Conversations Between Insulin and Bone: Potential Mechanism Of High Bone Density in Patients with Berardinelli-Seip Congenital Lipodystrophy

Abstract Berardinelli-Seip Congenital Lipodystrophy (BSCL) is a rare autosomal recessive syndrome characterized by a difficulty storing lipid in adipocytes, low body fat, hypertriglyceridemia, and fat liver. The serum leptin is usually very low, and serum insulin, as well as HOMAIR (homeostasis mode...

Full description

Saved in:

Bibliographic Details
Published in:	Medical hypotheses Vol. 97; pp. 94 - 97
Main Authors:	Gomes Lima, Josivan, Nobrega Lima, Natalia, Helena C Nobrega, Lucia, Maria B Jeronimo, Selma
Format:	Journal Article
Language:	English
Published:	United States Elsevier Ltd 01-12-2016
Subjects:	Adipose Tissue Body Mass Index Bone and Bones - metabolism Bone Density Bone mass Density Homeostasis Humans Hyperinsulinism - metabolism Insulin Insulin - metabolism Insulin Resistance Internal Medicine Leptin Leptin - blood Leptin - metabolism Lipodystrophy Lipodystrophy, Congenital Generalized - diagnosis Lipodystrophy, Congenital Generalized - pathology Mutation Vitamin D - metabolism bone mass insulin density leptin lipodystrophy Lipodystrophy Bone mass Insulin Density Leptin
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!