ORP5 localizes to ER-lipid droplet contacts and regulates the level of PI(4)P on lipid droplets

Lipid droplets (LDs) are evolutionarily conserved organelles that play important roles in cellular metabolism. Each LD is enclosed by a monolayer of phospholipids, distinct from bilayer membranes. During LD biogenesis and growth, this monolayer of lipids expands by acquiring phospholipids from the e...

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Bibliographic Details
Published in:	The Journal of cell biology Vol. 219; no. 1; p. 1
Main Authors:	Du, Ximing, Zhou, Linkang, Aw, Yvette Celine, Mak, Hoi Yin, Xu, Yanqing, Rae, James, Wang, Wenmin, Zadoorian, Armella, Hancock, Sarah E, Osborne, Brenna, Chen, Xiang, Wu, Jia-Wei, Turner, Nigel, Parton, Robert G, Li, Peng, Yang, Hongyuan
Format:	Journal Article
Language:	English
Published:	United States Rockefeller University Press 06-01-2020
Subjects:	1-Phosphatidylinositol 4-kinase Droplets Endoplasmic reticulum Endoplasmic Reticulum - metabolism HEK293 Cells Humans Integral membrane proteins Kinases Lipid Droplets - metabolism Lipid Metabolism Lipids Membranes Minor Histocompatibility Antigens - metabolism Monolayers Organelles Phosphatidylinositol Phosphates - metabolism Phosphatidylserine Phospholipid Transfer Proteins - metabolism Phospholipids Phosphotransferases (Alcohol Group Acceptor) - metabolism Receptors, Steroid - metabolism
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