DNA Building Block Reinvented

DNA Building Block Reinvented

The large number of complete genome sequences are fueling large-scale bioinformatics, structural genomics, and proteomics efforts that promise to accelerate that design of new drugs. Murzin addresses and article by Myllykallio et al, in which they identify a family of enzymes, ThyX, that synthesize...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) Vol. 297; no. 5578; pp. 61 - 62
Main Author: Murzin, Alexey G.
Format: Journal Article
Language:English
Published: Washington American Society for the Advancement of Science 05-07-2002
American Association for the Advancement of Science
The American Association for the Advancement of Science
Subjects:
Biochemistry
Bioinformatics
Deoxyribonucleic acid
DNA
Electronic publishing
Enzymes
Genetics
Genomes
Genomics
Mars
Molecules
Narcotics
Perspectives
Spacecraft
Thymidine
United States
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Summary:The large number of complete genome sequences are fueling large-scale bioinformatics, structural genomics, and proteomics efforts that promise to accelerate that design of new drugs. Murzin addresses and article by Myllykallio et al, in which they identify a family of enzymes, ThyX, that synthesize the essential DNA precursor thymidylate by an alternative pathway.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0036-8075
1095-9203
DOI:10.1126/science.1073910