Distribution of messenger RNAs for the orphan nuclear receptors Nurr1 and Nur77 ( NGFI-B) in adult rat brain using in situ hybridization

Nurr1 and Nur77 ( NGFI-B) are orphan nuclear receptors, belonging to the steroid/thyroid hormone receptor gene superfamily. They have conserved amino acid sequence in the zinc-finger DNA binding domains and similar COOH-terminal regions, but have no known ligands. However, different expression patte...

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Bibliographic Details
Published in:	Neuroscience Vol. 75; no. 1; pp. 221 - 230
Main Authors:	Xiao, Q, Castillo, S.O, Nikodem, V.M
Format:	Journal Article
Language:	English
Published:	Oxford Elsevier Ltd 01-11-1996 Elsevier
Subjects:	Anatomy Animals Biological and medical sciences brain Brain Chemistry Central nervous system DNA-Binding Proteins - biosynthesis DNA-Binding Proteins - genetics expression Fundamental and applied biological sciences. Psychology Gene Expression Regulation immediate early genes In Situ Hybridization Nerve Tissue Proteins - biosynthesis Nerve Tissue Proteins - genetics Nuclear Receptor Subfamily 4, Group A, Member 1 Nuclear Receptor Subfamily 4, Group A, Member 2 Organ Specificity Rats Receptors, Cytoplasmic and Nuclear Receptors, Steroid Reproducibility of Results RNA, Messenger - analysis Sensitivity and Specificity Transcription Factors - biosynthesis Transcription Factors - genetics Vertebrates: nervous system and sense organs expression PBS, phosphate-buffered saline IEG, immediate early gene NGFI-B, nerve growth factor inducible B gene immediate early genes SSC, standard saline citrate brain Molecular hybridization Vertebrata Nuclear receptor Mammalia Rat Rodentia Central nervous system Distribution Gene expression Brain (vertebrata) Immediate early gene
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