Synthesis and antioxidant activity of new C-3 sulfenyl indoles
A convenient and efficient methodology for the synthesis of new C-3 sulfur-substituted indoles under CeCl3·7H2O promotion is reported. Model bis(indol-3-yl)sulfide 4a and bis(indol-3-yl)sulfone 5a proved to display potent antioxidant activity at the low micromolar level, in DPPH, ABTS, and FRAP assa...
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Published in: | Tetrahedron letters Vol. 54; no. 36; pp. 4926 - 4929 |
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Main Authors: | , , , , , |
Format: | Journal Article |
Language: | English |
Published: |
Elsevier Ltd
01-09-2013
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Subjects: | |
Online Access: | Get full text |
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Summary: | A convenient and efficient methodology for the synthesis of new C-3 sulfur-substituted indoles under CeCl3·7H2O promotion is reported. Model bis(indol-3-yl)sulfide 4a and bis(indol-3-yl)sulfone 5a proved to display potent antioxidant activity at the low micromolar level, in DPPH, ABTS, and FRAP assays, as well as in the inhibition of the peroxidation of linoleic acid. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0040-4039 1873-3581 |
DOI: | 10.1016/j.tetlet.2013.07.004 |