Molecular Evidence for Multifocal Papillary Serous Carcinoma of the Peritoneum in Patients With Germline BRCA1 Mutations

Papillary serous carcinoma of the peritoneum (PSCP) diffusely involves peritoneal surfaces, while it spares or only superficially involves the ovaries. PSCP is histologically indistinguishable from serous epithelial ovarian carcinoma, and it may develop years after oophorectomy. The molecular pathog...

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Bibliographic Details
Published in:	JNCI : Journal of the National Cancer Institute Vol. 90; no. 11; pp. 841 - 845
Main Authors:	Schorge, John O., Muto, Michael G., Welch, William R., Bandera, Christina A., Rubin, Stephen C., Bell, Debra A., Berkowitz, Ross S., Mok, Samuel C.
Format:	Journal Article
Language:	English
Published:	Cary, NC Oxford University Press 03-06-1998 Oxford Publishing Limited (England)
Subjects:	Abdomen Adult Aged Aged, 80 and over Alleles Biological and medical sciences Biomarkers, Tumor - genetics Clone Cells - ultrastructure Cystadenocarcinoma, Papillary - genetics Cystadenocarcinoma, Papillary - pathology Disease Susceptibility DNA Methylation DNA, Neoplasm - genetics Dosage Compensation, Genetic Female Gastroenterology. Liver. Pancreas. Abdomen Genes, BRCA1 Genes, p53 Genetic Markers Genetics Humans Loss of Heterozygosity Medical research Medical sciences Middle Aged Molecular biology Mutation Neoplastic Stem Cells - ultrastructure Neoplastic Syndromes, Hereditary - genetics Neoplastic Syndromes, Hereditary - pathology Ovarian cancer Ovariectomy Ovary - embryology Peritoneal Neoplasms - genetics Peritoneal Neoplasms - pathology Peritoneum - embryology Receptors, Androgen - genetics Retrospective Studies Trinucleotide Repeats Tumors X Chromosome - genetics Human Papillary carcinoma Androgen Abdominal disease Exploration Malignant tumor Mutation Peritoneum Hormonal receptor
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