis observed in CAF-fed rats might have resulted from the presence of several additives present in the CAF diet, or even a lack of essential vitamins and minerals. Based on our findings, we recommend the use of the prototypic WD (designed here) in DIO models. Conversely, CAF could be used to investigate the effects of excessive consumption of industrially produced and highly processed foods, which are characteristic of Western society. Background/Objectives:Obesity is a metabolic disorder that predisposes patients to numerous diseases and has become a major global public-health concern. Animal models of diet-induced obesity (DIO) are frequently used to study obesity, but which DIO model most accurately reflects the pathology of human obesity remains unclear. In this study, we designed a diet based on the human Western diet (WD) and compared it with the cafeteria diet (CAF) and high-fat diet (HFD) in order to evaluate which diet most closely mirrors human obesity.Methods:Wistar rats were fed four different diets (WD, CAF, HFD and a low-fat diet) for 18 weeks. Metabolic parameters and gut microbiota changes were then characterized.Results:Rats fed the four different diets exhibited completely different phenotypes, highlighting the importance of diet selection. This study also revealed that WD most effectively induced obesity and obesity-related disorders, and thus proved to be a robust model of human obesity. Moreover, WD-fed rats developed obesity and obesity-related comorbidities independent of major alterations in gut microbiota composition (dysbiosis), whereas CAF-fed rats developed the greatest dysbiosis independent of obesity. We also characterized gut microbiota after feeding on these four different diets and identified five genera that might be involved in the pathogenesis of obesity.Conclusions:These data suggest that diet, and not the obese state, was the major driving force behind gut microbiota changes. Moreover, the marked dysbiosis observed in CAF-fed rats might have resulted from the presence of several additives present in the CAF diet, or even a lack of essential vitamins and minerals. Based on our findings, we recommend the use of the prototypic WD (designed here) in DIO models. Conversely, CAF could be used to investigate the effects of excessive consumption of industrially produced and highly processed foods, which are characteristic of Western society. Background/Objectives: Obesity is a metabolic disorder that predisposes patients to numerous diseases and has become a major global public-health concern. Animal models of diet-induced obesity (DIO) are frequently used to study obesity, but which DIO model most accurately reflects the pathology of human obesity remains unclear. In this study, we designed a diet based on the human Western diet (WD) and compared it with the cafeteria diet (CAF) and high-fat diet (HFD) in order to evaluate which diet most closely mirrors human obesity. Methods: Wistar rats were fed four different diets (WD, CAF, HFD and a low-fat diet) for 18 weeks. Metabolic parameters and gut microbiota changes were then characterized. Results: Rats fed the four different diets exhibited completely different phenotypes, highlighting the importance of diet selection. This study also revealed that WD most effectively induced obesity and obesity-related disorders, and thus proved to be a robust model of human obesity. Moreover, WD-fed rats developed obesity and obesity-related comorbidities independent of major alterations in gut microbiota composition (dysbiosis), whereas CAF-fed rats developed the greatest dysbiosis independent of obesity. We also characterized gut microbiota after feeding on these four different diets and identified five genera that might be involved in the pathogenesis of obesity. Conclusions: These data suggest that diet, and not the obese state, was the major driving force behind gut microbiota changes. Moreover, the marked dysbiosis observed in CAF-fed rats might have resulted from the presence of several additives present in the CAF diet, or even a lack of essential vitamins and minerals. Based on our findings, we recommend the use of the prototypic WD (designed here) in DIO models. Conversely, CAF could be used to investigate the effects of excessive consumption of industrially produced and highly processed foods, which are characteristic of Western society. International Journal of Obesity (2018) 42, 525-534; doi: 10.1038/ijo.2017.225; published online 3 October 2017 Obesity is a metabolic disorder that predisposes patients to numerous