Practical Use of the Raw Electroencephalogram Waveform During General Anesthesia: The Art and Science

• Published in: Anesthesia and analgesia Vol. 109; no. 2; pp. 539 - 550
• Main Authors: Bennett, Cambell, Voss, Logan J., Barnard, John P. M., Sleigh, James W.
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD International Anesthesia Research Society 01-08-2009; Lippincott Williams & Wilkins
• Subjects: Adjuvants, Anesthesia - pharmacology; Anesthesia; Anesthesia, General; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Anesthetics - pharmacology; Biological and medical sciences; Electroencephalography - drug effects; Electroencephalography - statistics & numerical data; Humans; Medical sciences; Monitoring, Intraoperative; Wakefulness - physiology; Waveform; General anesthesia
• ISSN: 0003-2999; 1526-7598
• DOI: 10.1213/ane.0b013e3181a9fc38

Quantitative electroencephalogram (qEEG) monitors are often used to estimate depth of anesthesia and intraoperative recall during general anesthesia. As with any monitor, the processed numerical output is often misleading and has to be interpreted within a clinical context. For the safe clinical use of these monitors, a clear mental picture of the expected raw electroencephalogram (EEG) patterns, as well as a knowledge of the common EEG artifacts, is absolutely necessary. This has provided the motivation to write this tutorial. We describe, and give examples of, the typical EEG features of adequate general anesthesia, effects of noxious stimulation, and adjunctive drugs. Artifacts are commonly encountered and may be classified as arising from outside the head, from the head but outside the brain (commonly frontal electromyogram), or from within the brain (atypical or pathologic). We include real examples of clinical problem-solving processes. In particular, it is important to realize that an artifactually high qEEG index is relatively common and may result in dangerous anesthetic drug overdose. The anesthesiologist must be certain that the qEEG number is consistent with the apparent state of the patient, the doses of various anesthetic drugs, and the degree of surgical stimulation, and that the qEEG number is consistent with the appearance of the raw EEG signal. Any discrepancy must be a stimulus for the immediate critical examination of the patient’s state using all the available information rather than reactive therapy to “treat” a number.