Elevated Fatty Acid Ethyl Esters in Meconium of Sheep Fetuses Exposed In Utero to Ethanol—A New Animal Model

Specific fatty acid ethyl esters (FAEE) in meconium of newborns have been shown to correlate with maternal ethanol exposure. An animal model is needed to assess the validity of this biomarker. We hypothesized that the pregnant/fetal sheep is a feasible animal model for validating FAEE as a biomarker...

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Bibliographic Details
Published in:	Pediatric research Vol. 63; no. 2; pp. 164 - 168
Main Authors:	Littner, Yoav, Cudd, Timothy A, O'Riordan, Mary A, Cwik, Andrew, Bearer, Cynthia F
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01-02-2008 Lippincott Williams & Wilkins
Subjects:	Animals Area Under Curve Biological and medical sciences Disease Models, Animal Esters - metabolism Ethanol - toxicity Fatty Acids - metabolism Female Fetal Alcohol Spectrum Disorders - metabolism General aspects Maternal Exposure Meconium - metabolism Medical sciences Medicine Medicine & Public Health Oleic Acids - chemistry Pediatric Surgery Pediatrics Pregnancy Pregnancy, Animal Sheep Sheep, Domestic translational-investigation Animal model Pediatrics Ethanol Fatty ester Lipids Fatty acids In utero Alcoholic beverage Vertebrata Mammalia Animal Meconium Fetus Sheep Artiodactyla Ungulata
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