diseases and has become a major global public-health concern. Animal models of diet-induced obesity (DIO) are frequently used to study obesity, but which DIO model most accurately reflects the pathology of human obesity remains unclear. In this study, we designed a diet based on the human Western diet (WD) and compared it with the cafeteria diet (CAF) and high-fat diet (HFD) in order to evaluate which diet most closely mirrors human obesity. Wistar rats were fed four different diets (WD, CAF, HFD and a low-fat diet) for 18 weeks. Metabolic parameters and gut microbiota changes were then characterized. Rats fed the four different diets exhibited completely different phenotypes, highlighting the importance of diet selection. This study also revealed that WD most effectively induced obesity and obesity-related disorders, and thus proved to be a robust model of human obesity. Moreover, WD-fed rats developed obesity and obesity-related comorbidities independent of major alterations in gut microbiota composition (dysbiosis), whereas CAF-fed rats developed the greatest dysbiosis independent of obesity. We also characterized gut microbiota after feeding on these four different diets and identified five genera that might be involved in the pathogenesis of obesity. These data suggest that diet, and not the obese state, was the major driving force behind gut microbiota changes. Moreover, the marked dysbiosis observed in CAF-fed rats might have resulted from the presence of several additives present in the CAF diet, or even a lack of essential vitamins and minerals. Based on our findings, we recommend the use of the prototypic WD (designed here) in DIO models. Conversely, CAF could be used to investigate the effects of excessive consumption of industrially produced and highly processed foods, which are characteristic of Western society. BACKGROUND/OBJECTIVESObesity is a metabolic disorder that predisposes patients to numerous diseases and has become a major global public-health concern. Animal models of diet-induced obesity (DIO) are frequently used to study obesity, but which DIO model most accurately reflects the pathology of human obesity remains unclear. In this study, we designed a diet based on the human Western diet (WD) and compared it with the cafeteria diet (CAF) and high-fat diet (HFD) in order to evaluate which diet most closely mirrors human obesity. METHODSWistar rats were fed four different diets (WD, CAF, HFD and a low-fat diet) for 18 weeks. Metabolic parameters and gut microbiota changes were then characterized. RESULTSRats fed the four different diets exhibited completely different phenotypes, highlighting the importance of diet selection. This study also revealed that WD most effectively induced obesity and obesity-related disorders, and thus proved to be a robust model of human obesity. Moreover, WD-fed rats developed obesity and obesity-related comorbidities independent of major alterations in gut microbiota composition (dysbiosis), whereas CAF-fed rats developed the greatest dysbiosis independent of obesity. We also characterized gut microbiota after feeding on these four different diets and identified five genera that might be involved in the pathogenesis of obesity. CONCLUSIONSThese data suggest that diet, and not the obese state, was the major driving force behind gut microbiota changes. Moreover, the marked dysbiosis observed in CAF-fed rats might have resulted from the presence of several additives present in the CAF diet, or even a lack of essential vitamins and minerals. Based on our findings, we recommend the use of the prototypic WD (designed here) in DIO models. Conversely, CAF could be used to investigate the effects of excessive consumption of industrially produced and highly processed foods, which are characteristic of Western society. Obesity is a metabolic disorder that predisposes patients to numerous diseases and has become a major global public-health concern. Animal models of diet-induced obesity (DIO) are frequently used to study obesity, but which DIO model most accurately reflects the pathology of human obesity remains unclear. In this study, we designed a diet based on the human Western diet (WD) and compared it with the cafeteria diet (CAF) and high-fat diet (HFD) in order to evaluate which diet most closely mirrors human obesity. Wistar rats were fed four different diets (WD, CAF, HFD and a low-fat diet) for 18 weeks. Metabolic parameters and gut microbiota changes were then characterized. Rats fed the four different diets exhibited completely different