ALTERNATE COEXISTENCE OF NADPH-DIAPHORASE WITH CHOLINE ACETYLTRANSFERASE OR SOMATOSTATIN IN THE RAT NEOSTRIATUM AND BASAL FOREBRAIN

• Published in: ACTA HISTOCHEMICA ET CYTOCHEMICA Vol. 22; no. 6; pp. 669 - 674
• Main Authors: SCHOBER, ANDREAS, BRAUER, KURT, LUPPA, HANS
• Format: Journal Article
• Language: English
• Published: Kyoto JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY 01-01-1989; Japan Society of Histochemistry and Cytochemistry; Japan Science and Technology Agency
• Subjects: Analytical, structural and metabolic biochemistry; Biological and medical sciences; Enzymes and enzyme inhibitors; Fundamental and applied biological sciences. Psychology; Oxidoreductases; Brain; Rat; Enzyme; Rodentia; Choline acetyltransferase; NADPH dehydrogenase; Immunological method; Vertebrata; Optical microscopy; Mammalia; Localization; Comparative study; Histochemistry
• ISSN: 0044-5991; 1347-5800
• DOI: 10.1267/ahc.22.669

The coexistence of reduced nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) with somatostatin (SOM) and choline acetyltransferase (ChAT) was compared between the rat neostriatum (ST) and basal forebrain complex (BF) . NADPH-d coexists with SOM in ST, but not in the ventral pallidum (VP), in the substantia innominata-nucleus basalis complex (SI-NB) and in the magnocellular preoptic nucleus (NPM) of the BF. In the medial septal nucleus as well as in the vertical and the horizontal limbs of the diagonal band (MS-vDB, hDB) representing the rostral BF and in the SI-NB, a high number of ChAT-positive cells also contain NADPH-d. The NPM shows a smaller number of double-stained cholinergic neurons. The functional significance of the NADPH-d coexistence in BF cholinergic cells is still unknown.