$A phase II trial with anti-Lewis-Y monoclonal antibody (hu3S193) for the treatment of platinum resistant/refractory ovarian, fallopian tube and primary peritoneal carcinoma$
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A phase II trial with anti-Lewis-Y monoclonal antibody (hu3S193) for the treatment of platinum resistant/refractory ovarian, fallopian tube and primary peritoneal carcinoma

Abstract Objectives The primary objective was to evaluate the clinical efficacy of hu3S193, a humanized monoclonal antibody against the Lewis-Y antigen, in patients with platinum resistant/refractory ovarian, fallopian tube and primary peritoneal carcinoma. Secondary objectives were safety and pharm...

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Bibliographic Details
Published in:	Gynecologic oncology Vol. 138; no. 2; pp. 272 - 277
Main Authors:	Smaletz, Oren, Diz, Maria D.P.E, do Carmo, Claudio C, Sabbaga, Jorge, Cunha-Junior, Geraldo F, Azevedo, Sergio J, Maluf, Fernando C, Barrios, Carlos H, Costa, Ronaldo L, Fontana, Ana G, Madrigal, Vivian, Wainstein, Alberto J, Yeda, Fernanda P, Alves, Venâncio A, Moro, Ana M, Blasbalg, Roberto, Scott, Andrew M, Hoffman, Eric W
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-08-2015
Subjects:	Adult Aged Anti Lewis-Y monoclonal antibody (hu3S193) Antibodies, Monoclonal, Humanized - administration & dosage Antibodies, Monoclonal, Humanized - adverse effects Antibodies, Monoclonal, Humanized - immunology Antibodies, Monoclonal, Humanized - pharmacokinetics Carcinoma, Ovarian Epithelial Disease-Free Survival Drug Resistance, Neoplasm Fallopian Tube Neoplasms - immunology Fallopian Tube Neoplasms - metabolism Fallopian Tube Neoplasms - therapy Female Hematology, Oncology and Palliative Medicine Humans Lewis Blood-Group System - immunology Middle Aged Neoplasms, Glandular and Epithelial - immunology Neoplasms, Glandular and Epithelial - metabolism Neoplasms, Glandular and Epithelial - therapy Obstetrics and Gynecology Organoplatinum Compounds - pharmacology Ovarian Neoplasms - immunology Ovarian Neoplasms - metabolism Ovarian Neoplasms - therapy Peritoneal Neoplasms - immunology Peritoneal Neoplasms - metabolism Peritoneal Neoplasms - therapy platinum resistant/refractory ovarian cancer Young Adult Anti Lewis-Y monoclonal antibody (hu3S193) platinum resistant/refractory ovarian cancer
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