Effect of Text Messaging Plus Peer Navigation on Viral Suppression Among Youth With HIV in the iCARE Nigeria Pilot Study
Consistent with the global trend, youth with HIV (YWH) in Nigeria have high rates of viral nonsuppression. Hence, novel interventions are needed. Infectious Diseases Institute, College of Medicine, University of Ibadan, Nigeria. In a single-arm trial, participants aged 15-24 years received 48 weeks...
Saved in:
| Published in: | Journal of acquired immune deficiency syndromes (1999) Vol. 87; no. 4; pp. 1086 - 1092 |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
JAIDS Journal of Acquired Immune Deficiency Syndromes
01-08-2021
Lippincott Williams & Wilkins Ovid Technologies |
| Subjects: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | Consistent with the global trend, youth with HIV (YWH) in Nigeria have high rates of viral nonsuppression. Hence, novel interventions are needed.
Infectious Diseases Institute, College of Medicine, University of Ibadan, Nigeria.
In a single-arm trial, participants aged 15-24 years received 48 weeks of a combination intervention, comprising daily 2-way text message medication reminders plus peer navigation. The primary outcome measure was viral suppression less than 200 copies/mL. The secondary outcome measures included self-reported adherence on a visual analog scale and medication possession ratio, each dichotomized as ≥90% (good) or <90% (poor) adherence. The outcomes were analyzed using McNemar test. Retention in care, intervention feasibility and acceptability, and participants' satisfaction were also assessed.
Forty YWH (50% male participants) were enrolled: mean age 19.9 years (SD = 2.5), 55% perinatally infected, and 35% virologically suppressed at baseline. Compared with baseline, the odds of virologic suppression was higher at 24 weeks (odds ratio = 14.00, P < 0.001) and 48 weeks (odds ratio = 6.00, P = 0.013). Self-reported adherence (≥90%) increased from baseline at 24 weeks (63%, P = 0.008) and 48 weeks (68%, P = 0.031). Medication possession ratio ≥90% increased at weeks 24 and 48 (85% and 80%, respectively), achieving statistical significance at 24 weeks alone (P = 0.022). Retention in care at 48 weeks was 87.5%. All (37/37) participants at week 48 were fully or mostly satisfied with the intervention.
Daily 2-way text message reminders plus peer navigation is a promising combination intervention to improve viral suppression among YWH in Nigeria. |
|---|---|
| AbstractList | Background:Consistent with the global trend, youth with HIV (YWH) in Nigeria have high rates of viral nonsuppression. Hence, novel interventions are needed.Setting:Infectious Diseases Institute, College of Medicine, University of Ibadan, Nigeria.Methods:In a single-arm trial, participants aged 15–24 years received 48 weeks of a combination intervention, comprising daily 2-way text message medication reminders plus peer navigation. The primary outcome measure was viral suppression less than 200 copies/mL. The secondary outcome measures included self-reported adherence on a visual analog scale and medication possession ratio, each dichotomized as ≥90% (good) or <90% (poor) adherence. The outcomes were analyzed using McNemar test. Retention in care, intervention feasibility and acceptability, and participants' satisfaction were also assessed.Results:Forty YWH (50% male participants) were enrolled: mean age 19.9 years (SD = 2.5), 55% perinatally infected, and 35% virologically suppressed at baseline. Compared with baseline, the odds of virologic suppression was higher at 24 weeks (odds ratio = 14.00, P < 0.001) and 48 weeks (odds ratio = 6.00, P = 0.013). Self-reported adherence (≥90%) increased from baseline at 24 weeks (63%, P = 0.008) and 48 weeks (68%, P = 0.031). Medication possession ratio ≥90% increased at weeks 24 and 48 (85% and 80%, respectively), achieving statistical significance at 24 weeks alone (P = 0.022). Retention in care at 48 weeks was 87.5%. All (37/37) participants at week 48 were fully or mostly satisfied with the intervention.Conclusion:Daily 2-way text message reminders plus peer navigation is a promising combination intervention to improve viral suppression among YWH in Nigeria. BACKGROUNDConsistent with the global trend, youth with HIV (YWH) in Nigeria have high rates of viral nonsuppression. Hence, novel interventions are needed.SETTINGInfectious Diseases Institute, College of Medicine, University of Ibadan, Nigeria.METHODSIn a single-arm trial, participants aged 15-24 years received 48 weeks of a combination intervention, comprising daily 2-way text message medication reminders plus peer navigation. The primary outcome measure was viral suppression less than 200 copies/mL. The secondary outcome measures included self-reported adherence on a visual analog scale and medication possession ratio, each dichotomized as ≥90% (good) or <90% (poor) adherence. The outcomes were analyzed using McNemar test. Retention in care, intervention feasibility and acceptability, and participants' satisfaction were also