Peripheral and central proinflammatory cytokine response to a severe acute stressor

The role of proinflammatory cytokines in the response to acute stressor exposure has received recent attention. Exposure to a single session of inescapable shock (IS) induces peripheral and central proinflammatory cytokines. Other stressors also increase expression of proinflammatory cytokine mRNA a...

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Bibliographic Details
Published in:	Brain research Vol. 991; no. 1; pp. 123 - 132
Main Authors:	O'Connor, Kevin A, Johnson, John D, Hansen, Michael K, Wieseler Frank, Julie L, Maksimova, Elena, Watkins, Linda R, Maier, Steven F
Format:	Journal Article
Language:	English
Published:	London Elsevier B.V 21-11-2003 Amsterdam Elsevier New York, NY
Subjects:	Animals Behavioral psychophysiology Biological and medical sciences Brain - metabolism Central nervous system Cytokine Cytokines - metabolism Electroshock Enzyme-Linked Immunosorbent Assay Fundamental and applied biological sciences. Psychology Gene Expression Interleukin Interleukin-1 - physiology Interleukin-6 - physiology Male Miscellaneous Peripheral Nervous System - metabolism Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rat Rats Rats, Sprague-Dawley Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Stress Stress, Psychological - metabolism Time Factors Tumor necrosis factor Tumor Necrosis Factor-alpha - physiology Rat Tumor necrosis factor Interleukin Central nervous system Cytokine Neural basis of behavior Stress Vertebrata Mammalia Acute Animal Rodentia Inflammation
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