phenotypes, highlighting the importance of diet selection. This study also revealed that WD most effectively induced obesity and obesity-related disorders, and thus proved to be a robust model of human obesity. Moreover, WD-fed rats developed obesity and obesity-related comorbidities independent of major alterations in gut microbiota composition (dysbiosis), whereas CAF-fed rats developed the greatest dysbiosis independent of obesity. We also characterized gut microbiota after feeding on these four different diets and identified five genera that might be involved in the pathogenesis of obesity. These data suggest that diet, and not the obese state, was the major driving force behind gut microbiota changes. Moreover, the marked dysbiosis observed in CAF-fed rats might have resulted from the presence of several additives present in the CAF diet, or even a lack of essential vitamins and minerals. Based on our findings, we recommend the use of the prototypic WD (designed here) in DIO models. Conversely, CAF could be used to investigate the effects of excessive consumption of industrially produced and highly processed foods, which are characteristic of Western society. |
| Audience | Academic |
| Author | Chaves, P R Vargas, A R Rabelo, T K Silveira, A K Bortolin, R C Martinello, Kd B Moreira, J C F Gasparotto, J Schnorr, C E Gelain, D P |
| Author_xml | – sequence: 1 givenname: R C surname: Bortolin fullname: Bortolin, R C email: rafaelbortolin@hotmail.com organization: Centro de Estudos em Estresse Oxidativo—Departamento de Bioquímica – Instituto de Ciências Básicas da Saúde—Universidade Federal do Rio Grande do Sul (UFRGS) – sequence: 2 givenname: A R surname: Vargas fullname: Vargas, A R organization: Centro de Estudos em Estresse Oxidativo—Departamento de Bioquímica – Instituto de Ciências Básicas da Saúde—Universidade Federal do Rio Grande do Sul (UFRGS) – sequence: 3 givenname: J orcidid: 0000-0003-2545-7288 surname: Gasparotto fullname: Gasparotto, J organization: Centro de Estudos em Estresse Oxidativo—Departamento de Bioquímica – Instituto de Ciências Básicas da Saúde—Universidade Federal do Rio Grande do Sul (UFRGS) – sequence: 4 givenname: P R surname: Chaves fullname: Chaves, P R organization: Centro de Estudos em Estresse Oxidativo—Departamento de Bioquímica – Instituto de Ciências Básicas da Saúde—Universidade Federal do Rio Grande do Sul (UFRGS) – sequence: 5 givenname: C E surname: Schnorr fullname: Schnorr, C E organization: Centro de Estudos em Estresse Oxidativo—Departamento de Bioquímica – Instituto de Ciências Básicas da Saúde—Universidade Federal do Rio Grande do Sul (UFRGS) – sequence: 6 givenname: Kd B surname: Martinello fullname: Martinello, Kd B organization: Departamento de Ingeniería Civil y Ambiental—Universidad de la Costa – sequence: 7 givenname: A K surname: Silveira fullname: Silveira, A K organization: Centro de Estudos em Estresse Oxidativo—Departamento de Bioquímica – Instituto de Ciências Básicas da Saúde—Universidade Federal do Rio Grande do Sul (UFRGS) – sequence: 8 givenname: T K surname: Rabelo fullname: Rabelo, T K organization: Departamento de Educação em Saúde—Campus Universitário Professor Antônio Garcia Filho—Universidade Federal de Sergipe (UFS) – sequence: 9 givenname: D P surname: Gelain fullname: Gelain, D P organization: Centro de Estudos em Estresse Oxidativo—Departamento de Bioquímica – Instituto de Ciências Básicas da Saúde—Universidade Federal do Rio Grande do Sul (UFRGS) – sequence: 10 givenname: J C F surname: Moreira fullname: Moreira, J C F organization: Centro de Estudos em Estresse Oxidativo—Departamento de Bioquímica – Instituto de Ciências Básicas da Saúde—Universidade Federal do Rio Grande do Sul (UFRGS) |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28895587$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1038/nm0106-75 10.1159/000282080 10.1093/glycob/cwu057 10.1038/nature12506 10.1038/505612a 10.1128/IAI.00908-10 10.1371/journal.pone.0126931 10.1093/jn/117.2.227 10.1111/j.1440-1746.2006.04701.x 10.1093/ajcn.81.2.341 10.5402/2012/103472 10.1016/S0140-6736(05)67483-1 10.1186/1475-2891-11-34 10.3390/nu4081095 10.1016/j.mam.2012.11.001 10.1016/j.immuni.2014.05.014 10.1038/nature18846 10.1038/aps.2011.203 10.3748/wjg.v20.i26.8364 10.1038/oby.2011.18 10.1155/2016/7238679 10.1097/MIB.0000000000000750 10.1007/s12263-014-0406-6 10.1038/nature11552 10.1111/j.1464-5491.2005.01748.x 10.1126/science.1208344 10.1016/j.physbeh.2012.04.004 10.1038/nature.2016.19335 10.1093/jn/123.11.1939 10.1016/j.pcad.2013.10.003 10.1016/j.chom.2008.02.015 10.1038/oby.2007.608 10.1177/0884533610386234 10.1038/nri2921 10.1210/jc.2003-030214 10.1186/s13073-016-0303-2 10.1017/S0954422410000168 10.1038/srep32484 10.1111/j.1753-4887.2009.00246.x 10.1126/science.aah7199 |
