Altered Plasma Mitochondrial Metabolites in Persistently Symptomatic Individuals after a GBCA-Assisted MRI

Despite the impressive safety of gadolinium (Gd)-based contrast agents (GBCAs), a small number of patients report the onset of new, severe, ongoing symptoms after even a single exposure-a syndrome termed Gadolinium Deposition Disease (GDD). Mitochondrial dysfunction and oxidative stress have been re...

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Bibliographic Details
Published in:	Toxics (Basel) Vol. 10; no. 2; p. 56
Main Authors:	Denmark, DeAunne, Ruhoy, Ilene, Wittmann, Bryan, Ashki, Haleh, Koran, Lorrin M
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 26-01-2022 MDPI
Subjects:	Apoptosis Chromatography Contrast agents Contrast media Criteria Gadolinium gadolinium-based contrast agents (GBCAs) Magnetic resonance imaging Markers Mass spectroscopy Medical laboratories Metabolism Metabolites Metabolomics Mitochondria mitochondrial disease Nucleotides Oxidative stress Pain Patients Phenotypes Plasma Retention Signs and symptoms Toxicity Urine gadolinium-based contrast agents (GBCAs) metabolomics mitochondrial disease oxidative stress gadolinium
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