The role of microarray technologies in the study of soft tissue tumours

Array technologies (gene array, tissue microarray and others) are being used in a growing number of research projects involving soft tissue tumours. Gene array techniques allow for measurements of RNA expression levels or gene copy number changes for a large number of genes in a single specimen. A c...

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Published in:	Histopathology Vol. 48; no. 1; pp. 22 - 31
Main Authors:	West, R B, Van De Rijn, M
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Science Ltd 01-01-2006 Blackwell
Subjects:	Biological and medical sciences Cluster Analysis gene array Gene Expression Profiling Humans Investigative techniques, diagnostic techniques (general aspects) Medical sciences Microarray Analysis - methods Oligonucleotide Array Sequence Analysis - methods Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques sarcomas Soft Tissue Neoplasms - diagnosis Soft Tissue Neoplasms - genetics soft tissue tumours tissue microarray Anatomic pathology Gene Sarcoma gene array soft tissue tumours Technology Tissue microarrays tissue microarray Genetics Soft tissue Malignant tumor sarcomas
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Abstract	Array technologies (gene array, tissue microarray and others) are being used in a growing number of research projects involving soft tissue tumours. Gene array techniques allow for measurements of RNA expression levels or gene copy number changes for a large number of genes in a single specimen. A complementary technique, tissue microarrays, allows for the measurement of expression of a single gene in a large number of specimens. These techniques and similar ones have created a fundamentally new approach to the investigation of soft tissue tumours. This review addresses some of the advantages, problems, and solutions to those problems that come with these technologies.
AbstractList	Array technologies (gene array, tissue microarray and others) are being used in a growing number of research projects involving soft tissue tumours. Gene array techniques allow for measurements of RNA expression levels or gene copy number changes for a large number of genes in a single specimen. A complementary technique, tissue microarrays, allows for the measurement of expression of a single gene in a large number of specimens. These techniques and similar ones have created a fundamentally new approach to the investigation of soft tissue tumours. This review addresses some of the advantages, problems, and solutions to those problems that come with these technologies.
Author	West, R B Van De Rijn, M
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Snippet	Array technologies (gene array, tissue microarray and others) are being used in a growing number of research projects involving soft tissue tumours. Gene array...
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SubjectTerms	Biological and medical sciences Cluster Analysis gene array Gene Expression Profiling Humans Investigative techniques, diagnostic techniques (general aspects) Medical sciences Microarray Analysis - methods Oligonucleotide Array Sequence Analysis - methods Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques sarcomas Soft Tissue Neoplasms - diagnosis Soft Tissue Neoplasms - genetics soft tissue tumours tissue microarray
Title	The role of microarray technologies in the study of soft tissue tumours
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