| ContentType | Journal Article |
| Copyright | Macmillan Publishers Limited, part of Springer Nature. 2018 COPYRIGHT 2018 Nature Publishing Group Copyright Nature Publishing Group Mar 2018 |
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| DOI | 10.1038/ijo.2017.225 |
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| References | Nilsson, Raun, Yan, Larsen, Tang-Christensen (CR6) 2012; 33 Moore (CR9) 1987; 117 Rosini, Ramos da Silva, de Moraes (CR34) 2012; 58 Shen, Obin, Zhao (CR10) 2013; 34 Sonnenburg, Bäckhed (CR11) 2016; 535 Collins, Tabak (CR42) 2014; 505 Cordain, Eaton, Sebastian, Mann, Lindeberg, Watkins (CR3) 2005; 81 Reardon (CR41) 2016; 530 Zeisel, da Costa (CR29) 2009; 67 Tremaroli, Bäckhed (CR37) 2012; 489 CR17 Adams, Angulo (CR23) 2005; 22 CR14 Veteläinen, van Vliet, van Gulik (CR28) 2007; 22 Le Chatelier, Nielsen, Qin, Prifti, Hildebrand, Falony (CR32) 2013; 500 Lecomte, Kaakoush, Maloney, Raipuria, Huinao, Mitchell (CR12) 2015; 10 Ahmad, Khan, Akhter, Khan, Khan, Ashraf (CR26) 2014; 24 Brown, DeCoffe, Molcan, Gibson (CR39) 2012; 4 Buettner, Schölmerich, Bollheimer (CR5) 2007; 15 Via (CR36) 2012; 2012 Oliveros, Somers, Sochor, Goel, Lopez-Jimenez (CR19) 2014; 56 de Macedo, de Freitas, da Silva Torres (CR21) 2016; 2016 Berthoud, Zheng (CR18) 2012; 107 Turnbaugh, Bäckhed, Fulton, Gordon (CR31) 2008; 3 Higa, Spinola, Fonseca-Alaniz (CR8) 2014; 6 Casadevall, Fang (CR43) 2010; 78 Teodoro, Varela, Rolo, Palmeira (CR27) 2014; 9 Thorburn, Macia, Mackay (CR20) 2014; 40 CR4 DeGruttola, Low, Mizoguchi, Mizoguchi (CR33) 2016; 22 Smyth, Heron (CR2) 2006; 12 Haslam, James (CR1) 2005; 366 Damms-Machado, Weser, Bischoff (CR35) 2012; 11 Grotto, Zied (CR16) 2010; 25 Sampey, Vanhoose, Winfield, Freemerman, Muehlbauer, Fueger (CR7) 2011; 19 Reeves, Nielsen, Fahey (CR15) 1993; 123 Hariri, Thibault (CR45) 2010; 23 CR44 Rabot, Membrez, Blancher, Berger, Moine, Krause (CR40) 2016; 6 Boulangé, Neves, Chilloux, Nicholson, Dumas (CR13) 2016; 8 Kucera (CR30) 2014; 20 Wu, Chen, Hoffmann, Bittinger, Chen, Keilbaugh (CR38) 2011; 334 Bellentani, Scaglioni, Marino, Bedogni (CR22) 2010; 28 Gavrila, Chan, Yiannakouris, Kontogianni, Miller, Orlova (CR25) 2003; 88 Ouchi, Parker, Lugus, Walsh (CR24) 2011; 11 A Damms-Machado (BFijo2017225_CR35) 2012; 11 E Le Chatelier (BFijo2017225_CR32) 2013; 500 S Rabot (BFijo2017225_CR40) 2016; 6 N Hariri (BFijo2017225_CR45) 2010; 23 IC de Macedo (BFijo2017225_CR21) 2016; 2016 A Gavrila (BFijo2017225_CR25) 2003; 88 E Oliveros (BFijo2017225_CR19) 2014; 56 BFijo2017225_CR17 L Cordain (BFijo2017225_CR3) 2005; 81 TC Rosini (BFijo2017225_CR34) 2012; 58 S Reardon (BFijo2017225_CR41) 2016; 530 R Buettner (BFijo2017225_CR5) 2007; 15 V Lecomte (BFijo2017225_CR12) 2015; 10 BFijo2017225_CR14 SH Zeisel (BFijo2017225_CR29) 2009; 67 La Adams (BFijo2017225_CR23) 2005; 22 D Grotto (BFijo2017225_CR16) 2010; 25 HR Berthoud (BFijo2017225_CR18) 2012; 107 M Via (BFijo2017225_CR36) 2012; 2012 R Veteläinen (BFijo2017225_CR28) 2007; 22 TS Higa (BFijo2017225_CR8) 2014; 6 PG Reeves (BFijo2017225_CR15) 1993; 123 A Casadevall (BFijo2017225_CR43) 2010; 78 BFijo2017225_CR44 S Bellentani (BFijo2017225_CR22) 2010; 28 JS Teodoro (BFijo2017225_CR27) 2014; 9 BFijo2017225_CR4 AN Thorburn (BFijo2017225_CR20) 2014; 40 AK DeGruttola (BFijo2017225_CR33) 2016; 22 K Brown (BFijo2017225_CR39) 2012; 4 FS Collins (BFijo2017225_CR42) 2014; 505 V Tremaroli (BFijo2017225_CR37) 2012; 489 CL Boulangé (BFijo2017225_CR13) 2016; 8 S Smyth (BFijo2017225_CR2) 2006; 12 J Shen (BFijo2017225_CR10) 2013; 34 BP Sampey (BFijo2017225_CR7) 2011; 19 C Nilsson (BFijo2017225_CR6) 2012; 33 GD Wu (BFijo2017225_CR38) 2011; 334 DW Haslam (BFijo2017225_CR1) 2005; 366 N Ouchi (BFijo2017225_CR24) 2011; 11 BJ Moore (BFijo2017225_CR9) 1987; 117 S Ahmad (BFijo2017225_CR26) 2014; 24 PJ Turnbaugh (BFijo2017225_CR31) 2008; 3 JL Sonnenburg (BFijo2017225_CR11) 2016; 535 O Kucera (BFijo2017225_CR30) 2014; 20 |
