Development and characterization of a clinically relevant mouse model of melanoma brain metastasis

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Bibliographic Details
Published in:	Pigment cell and melanoma research Vol. 26; no. 5; pp. 743 - 745
Main Authors:	Morsi, Amr, Gaziel-Sovran, Avital, Cruz-Munoz, William, Kerbel, Robert S., Golfinos, John G., Hernando, Eva, Wadghiri, Youssef Z.
Format:	Journal Article
Language:	English
Published:	England Blackwell Publishing Ltd 01-09-2013 Wiley Subscription Services, Inc
Subjects:	Animals Brain Neoplasms - pathology Brain Neoplasms - secondary Cell Line, Tumor Disease Models, Animal Humans Magnetic Resonance Imaging Melanoma - pathology Melanoma, Experimental - pathology Mice Mice, Inbred C57BL Ultrasonics
Online Access:	Get full text
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Bibliography:	Career Development Award of the Melanoma Research Foundation ArticleID:PCMR12114 Data S1. Commercially available mouse body MRI probe for simultaneous ex vivo MR imaging of four whole heads. Data S2. Ex vivo MR imaging protocol used for four whole heads imaging. Data S3. Ultrasound-guided intracardiac injection. Data S4. Morbidity of intracardiac injection versus intracarotid injection. Data S5. Differences in tissue tropism between B16F10 and 5B1 melanoma cell lines. Data S6. Differences in metastatic behavior between B16F10 and 5B1 melanoma cell lines. Data S7. Ex vivo MRI revealed characteristic radiological features of melanoma brain metastasis. Data S8. Differences in site-specific metastasis between B16F10 and 5B1 cell lines. Data S9. Ex vivo MRI and 3D volumetric studies reveal differences in brain metastasis growth pattern between B16F10 and 5B1 cell lines. Data S10. Segmentation, volumetry, and three-dimensional (3D) rendering of brain tumor datasets from 5B1/athymic/nude and B16F10/C57Bl/6 mouse model. istex:F608CEFF67FE7B7C6DD5BFE0E3F809F85BB594D3 National Cancer Institute ark:/67375/WNG-2SM5RFV3-Q Department of Defense (DOD) - No. CA093471; No. 5P30CA016087-32 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1755-1471 1755-148X
DOI:	10.1111/pcmr.12114