A novel biomarker for the detection of esophageal adenocarcinoma

Objectives Proliferating cell nuclear antigen is a component of the DNA synthesome and functions in DNA replication and repair. Our group has recently identified an acidic isoform of proliferating cell nuclear antigen, cancer-specific proliferating cell nuclear antigen, that appears to be present on...

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Bibliographic Details
Published in:	The Journal of thoracic and cardiovascular surgery Vol. 133; no. 1; pp. 82 - 87
Main Authors:	Hammoud, Zane T., MD, Badve, Sunil, MD, Saxena, Romil, MD, Kesler, Kenneth A., MD, Rieger, Karen, MD, Malkas, Linda H., PhD, Hickey, Robert J., PhD
Format:	Journal Article
Language:	English
Published:	United States Mosby, Inc 2007 AATS/WTSA
Subjects:	Adenocarcinoma - chemistry Adenocarcinoma - diagnosis Barrett Esophagus - diagnosis Barrett Esophagus - metabolism Biomarkers - analysis Cardiothoracic Surgery Diagnosis, Differential Esophageal Neoplasms - chemistry Esophageal Neoplasms - diagnosis Esophagus - metabolism Humans Immunohistochemistry Precancerous Conditions - diagnosis Precancerous Conditions - metabolism Proliferating Cell Nuclear Antigen - analysis Protein Isoforms PBS phosphate-buffered saline solution proliferating cell nuclear antigen PCNA polyclonal antibody to cancer-specific proliferating cell nuclear antigen KLH 7 keyhole limpet hemacyanin csPCNAab csPCNA cancer-specific proliferating cell nuclear antigen
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