| References_xml | – volume: 12 start-page: 75 year: 2006 end-page: 80 ident: CR2 article-title: Diabetes and obesity: the twin epidemics publication-title: Nat Med doi: 10.1038/nm0106-75 contributor: fullname: Heron – volume: 28 start-page: 155 year: 2010 end-page: 161 ident: CR22 article-title: Epidemiology of non-alcoholic fatty liver disease publication-title: Dig Dis doi: 10.1159/000282080 contributor: fullname: Bedogni – volume: 24 start-page: 979 year: 2014 end-page: 990 ident: CR26 article-title: Glycoxidation of biological macromolecules: a critical approach to halt the menace of glycation publication-title: Glycobiology doi: 10.1093/glycob/cwu057 contributor: fullname: Ashraf – volume: 500 start-page: 541 year: 2013 end-page: 546 ident: CR32 article-title: Richness of human gut microbiome correlates with metabolic markers publication-title: Nature doi: 10.1038/nature12506 contributor: fullname: Falony – volume: 505 start-page: 612 year: 2014 end-page: 613 ident: CR42 article-title: NIH plans to enhance reproducibility publication-title: Nature doi: 10.1038/505612a contributor: fullname: Tabak – volume: 78 start-page: 4972 year: 2010 end-page: 4975 ident: CR43 article-title: Reproducible science publication-title: Infect Immun doi: 10.1128/IAI.00908-10 contributor: fullname: Fang – volume: 10 start-page: e0126931 year: 2015 ident: CR12 article-title: Changes in gut microbiota in rats fed a high fat diet correlate with obesity-associated metabolic parameters publication-title: PLoS One doi: 10.1371/journal.pone.0126931 contributor: fullname: Mitchell – ident: CR4 – ident: CR14 – volume: 117 start-page: 227 year: 1987 end-page: 231 ident: CR9 article-title: The cafeteria diet-an inappropriate tool for studies of thermogenesis publication-title: J Nutr doi: 10.1093/jn/117.2.227 contributor: fullname: Moore – volume: 22 start-page: 1526 year: 2007 end-page: 1533 ident: CR28 article-title: Essential pathogenic and metabolic differences in steatosis induced by choline or methione-choline deficient diets in a rat model publication-title: J Gastroenterol Hepatol doi: 10.1111/j.1440-1746.2006.04701.x contributor: fullname: van Gulik – volume: 58 start-page: 383 year: 2012 end-page: 387 ident: CR34 article-title: Diet-induced obesity: rodent model for the study of obesity-related disorders publication-title: Rev Assoc Med Bras contributor: fullname: de Moraes – volume: 81 start-page: 341 year: 2005 end-page: 354 ident: CR3 article-title: Origins and evolution of the Western diet: health implications for the 21st century publication-title: Am J Clin Nutr doi: 10.1093/ajcn.81.2.341 contributor: fullname: Watkins – volume: 2012 start-page: 1 year: 2012 end-page: 8 ident: CR36 article-title: The malnutrition of obesity: micronutrient deficiencies that promote diabetes publication-title: ISRN Endocrinol doi: 10.5402/2012/103472 contributor: fullname: Via – volume: 366 start-page: 1197 year: 2005 end-page: 1209 ident: CR1 article-title: Obesity publication-title: Lancet doi: 10.1016/S0140-6736(05)67483-1 contributor: fullname: James – volume: 11 start-page: 34 year: 2012 ident: CR35 article-title: Micronutrient deficiency in obese subjects undergoing low calorie diet publication-title: Nutr J doi: 10.1186/1475-2891-11-34 contributor: fullname: Bischoff – volume: 4 start-page: 1095 year: 2012 end-page: 1119 ident: CR39 article-title: Diet-induced dysbiosis of the intestinal microbiota and the effects on immunity and disease publication-title: Nutrients doi: 10.3390/nu4081095 contributor: fullname: Gibson – volume: 6 start-page: 47 year: 2014 end-page: 54 ident: CR8 article-title: Evangelista FSA. Comparison between cafeteria and high-fat diets in the induction of metabolic dysfunction in mice publication-title: Int J Physiol Pathophysiol Pharmacol contributor: fullname: Fonseca-Alaniz – volume: 34 start-page: 39 year: 2013 end-page: 58 ident: CR10 article-title: The gut microbiota, obesity and insulin resistance publication-title: Mol Aspects Med doi: 10.1016/j.mam.2012.11.001 contributor: fullname: Zhao – volume: 40 start-page: 833 year: 2014 end-page: 842 ident: CR20 article-title: Diet, metabolites, and ‘western-lifestyle’ inflammatory diseases publication-title: Immunity doi: 10.1016/j.immuni.2014.05.014 contributor: fullname: Mackay – ident: CR44 – volume: 535 start-page: 56 year: 2016 end-page: 64 ident: CR11 article-title: Diet–microbiota interactions as moderators of human metabolism publication-title: Nature doi: 10.1038/nature18846 contributor: fullname: Bäckhed – volume: 33 start-page: 173 year: 2012 end-page: 181 ident: CR6 article-title: Laboratory animals as surrogate models of human obesity publication-title: Acta Pharmacol Sin doi: 10.1038/aps.2011.203 contributor: fullname: Tang-Christensen – volume: 20 start-page: 8364 year: 2014 end-page: 8376 ident: CR30 article-title: Experimental models of non-alcoholic fatty liver disease in rats publication-title: World J Gastroenterol doi: 10.3748/wjg.v20.i26.8364 contributor: