Clinical Characteristics and Quality of Life in Adults Initiating Medical Marijuana Treatment

Abstract Introduction: Despite the rising availability and use of medical marijuana (MM) in the USA, little is known about the demographics, clinical characteristics, or quality of life of MM patients. This study describes the demographic characteristics and health-related quality of life (HRQoL) of...

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Published in:	Medical cannabis and cannabinoids Vol. 5; no. 1; pp. 95 - 101
Main Authors:	Buonomano, Lydia S., Mitnick, Matthew M., McCalmont, Thomas R., Syracuse, Paulina, Dugosh, Karen L., Festinger, David S., Lent, Michelle R.
Format:	Journal Article
Language:	English
Published:	Basel, Switzerland S. Karger AG 03-06-2022 Karger Publishers
Subjects:	clinical characteristics health-related quality of life medical marijuana Research Article Medical marijuana Clinical characteristics Health-related quality of life
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Abstract	Abstract Introduction: Despite the rising availability and use of medical marijuana (MM) in the USA, little is known about the demographics, clinical characteristics, or quality of life of MM patients. This study describes the demographic characteristics and health-related quality of life (HRQoL) of MM patients who are initiating treatment in Pennsylvania. Methods: Two-hundred adults naive to MM and referred for any of the 23 state-approved qualifying conditions were recruited at three MM dispensaries in Pennsylvania between September 2020 and March 2021. All participants consented to the study; completed semi-structured interviews that included demographic questionnaires, the Short Form-36 (SF-36), and Generalized Anxiety Disorder-7 (GAD-7); provided height and weight measurements; and allowed access their dispensary medical records. Results: Participants had a mean age of 48.5 ± 15.6 years, predominantly identified as female (67.5%), and were most commonly referred for chronic pain (63.5%) and/or anxiety (58.5%). Additionally, 46.0% were living with obesity as determined by BMI. Relative to a normative sample, participants reported diminished HRQoL in several domains, most notably in role limitations due to physical health (M = 46.0 ± 42.0), role limitations due to emotional problems (M = 52.5 ± 42.3), energy and fatigue (M = 39.8 ± 20.2), and pain (M = 49.4 ± 26.0). Discussion/Conclusion: Patients initiating MM treatment experienced low HRQoL in multiple domains. Future studies could evaluate the relationship between HRQoL and patients’ decisions to pursue MM treatment, as well as changes in HRQoL with MM use over time.
AbstractList	Introduction: Despite the rising availability and use of medical marijuana (MM) in the USA, little is known about the demographics, clinical characteristics, or quality of life of MM patients. This study describes the demographic characteristics and health-related quality of life (HRQoL) of MM patients who are initiating treatment in Pennsylvania. Methods: Two-hundred adults naive to MM and referred for any of the 23 state-approved qualifying conditions were recruited at three MM dispensaries in Pennsylvania between September 2020 and March 2021. All participants consented to the study; completed semi-structured interviews that included demographic questionnaires, the Short Form-36 (SF-36), and Generalized Anxiety Disorder-7 (GAD-7); provided height and weight measurements; and allowed access their dispensary medical records. Results: Participants had a mean age of 48.5 ± 15.6 years, predominantly identified as female (67.5%), and were most commonly referred for chronic pain (63.5%) and/or anxiety (58.5%). Additionally, 46.0% were living with obesity as determined by BMI. Relative to a normative sample, participants reported diminished HRQoL in several domains, most notably in role limitations due to physical health (M = 46.0 ± 42.0), role limitations due to emotional problems (M = 52.5 ± 42.3), energy and fatigue (M = 39.8 ± 20.2), and pain (M = 49.4 ± 26.0). Discussion/Conclusion: Patients initiating MM treatment experienced low HRQoL in multiple domains. Future studies could evaluate the relationship between HRQoL and patients’ decisions to pursue MM treatment, as well as changes in HRQoL with MM use over time. IntroductionDespite the rising availability and use of medical marijuana (MM) in the USA, little is known about the demographics, clinical characteristics, or quality of life of MM patients. This study describes the demographic characteristics and health-related quality of life (HRQoL) of MM patients who are initiating treatment in Pennsylvania. MethodsTwo-hundred adults naive to MM and referred for any of the 23 state-approved qualifying conditions were recruited at three MM dispensaries in Pennsylvania between September 2020 and March 2021. All participants consented to the study; completed semi-structured interviews that included demographic questionnaires, the Short Form-36 (SF-36), and Generalized Anxiety Disorder-7 (GAD-7); provided