A delayed ATP‐elicited K+ current in freshly isolated smooth muscle cells from mouse aorta

Adenosine 5′‐triphosphate (ATP) activated two sequential responses in freshly isolated mouse aortic smooth muscle cells. In the first phase, ATP activated Ca2+‐dependent K+ or Cl− currents and the second phase was the activation of a delayed outward current with a reversal potential of −75.9±1.4 mV....

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Bibliographic Details
Published in:	British journal of pharmacology Vol. 147; no. 1; pp. 45 - 54
Main Authors:	Serir, Karima, Hayoz, Sebastien, Fanchaouy, Mohammed, Bény, Jean‐Louis, Bychkov, Rostislav
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Publishing Ltd 01-01-2006 Nature Publishing Nature Publishing Group
Subjects:	Adenosine Triphosphate - physiology Animals Aorta - cytology Aorta - metabolism Aortic smooth muscle cells ATP, GDPβs Biological and medical sciences Ca2+‐independent K+ current Cells, Cultured intracellular Ca2 Medical sciences Mice Myocytes, Smooth Muscle - metabolism Pharmacology. Drug treatments PLC blocker Potassium - metabolism purine receptors Vasodilation - physiology Purine derivatives Calcium Rodentia Smooth muscle Inorganic element In vitro Artery GDPβs; Ca2+-independent K+ current; purine receptors; PLC blocker Vertebrata Mammalia Mouse Animal Blood vessel Aorta Aortic smooth muscle cells; intracellular Ca2+; ATP Circulatory system Intracellular ATP Potassium Biological receptor
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