Erythrocyte protoporphyrin test for occupational lead exposure

Determination of erythrocyte protoporphyrin levels was performed in workers who are occupationally exposed to lead. The level of erythrocyte protoporphyrin was easily measured with microsamples of blood by utilizing a fluorescent assay. The log of erythrocyte protoporphyrin level was closely correla...

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Bibliographic Details
Published in:	Archives of environmental health Vol. 30; no. 12; p. 588
Main Authors:	Tomokuni, K, Osaka, I, Ogata, M
Format:	Journal Article
Language:	English
Published:	United States 01-12-1975
Subjects:	Alcohol Drinking Environmental Exposure Erythrocytes - analysis Erythrocytes - enzymology Hematocrit Hemoglobins - analysis Humans Lead Poisoning - blood Lead Poisoning - diagnosis Occupational Diseases - diagnosis Porphobilinogen Synthase - analysis Porphyrins - analysis Protoporphyrins - analysis
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Summary:	Determination of erythrocyte protoporphyrin levels was performed in workers who are occupationally exposed to lead. The level of erythrocyte protoporphyrin was easily measured with microsamples of blood by utilizing a fluorescent assay. The log of erythrocyte protoporphyrin level was closely correlated to blood lead level (r = .72) in lead-exposed workers. The erythrocyte protoporphyrin test is especially useful in the detection of mild increases in blood lead concentration under conditions of occupational exposure.
ISSN:	0003-9896
DOI:	10.1080/00039896.1975.10666785