Migraine photophobia originating in cone-driven retinal pathways

Migraine headache is uniquely exacerbated by light. Using psychophysical assessments in patients with normal eyesight we found that green light exacerbates migraine headache significantly less than white, blue, amber or red lights. To delineate mechanisms, we used electroretinography and visual evok...

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Bibliographic Details
Published in:	Brain (London, England : 1878) Vol. 139; no. Pt 7; pp. 1971 - 1986
Main Authors:	Noseda, Rodrigo, Bernstein, Carolyn A, Nir, Rony-Reuven, Lee, Alice J, Fulton, Anne B, Bertisch, Suzanne M, Hovaguimian, Alexandra, Cestari, Dean M, Saavedra-Walker, Rodrigo, Borsook, David, Doran, Bruce L, Buettner, Catherine, Burstein, Rami
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01-07-2016
Subjects:	Adolescent Adult Animals Electroretinography - methods Evoked Potentials, Visual - physiology Female Humans Male Middle Aged Migraine Disorders - complications Migraine Disorders - physiopathology Neurons - physiology Original Photic Stimulation Photophobia - etiology Photophobia - physiopathology Rats Rats, Sprague-Dawley Retinal Cone Photoreceptor Cells - physiology Thalamus - physiopathology Visual Pathways - physiopathology Young Adult pain headache electroretinography thalamus visual evoked potential
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