Early loss of neostriatal striosome neurons in Huntington's disease

During the first years of symptomatic Huntington's disease (HD), no readily apparent pathology is seen in the neostriatum at autopsy. To investigate the pathological correlates of chorea and other early clinical signs, we examined the evolution of neuronal loss and accompanying astrocytosis in...

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Bibliographic Details

Published in:	Journal of neuropathology and experimental neurology Vol. 54; no. 1; p. 105
Main Authors:	Hedreen, J C, Folstein, S E
Format:	Journal Article
Language:	English
Published:	England 01-01-1995
Subjects:	Astrocytes - pathology Cadaver Cell Death Corpus Striatum - metabolism Corpus Striatum - pathology Glial Fibrillary Acidic Protein - metabolism Humans Huntington Disease - metabolism Huntington Disease - pathology Immunohistochemistry Neurons - pathology Time Factors
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