height and weight measurements; and allowed access their dispensary medical records. ResultsParticipants had a mean age of 48.5 ± 15.6 years, predominantly identified as female (67.5%), and were most commonly referred for chronic pain (63.5%) and/or anxiety (58.5%). Additionally, 46.0% were living with obesity as determined by BMI. Relative to a normative sample, participants reported diminished HRQoL in several domains, most notably in role limitations due to physical health (M = 46.0 ± 42.0), role limitations due to emotional problems (M = 52.5 ± 42.3), energy and fatigue (M = 39.8 ± 20.2), and pain (M = 49.4 ± 26.0). Discussion/ConclusionPatients initiating MM treatment experienced low HRQoL in multiple domains. Future studies could evaluate the relationship between HRQoL and patients' decisions to pursue MM treatment, as well as changes in HRQoL with MM use over time. Abstract Introduction: Despite the rising availability and use of medical marijuana (MM) in the USA, little is known about the demographics, clinical characteristics, or quality of life of MM patients. This study describes the demographic characteristics and health-related quality of life (HRQoL) of MM patients who are initiating treatment in Pennsylvania. Methods: Two-hundred adults naive to MM and referred for any of the 23 state-approved qualifying conditions were recruited at three MM dispensaries in Pennsylvania between September 2020 and March 2021. All participants consented to the study; completed semi-structured interviews that included demographic questionnaires, the Short Form-36 (SF-36), and Generalized Anxiety Disorder-7 (GAD-7); provided height and weight measurements; and allowed access their dispensary medical records. Results: Participants had a mean age of 48.5 ± 15.6 years, predominantly identified as female (67.5%), and were most commonly referred for chronic pain (63.5%) and/or anxiety (58.5%). Additionally, 46.0% were living with obesity as determined by BMI. Relative to a normative sample, participants reported diminished HRQoL in several domains, most notably in role limitations due to physical health (M = 46.0 ± 42.0), role limitations due to emotional problems (M = 52.5 ± 42.3), energy and fatigue (M = 39.8 ± 20.2), and pain (M = 49.4 ± 26.0). Discussion/Conclusion: Patients initiating MM treatment experienced low HRQoL in multiple domains. Future studies could evaluate the relationship between HRQoL and patients’ decisions to pursue MM treatment, as well as changes in HRQoL with MM use over time.
Author	Festinger, David S. Mitnick, Matthew M. Buonomano, Lydia S. McCalmont, Thomas R. Dugosh, Karen L. Syracuse, Paulina Lent, Michelle R.
AuthorAffiliation	b Public Health Management Corporation, Research and Evaluation Group, Philadelphia, Pennsylvania, USA a School of Professional and Applied Psychology, Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, USA
AuthorAffiliation_xml	– name: a School of Professional and Applied Psychology, Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, USA – name: b Public Health Management Corporation, Research and Evaluation Group, Philadelphia, Pennsylvania, USA
Author_xml	– sequence: 1 givenname: Lydia S. surname: Buonomano fullname: Buonomano, Lydia S. – sequence: 2 givenname: Matthew M. surname: Mitnick fullname: Mitnick, Matthew M. – sequence: 3 givenname: Thomas R. surname: McCalmont fullname: McCalmont, Thomas R. – sequence: 4 givenname: Paulina surname: Syracuse fullname: Syracuse, Paulina – sequence: 5 givenname: Karen L. orcidid: 0000-0001-8496-2562 surname: Dugosh fullname: Dugosh, Karen L. – sequence: 6 givenname: David S. surname: Festinger fullname: Festinger, David S. – sequence: 7 givenname: Michelle R. surname: Lent fullname: Lent, Michelle R. email: *Michelle R. Lent, michellele@pcom.edu
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Cites_doi	10.1001/archinte.166.10.1092 10.1038/nrn3530 10.1016/j.drugalcdep.2017.03.009 10.1001/jama.2015.6199 10.1097/YCO.0000000000000566 10.1016/s1550-8579(07)80057-x 10.1097/CAD.0000000000000685 10.4088/JCP.15r10036 10.1159/000512342 10.1002/hec.3267 10.1177/1049909112454215 10.1001/jamaoncol.2016.0155 10.1089/jwh.2020.8437 10.1002/da.22664 10.1080/02791072.2011.587700 10.1097/00005650-199206000-00002 10.1093/ecam/nen023
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References	Bar-Sela G, Tauber D, Mitnik I, Sheinman-Yuffe H, Bishara-Frolova T, Aharon-Peretz J. Cannabis-related cognitive impairment: a prospective evaluation of possible influences on patients with cancer during chemotherapy treatment as a pilot study. Anticancer Drugs. 2019;30(1):91–7. Pennsylvania Department of Health. Medical marijuana two-year final report. 2020 May. Available from: https://www.health.pa.gov/topics/Documents/Programs/Medical%20Marijuana/DOH%20MM%20Official%20Two%20Year%20Report%20-%20May%2015%202020.pdf. Wilkie G, Sakr B, Rizack T. Medical marijuana use in oncology: a review. JAMA Oncol. 