8-Year Follow-up of Central Giant Cell Lesion Mimicking Apical Periodontitis

• Published in: Journal of endodontics Vol. 40; no. 10; pp. 1708 - 1712
• Main Authors: de Carvalhosa, Artur Aburad, DDS, MSc, PhD, Zandonade, Regina Maria Cristovan, DDS, de Souza Castro, Paulo Henrique, de Araújo Estrela, Cyntia Rodrigues, DDS, MSc, PhD, Borges, Álvaro Henrique, DDS, MSc, PhD, Estrela, Carlos, DDS, MSc, PhD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-10-2014
• Subjects: Adolescent; Apical periodontitis; central giant cell lesion; Dentistry; Diagnosis, Differential; differential diagnosis; Endocrinology & Metabolism; Female; Follow-Up Studies; Granuloma, Giant Cell - diagnosis; Humans; Mandibular Diseases - diagnosis; periapical lesion; Periapical Periodontitis - diagnosis; Radiography, Panoramic; differential diagnosis; Apical periodontitis; central giant cell lesion; periapical lesion
• ISSN: 0099-2399; 1878-3554
• DOI: 10.1016/j.joen.2014.06.010

Abstract Introduction Lesions of nonendodontic origin may mimic apical periodontitis. Central giant cell lesions (CGCLs) are aggressive or nonaggressive benign idiopathic intraosseous lesions of the jaw. This report describes a case of a CGCL in the periapical region of teeth #21–#26 of a 17-year-old female who sought orthodontic care because of a change in the position of tooth #23. Methods Clinical examination revealed mild facial asymmetry caused by increased volume in the mental region and cortical bone expansion but no cortical disruption. A panoramic radiograph showed a well-defined radiolucent osteolytic lesion involving teeth #21–#26. The cortical bone was not affected, and there was no root resorption. Incisional biopsy was performed, and the diagnosis was a CGCL. The lesion was enucleated surgically. CGCLs should be included in the differential diagnosis of jaw lesions that mimic apical periodontitis. Results The patient subsequently underwent orthodontic treatment successfully. Conclusions The 8-year clinical and radiographic follow-up confirmed lesion remission, no recurrence, and pulp vitality of all teeth.