Differential effect of the shape of calcium alginate matrices on the physiology of immobilized neuroblastoma N2a and Vero cells: A comparative study

In order to investigate the effect of cell immobilization in calcium alginate gels on cell physiology, we immobilized Vero or N2a neuroblastoma cells in gels shaped either as spherical beads or as thin membrane layers. Throughout a culture period of 4 weeks cell viability, RNA and cytoplasmic calciu...

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Bibliographic Details
Published in:	Biosensors & bioelectronics Vol. 23; no. 4; pp. 543 - 548
Main Authors:	Kintzios, S., Yiakoumetis, I., Moschopoulou, G., Mangana, O., Nomikou, K., Simonian, A.
Format:	Journal Article
Language:	English
Published:	Lausanne Elsevier B.V 30-11-2007 Elsevier Science
Subjects:	Alginates - chemistry Alginates - pharmacology Animals Biological and medical sciences Biotechnology Calcium alginate Cell Death - drug effects Cell immobilization Cell Line, Tumor Cell Proliferation - drug effects Cell Survival - drug effects Cells, Immobilized - drug effects Cercopithecus aethiops Fluorescence microscopy Fundamental and applied biological sciences. Psychology General aspects Glucuronic Acid - chemistry Glucuronic Acid - pharmacology Hexuronic Acids - chemistry Hexuronic Acids - pharmacology Immobilization techniques Methods. Procedures. Technologies Microscopy, Fluorescence Monkey African green kidney (Vero) cells N2a neuroblastoma cells Time Factors Vero Cells Monkey African green kidney (Vero) cells N2a neuroblastoma cells Calcium alginate Cell immobilization Fluorescence microscopy Calcium Monkey Immobilization Immobilized cell Alginates Neuroblastoma Kidney Vertebrata Mammalia Cell line Primates Physiology Comparative study
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