2016;2(5):670–5. Aggarwal SK, Carter GT, Sullivan MD, Zumbrunnen C, Morrill R, Mayer JD. Prospectively surveying health-related quality of life and symptom relief in a lot-based sample of medical cannabis-using patients in urban Washington State reveals managed chronic illness and debility. Am J Hosp Palliat Care. 2013;30(6):523–31. Adams D, Ofei-Tenkorang NA, Connell P, Owens A, Gothard A, Souza D, . Interests and concerns regarding medical marijuana among chronic pain patients in Ohio: an online survey. J Cannabis Res. 2021;3(1):37. Tsang A, Von Korff M, Lee S, Alonso J, Karam E, Angermeyer MC, . Common chronic pain conditions in developed and developing countries: gender and age differences and comorbidity with depression-anxiety disorders. J Pain. 2008;9(10):883–91. Sabia JJ, Swigert J, Young T. The effect of medical marijuana laws on body weight. Health Econ. 2017;26(1):6–34. Hanson K, Garcia A. State medical cannabis laws. 2022. Ncsl.org. Available from: https://www.ncsl.org/research/health/state-medical-marijuana-laws.aspx. Bruce D, Grove TJ, Foster E, Shattell M. Gender differences in medical cannabis use: symptoms treated, physician support for use, and prescription medication discontinuation. J Womens Health. 2021;30(6):857–63. Smith A. Marijuana as a schedule I substance: political ploy or accepted science. Santa Clara Law Rev. 2000;40(4):1137. Available from: http://digitalcommons.law.scu.edu/lawreview/vol40/iss4/8. Ilgen MA, Bohnert K, Kleinberg F, Jannausch M, Bohnert ASB, Walton M, . Characteristics of adults seeking medical marijuana certification. Drug Alcohol Depend. 2013;132(3):654–9. Rosenthal MS, Pipitone RN. Demographics, perceptions, and use of medical marijuana among patients in Florida. Med Cannabis Cannabinoids. 2021;4(1):13–20. Bekker MH, van Mens-Verhulst J. Anxiety disorders: sex differences in prevalence, degree, and background, but gender-neutral treatment. Gend Med. 2007;4 Suppl B:S178–93. D’Souza DC, Ranganathan M. Medical marijuana: is the cart before the horse. JAMA. 2015;313(24):2431–2. Bishop FL, Lewith GT. Who uses CAM? A narrative review of demographic characteristics and health factors associated with CAM use. Evid Based Complement Alternat Med. 2010;7(1):11–28. Wilkinson ST, Radhakrishnan R, D’Souza DC. A systematic review of the evidence for medical marijuana in psychiatric indications. J Clin Psychiatry. 2016;77(8):1050–64. Ware JEJr, SherbourneCD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992;30(6):473–83. Spitzer RL, Kroenke K, Williams JB, Löwe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006;166(10):1092–7. Nutt DJ, King LA, Nichols DE. Effects of schedule I drug laws on neuroscience research and treatment innovation. Nat Rev Neurosci. 2013;14(8):577–85. Van Ameringen M, Zhang J, Patterson B, Turna J. The role of cannabis in treating anxiety: an update. Curr Opin Psychiatry. 2020;33(1):1–7. Reinarman C, Nunberg H, Lanthier F, Heddleston T. Who are medical marijuana patients? Population characteristics from nine California assessment clinics. J Psychoactive Drugs. 2011;43(2):128–35. Julayanont P, Tangwongchai S, Hemrungrojn S, Tunvirachaisakul C, Phanthumchinda K, Hongsawat J, . The montreal cognitive assessment-basic: a screening tool for mild cognitive impairment in illiterate and low-educated elderly adults. J Am Geriatr Soc. 2015;63(12):2550–4. Hales CM, Carroll MD, Fryar CD, Ogden CL. Prevalence of obesity and severe obesity among adults: United States, 2017–2018. 2020. Cdc.gov. Available from: https://www.cdc.gov/nchs/products/databriefs/db360.htm#:∼:text=From%201999%E2%80%932000%20through%202017%E2%80%932018%2C%20the%20age%2D,not%20significant%20(Figure%204). LeResche L, Saunders K, Dublin S, Thielke S, Merrill JO, Shortreed SM, . Sex and age differences in global pain status among patients using opioids long term for chronic noncancer pain. J Womens Health. 2015;24(8):629–35. Park JY, Wu LT. Prevalence, reasons, perceived effects, and correlates of medical marijuana use: a review. Drug Alcohol Depend. 2017;177:1–13. Turna J, Patterson B, Van Ameringen M. Is cannabis treatment for anxiety, mood, and related disorders ready for prime time. Depress Anxiety. 2017;34(11):1006–17. Hill KP. Medical marijuana for treatment of chronic pain and other medical and psychiatric problems: a clinical review. JAMA. 2015 Jun 23–30;313(24):2474–83. ref13 ref12 ref15 ref14 ref11 ref10 ref2 ref1 ref17 ref16 ref8 ref7 ref9 ref4 ref3 ref6 ref5
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Snippet	Abstract Introduction: Despite the rising availability and use of medical marijuana (MM) in the USA, little is known about the demographics, clinical... Introduction: Despite the rising availability and use of medical marijuana (MM) in the USA, little is known about the demographics, clinical characteristics,... IntroductionDespite the rising availability and use of medical marijuana (MM) in the USA, little is known about the demographics, clinical characteristics, or...
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Title	Clinical Characteristics and Quality of Life in Adults Initiating Medical Marijuana Treatment
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