fullname: Kucera – volume: 19 start-page: 1109 year: 2011 end-page: 1117 ident: CR7 article-title: Cafeteria diet is a robust model of human metabolic syndrome with liver and adipose inflammation: comparison to high-fat diet publication-title: Obesity doi: 10.1038/oby.2011.18 contributor: fullname: Fueger – volume: 2016 start-page: 1 year: 2016 end-page: 7 ident: CR21 article-title: The influence of palatable diets in reward system activation: a mini review publication-title: Adv Pharmacol Sci doi: 10.1155/2016/7238679 contributor: fullname: da Silva Torres – volume: 22 start-page: 1137 year: 2016 end-page: 1150 ident: CR33 article-title: Current understanding of dysbiosis in disease in human and animal models publication-title: Inflamm Bowel Dis doi: 10.1097/MIB.0000000000000750 contributor: fullname: Mizoguchi – ident: CR17 – volume: 9 start-page: 406 year: 2014 ident: CR27 article-title: High-fat and obesogenic diets: current and future strategies to fight obesity and diabetes publication-title: Genes Nutr doi: 10.1007/s12263-014-0406-6 contributor: fullname: Palmeira – volume: 489 start-page: 242 year: 2012 end-page: 249 ident: CR37 article-title: Functional interactions between the gut microbiota and host metabolism publication-title: Nature doi: 10.1038/nature11552 contributor: fullname: Bäckhed – volume: 22 start-page: 1129 year: 2005 end-page: 1133 ident: CR23 article-title: Recent concepts in non-alcoholic fatty liver disease publication-title: Diabet Med doi: 10.1111/j.1464-5491.2005.01748.x contributor: fullname: Angulo – volume: 334 start-page: 105 year: 2011 end-page: 108 ident: CR38 article-title: Linking long-term dietary patterns with gut microbial enterotypes publication-title: Science doi: 10.1126/science.1208344 contributor: fullname: Keilbaugh – volume: 107 start-page: 527 year: 2012 end-page: 532 ident: CR18 article-title: Modulation of taste responsiveness and food preference by obesity and weight loss publication-title: Physiol Behav doi: 10.1016/j.physbeh.2012.04.004 contributor: fullname: Zheng – volume: 530 start-page: 264 year: 2016 end-page: 264 ident: CR41 article-title: A mouse’s house may ruin experiments publication-title: Nature doi: 10.1038/nature.2016.19335 contributor: fullname: Reardon – volume: 123 start-page: 1939 year: 1993 end-page: 1951 ident: CR15 article-title: AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet publication-title: J Nutr doi: 10.1093/jn/123.11.1939 contributor: fullname: Fahey – volume: 56 start-page: 426 year: 2014 end-page: 433 ident: CR19 article-title: The concept of normal weight obesity publication-title: Prog Cardiovasc Dis doi: 10.1016/j.pcad.2013.10.003 contributor: fullname: Lopez-Jimenez – volume: 3 start-page: 213 year: 2008 end-page: 223 ident: CR31 article-title: Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome publication-title: Cell Host Microbe doi: 10.1016/j.chom.2008.02.015 contributor: fullname: Gordon – volume: 15 start-page: 798 year: 2007 end-page: 808 ident: CR5 article-title: High-fat diets: modeling the metabolic disorders of human obesity in rodents publication-title: Obesity doi: 10.1038/oby.2007.608 contributor: fullname: Bollheimer – volume: 25 start-page: 603 year: 2010 end-page: 612 ident: CR16 article-title: The standard American diet and its relationship to the health status of Americans publication-title: Nutr Clin Pract doi: 10.1177/0884533610386234 contributor: fullname: Zied – volume: 11 start-page: 85 year: 2011 end-page: 97 ident: CR24 article-title: Adipokines in inflammation and metabolic disease publication-title: Nat Rev Immunol doi: 10.1038/nri2921 contributor: fullname: Walsh – volume: 88 start-page: 4823 year: 2003 end-page: 4831 ident: CR25 article-title: Serum adiponectin levels are inversely associated with overall and central fat distribution but are not directly regulated by acute fasting or leptin administration in humans: cross-sectional and interventional studies publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2003-030214 contributor: fullname: Orlova – volume: 8 start-page: 42 year: 2016 ident: CR13 article-title: Impact of the gut microbiota on inflammation, obesity, and metabolic disease publication-title: Genome Med doi: 10.1186/s13073-016-0303-2 contributor: fullname: Dumas – volume: 23 start-page: 270 year: 2010 end-page: 299 ident: CR45 article-title: High-fat diet-induced obesity in animal models publication-title: Nutr Res Rev doi: 10.1017/S0954422410000168 contributor: fullname: Thibault – volume: 6 start-page: 32484 year: 2016 ident: CR40 