Some operations research methods for analyzing protein sequences and structures

• Published in: Annals of operations research Vol. 175; no. 1; pp. 9 - 35
• Main Authors: Lukasiak, Piotr, Blazewicz, Jacek, Mitostan, Maciej
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01-03-2010; Springer; Springer Nature B.V
• Subjects: Amino acids; Bioinformatics; Biology; Business and Management; Chromosomes; Clustering; Combinatorics; Computer science; Deoxyribonucleic acid; DNA; Dynamic programming; Enzymes; Genes; Genetic engineering; Genomes; Methods; Molecular biology; Neural networks; Operations research; Operations Research/Decision Theory; Protein synthesis; Proteins; Research methodology; Ribonucleic acid; RNA; Scientists; Studies; Theory of Computation; Transfer RNA; Hidden Markov model; Dynamic programming; Clustering; Neural networks; Protein structure
• ISSN: 0254-5330; 1572-9338
• DOI: 10.1007/s10479-009-0652-y

The operations research is probably one of the most successful field of applied mathematics used in economics, physics, chemistry, almost everywhere where one has to analyze huge amounts of data. Lately, these techniques of operations research were introduced in biology, especially in the protein analysis area to support biologists. The fast growth of protein data makes operations research an important issue in bioinformatics, a science which lays on the border between computer science and biology. This paper gives a short overview of the operations research techniques currently used to support structural and functional analysis of proteins.