Proteins that bind regulatory regions identified by histone modification chromatin immunoprecipitations and mass spectrometry

The locations of transcriptional enhancers and promoters were recently mapped in many mammalian cell types. Proteins that bind those regulatory regions can determine cell identity but have not been systematically identified. Here we purify native enhancers, promoters or heterochromatin from embryoni...

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Bibliographic Details
Published in:	Nature communications Vol. 6; no. 1; p. 7155
Main Authors:	Engelen, Erik, Brandsma, Johannes H., Moen, Maaike J., Signorile, Luca, Dekkers, Dick H. W., Demmers, Jeroen, Kockx, Christel E. M., Ozgür, Zehila, van IJcken, Wilfred F. J., van den Berg, Debbie L. C., Poot, Raymond A.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 20-05-2015 Nature Publishing Group Nature Pub. Group
Subjects:	631/136/532/2064/2117 631/1647/2217/2088 631/1647/296 631/208/726/2102 82 82/58 Animals Binding Sites Catalytic Domain Chromatin Immunoprecipitation - methods Embryonic Stem Cells - cytology Enhancer Elements, Genetic Genome Histone Code Histones - chemistry Humanities and Social Sciences Kruppel-Like Transcription Factors - chemistry Mass Spectrometry - methods Mice multidisciplinary N-Myc Proto-Oncogene Protein Nuclear Proteins - chemistry Octamer Transcription Factor-3 - metabolism Pluripotent Stem Cells - cytology Promoter Regions, Genetic Protein Binding Proto-Oncogene Proteins - chemistry Receptors, Estrogen - chemistry Regulatory Sequences, Nucleic Acid Reproducibility of Results Science Science (multidisciplinary)
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