article-title: High fat diet drives obesity regardless the composition of gut microbiota in mice publication-title: Sci Rep doi: 10.1038/srep32484 contributor: fullname: Krause – volume: 67 start-page: 615 year: 2009 end-page: 623 ident: CR29 article-title: Choline: an essential nutrient for public health publication-title: Nutr Rev doi: 10.1111/j.1753-4887.2009.00246.x contributor: fullname: da Costa – volume: 12 start-page: 75 year: 2006 ident: BFijo2017225_CR2 publication-title: Nat Med doi: 10.1038/nm0106-75 contributor: fullname: S Smyth – volume: 81 start-page: 341 year: 2005 ident: BFijo2017225_CR3 publication-title: Am J Clin Nutr doi: 10.1093/ajcn.81.2.341 contributor: fullname: L Cordain – ident: BFijo2017225_CR4 – volume: 15 start-page: 798 year: 2007 ident: BFijo2017225_CR5 publication-title: Obesity doi: 10.1038/oby.2007.608 contributor: fullname: R Buettner – volume: 123 start-page: 1939 year: 1993 ident: BFijo2017225_CR15 publication-title: J Nutr doi: 10.1093/jn/123.11.1939 contributor: fullname: PG Reeves – volume: 58 start-page: 383 year: 2012 ident: BFijo2017225_CR34 publication-title: Rev Assoc Med Bras contributor: fullname: TC Rosini – volume: 489 start-page: 242 year: 2012 ident: BFijo2017225_CR37 publication-title: Nature doi: 10.1038/nature11552 contributor: fullname: V Tremaroli – volume: 22 start-page: 1129 year: 2005 ident: BFijo2017225_CR23 publication-title: Diabet Med doi: 10.1111/j.1464-5491.2005.01748.x contributor: fullname: La Adams – ident: BFijo2017225_CR44 doi: 10.1126/science.aah7199 – volume: 366 start-page: 1197 year: 2005 ident: BFijo2017225_CR1 publication-title: Lancet doi: 10.1016/S0140-6736(05)67483-1 contributor: fullname: DW Haslam – volume: 22 start-page: 1526 year: 2007 ident: BFijo2017225_CR28 publication-title: J Gastroenterol Hepatol doi: 10.1111/j.1440-1746.2006.04701.x contributor: fullname: R Veteläinen – volume: 6 start-page: 32484 year: 2016 ident: BFijo2017225_CR40 publication-title: Sci Rep doi: 10.1038/srep32484 contributor: fullname: S Rabot – volume: 10 start-page: e0126931 year: 2015 ident: BFijo2017225_CR12 publication-title: PLoS One doi: 10.1371/journal.pone.0126931 contributor: fullname: V Lecomte – ident: BFijo2017225_CR17 – volume: 530 start-page: 264 year: 2016 ident: BFijo2017225_CR41 publication-title: Nature doi: 10.1038/nature.2016.19335 contributor: fullname: S Reardon – volume: 34 start-page: 39 year: 2013 ident: BFijo2017225_CR10 publication-title: Mol Aspects Med doi: 10.1016/j.mam.2012.11.001 contributor: fullname: J Shen – volume: 9 start-page: 406 year: 2014 ident: BFijo2017225_CR27 publication-title: Genes Nutr doi: 10.1007/s12263-014-0406-6 contributor: fullname: JS Teodoro – volume: 11 start-page: 34 year: 2012 ident: BFijo2017225_CR35 publication-title: Nutr J doi: 10.1186/1475-2891-11-34 contributor: fullname: A Damms-Machado – volume: 78 start-page: 4972 year: 2010 ident: BFijo2017225_CR43 publication-title: Infect Immun doi: 10.1128/IAI.00908-10 contributor: fullname: A Casadevall – volume: 40 start-page: 833 year: 2014 ident: BFijo2017225_CR20 publication-title: Immunity doi: 10.1016/j.immuni.2014.05.014 contributor: fullname: AN Thorburn – volume: 4 start-page: 1095 year: 2012 ident: BFijo2017225_CR39 publication-title: Nutrients doi: 10.3390/nu4081095 contributor: fullname: K Brown – volume: 2016 start-page: 1 year: 2016 ident: BFijo2017225_CR21 publication-title: Adv Pharmacol Sci doi: 10.1155/2016/7238679 contributor: fullname: IC de Macedo – volume: 334 start-page: 105 year: 2011 ident: BFijo2017225_CR38 publication-title: Science doi: 10.1126/science.1208344 contributor: fullname: GD Wu – volume: 11 start-page: 85 year: 2011 ident: BFijo2017225_CR24 publication-title: Nat Rev Immunol doi: 10.1038/nri2921 contributor: fullname: N Ouchi – volume: 500 start-page: 541 year: 2013 ident: BFijo2017225_CR32 publication-title: Nature doi: 10.1038/nature12506 contributor: fullname: E Le Chatelier – volume: 107 start-page: 527 year: 2012 ident: BFijo2017225_CR18 publication-title: Physiol Behav doi: 10.1016/j.physbeh.2012.04.004 contributor: fullname: HR Berthoud – volume: 20 start-page: 8364 year: 2014 ident: BFijo2017225_CR30 publication-title: World J Gastroenterol doi: 10.3748/wjg.v20.i26.8364 contributor: fullname: O Kucera – volume: 19 start-page: 1109 year: 2011 ident: BFijo2017225_CR7 publication-title: Obesity doi: 10.1038/oby.2011.18 contributor: fullname: BP Sampey – ident: BFijo2017225_CR14 – volume: 88 start-page: 4823 year: 2003 ident: BFijo2017225_CR25 publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2003-030214 