Identification and First Report of Inonotus (Phellinus) tropicalis as an Etiologic Agent in a Patient with Chronic Granulomatous Disease

• Published in: Journal of Clinical Microbiology Vol. 43; no. 2; pp. 982 - 987
• Main Authors: Sutton, D. A, Thompson, E. H, Rinaldi, M. G, Iwen, P. C, Nakasone, K. K, Jung, H. S, Rosenblatt, H. M, Paul, M. E
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01-02-2005
• Subjects: Adult; Basidiomycota - classification; Basidiomycota - genetics; Basidiomycota - isolation & purification; Biological and medical sciences; Case Reports; DNA, Fungal - analysis; Fundamental and applied biological sciences. Psychology; Granulomatous Disease, Chronic - etiology; Granulomatous Disease, Chronic - microbiology; Humans; Infectious diseases; Male; Medical sciences; Microbiology; Miscellaneous; Molecular Sequence Data; Mycological Typing Techniques; Mycology; Mycoses - complications; Mycoses - microbiology; Phylogeny; Sequence Analysis, DNA; Human; Chronic granulomatous disease; Microbiology; Inonotus; Basidiomycetes; Hemopathy; Identification; Immune deficiency; Genetic disease; Fungi; Phellinus; Wood destroying fungi; Leukocyte disease; Thallophyta
• ISSN: 0095-1137; 1098-660X
• DOI: 10.1128/JCM.43.2.982-987.2005

Although isolates of filamentous basidiomycetes can usually be recognized in a clinical laboratory setting, identification is problematic, as they seldom exhibit diagnostic morphological features formed in nature. This paper is the first report of Inonotus (Phellinus) tropicalis inciting human disease and describes the methods used to support the identification.