A predator-based psychosocial stress animal model of PTSD in females: Influence of estrous phase and ovarian hormones

Traumatized women are more likely than traumatized men to develop post-traumatic stress disorder (PTSD). Still, the inclusion of females in animal models of PTSD has largely been avoided, likely due to the variable hormone profile of female rodents. Because a valid animal model of PTSD that incorpor...

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Bibliographic Details
Published in:	Hormones and behavior Vol. 115; p. 104564
Main Authors:	Zoladz, Phillip R., D'Alessio, Paul A., Seeley, Sarah L., Kasler, Charis D., Goodman, Cassandra S., Mucher, Kasey E., Allison, Alanis S., Smith, Ian F., Dodson, Jordan L., Stoops, Thorne S., Rorabaugh, Boyd R.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-09-2019
Subjects:	Animal model Animals Anxiety - etiology Anxiety - metabolism Anxiety - physiopathology Behavior, Animal - physiology Disease Models, Animal Estrous Estrous Cycle - metabolism Estrous Cycle - physiology Female Ovariectomy PTSD Rats Rats, Sprague-Dawley Reflex, Startle - physiology Sex differences Stress Stress Disorders, Post-Traumatic - etiology Stress Disorders, Post-Traumatic - metabolism Stress Disorders, Post-Traumatic - physiopathology Stress, Psychological - complications Stress, Psychological - metabolism Stress, Psychological - physiopathology PTSD Animal model Sex differences Estrous Ovariectomy Stress
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