contributor: fullname: A Gavrila – volume: 22 start-page: 1137 year: 2016 ident: BFijo2017225_CR33 publication-title: Inflamm Bowel Dis doi: 10.1097/MIB.0000000000000750 contributor: fullname: AK DeGruttola – volume: 33 start-page: 173 year: 2012 ident: BFijo2017225_CR6 publication-title: Acta Pharmacol Sin doi: 10.1038/aps.2011.203 contributor: fullname: C Nilsson – volume: 2012 start-page: 1 year: 2012 ident: BFijo2017225_CR36 publication-title: ISRN Endocrinol doi: 10.5402/2012/103472 contributor: fullname: M Via – volume: 505 start-page: 612 year: 2014 ident: BFijo2017225_CR42 publication-title: Nature doi: 10.1038/505612a contributor: fullname: FS Collins – volume: 3 start-page: 213 year: 2008 ident: BFijo2017225_CR31 publication-title: Cell Host Microbe doi: 10.1016/j.chom.2008.02.015 contributor: fullname: PJ Turnbaugh – volume: 6 start-page: 47 year: 2014 ident: BFijo2017225_CR8 publication-title: Int J Physiol Pathophysiol Pharmacol contributor: fullname: TS Higa – volume: 117 start-page: 227 year: 1987 ident: BFijo2017225_CR9 publication-title: J Nutr doi: 10.1093/jn/117.2.227 contributor: fullname: BJ Moore – volume: 535 start-page: 56 year: 2016 ident: BFijo2017225_CR11 publication-title: Nature doi: 10.1038/nature18846 contributor: fullname: JL Sonnenburg – volume: 28 start-page: 155 year: 2010 ident: BFijo2017225_CR22 publication-title: Dig Dis doi: 10.1159/000282080 contributor: fullname: S Bellentani – volume: 23 start-page: 270 year: 2010 ident: BFijo2017225_CR45 publication-title: Nutr Res Rev doi: 10.1017/S0954422410000168 contributor: fullname: N Hariri – volume: 24 start-page: 979 year: 2014 ident: BFijo2017225_CR26 publication-title: Glycobiology doi: 10.1093/glycob/cwu057 contributor: fullname: S Ahmad – volume: 67 start-page: 615 year: 2009 ident: BFijo2017225_CR29 publication-title: Nutr Rev doi: 10.1111/j.1753-4887.2009.00246.x contributor: fullname: SH Zeisel – volume: 56 start-page: 426 year: 2014 ident: BFijo2017225_CR19 publication-title: Prog Cardiovasc Dis doi: 10.1016/j.pcad.2013.10.003 contributor: fullname: E Oliveros – volume: 8 start-page: 42 year: 2016 ident: BFijo2017225_CR13 publication-title: Genome Med doi: 10.1186/s13073-016-0303-2 contributor: fullname: CL Boulangé – volume: 25 start-page: 603 year: 2010 ident: BFijo2017225_CR16 publication-title: Nutr Clin Pract doi: 10.1177/0884533610386234 contributor: fullname: D Grotto |
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Obesity is a metabolic disorder that predisposes patients to numerous diseases and has become a major global public-health concern.... Obesity is a metabolic disorder that predisposes patients to numerous diseases and has become a major global public-health concern. Animal models of... Background/Objectives: Obesity is a metabolic disorder that predisposes patients to numerous diseases and has become a major global public-health concern.... Background/Objectives:Obesity is a metabolic disorder that predisposes patients to numerous diseases and has become a major global public-health concern.... BACKGROUND/OBJECTIVESObesity is a metabolic disorder that predisposes patients to numerous diseases and has become a major global public-health concern. Animal... |
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| SubjectTerms | 631/326/41 631/45 692/699/2743/2037 692/699/2743/393 Additives Analysis Animal feeding and feeds Animal models Animals Causes of Diagnosis Diet Diet, High-Fat Diet, Western Disease Models, Animal Dysbacteriosis Dysbiosis - metabolism Epidemiology Fast Foods Food Food processing Gastrointestinal Microbiome - physiology Health Promotion and Disease Prevention High fat diet Internal Medicine Intestinal microflora Low fat diet Male Medicine Medicine & Public Health Metabolic Diseases Metabolic Diseases - metabolism Metabolic disorders Metabolism Microbiota Microbiota (Symbiotic organisms) Minerals Nutrient deficiency Obesity Obesity - metabolism Obesity - microbiology Obesity - physiopathology original-article Pathogenesis Processed foods Public Health Rats Rats, Wistar Risk factors Rodents Vitamins |
| Title | A new animal diet based on human Western diet is a robust diet-induced obesity model: comparison to high-fat and cafeteria diets in term of metabolic and gut microbiota disruption |
| URI | https://link.springer.com/article/10.1038/ijo.2017.225 https://www.ncbi.nlm.nih.gov/pubmed/28895587 https://www.proquest.com/docview/2019427375 https://search.proquest.com/docview/1938187436 |
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