assessed.RESULTSForty YWH (50% male participants) were enrolled: mean age 19.9 years (SD = 2.5), 55% perinatally infected, and 35% virologically suppressed at baseline. Compared with baseline, the odds of virologic suppression was higher at 24 weeks (odds ratio = 14.00, P < 0.001) and 48 weeks (odds ratio = 6.00, P = 0.013). Self-reported adherence (≥90%) increased from baseline at 24 weeks (63%, P = 0.008) and 48 weeks (68%, P = 0.031). Medication possession ratio ≥90% increased at weeks 24 and 48 (85% and 80%, respectively), achieving statistical significance at 24 weeks alone (P = 0.022). Retention in care at 48 weeks was 87.5%. All (37/37) participants at week 48 were fully or mostly satisfied with the intervention.CONCLUSIONDaily 2-way text message reminders plus peer navigation is a promising combination intervention to improve viral suppression among YWH in Nigeria. Consistent with the global trend, youth with HIV (YWH) in Nigeria have high rates of viral nonsuppression. Hence, novel interventions are needed. Infectious Diseases Institute, College of Medicine, University of Ibadan, Nigeria. In a single-arm trial, participants aged 15-24 years received 48 weeks of a combination intervention, comprising daily 2-way text message medication reminders plus peer navigation. The primary outcome measure was viral suppression less than 200 copies/mL. The secondary outcome measures included self-reported adherence on a visual analog scale and medication possession ratio, each dichotomized as ≥90% (good) or <90% (poor) adherence. The outcomes were analyzed using McNemar test. Retention in care, intervention feasibility and acceptability, and participants' satisfaction were also assessed. Forty YWH (50% male participants) were enrolled: mean age 19.9 years (SD = 2.5), 55% perinatally infected, and 35% virologically suppressed at baseline. Compared with baseline, the odds of virologic suppression was higher at 24 weeks (odds ratio = 14.00, P < 0.001) and 48 weeks (odds ratio = 6.00, P = 0.013). Self-reported adherence (≥90%) increased from baseline at 24 weeks (63%, P = 0.008) and 48 weeks (68%, P = 0.031). Medication possession ratio ≥90% increased at weeks 24 and 48 (85% and 80%, respectively), achieving statistical significance at 24 weeks alone (P = 0.022). Retention in care at 48 weeks was 87.5%. All (37/37) participants at week 48 were fully or mostly satisfied with the intervention. Daily 2-way text message reminders plus peer navigation is a promising combination intervention to improve viral suppression among YWH in Nigeria. |
| Author | Janulis, Patrick Kuhns, Lisa M. Adetunji, Adedotun Kapogiannis, Bill Adewumi, Olubusuyi M. Kuti, Kehinde M. Awolude, Olutosin Berzins, Baiba Johnson, Amy K. Okonkwor, Ogochukwu Oladeji, Bibilola D. Muldoon, Abigail Amoo, Paul Atunde, Hannah Taiwo, Babafemi O. Omigbodun, Olayinka Garofalo, Robert |
| AuthorAffiliation | Division of Infectious Diseases and Center for Global Health, Northwestern University, Chicago, IL Department of Family Medicine, University College Hospital, Ibadan, Nigeria Department of Medical Social Sciences, Northwestern University, Chicago, IL Division of Adolescent Medicine, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL Infectious Disease Institute, College of Medicine, University of Ibadan, Nigeria Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD Department of Virology, College of Medicine, University of Ibadan, Nigeria; and |
| AuthorAffiliation_xml | – name: Division of Adolescent Medicine, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL – name: Department of Medical Social Sciences, Northwestern University, Chicago, IL – name: Infectious Disease Institute, College of Medicine, University of Ibadan, Nigeria – name: Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD – name: Division of Infectious Diseases and Center for Global Health, Northwestern University, Chicago, IL – name: Department of Family Medicine, University College Hospital, Ibadan, Nigeria – name: Department of Virology, College of Medicine, University of Ibadan, Nigeria; and – name: 10 Department of Virology, College of Medicine, University of Ibadan, Nigeria – name: 2 Infectious Disease Institute, College of Medicine, University of Ibadan, Nigeria – name: 6 Department of Psychiatry, College of Medicine, University of Ibadan, Nigeria – name: 7 Department of Obstetrics and Gynecology, and Infectious Disease Institute, College of Medicine, University of Ibadan, Nigeria – name: 3 Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, USA – name: 1 Division of Infectious Diseases and Center for Global Health, Northwestern University, Chicago, USA – name: 11 Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA – name: 5 Department of Child and Adolescent Psychiatry, and Centre for Child and Adolescent Mental Health, College of Medicine, University of Ibadan, Nigeria – name: 4 Division of Adolescent Medicine, Ann and Robert H Lurie Children’s Hospital of Chicago, USA – name: 8 Department of Family Medicine, University College Hospital, Ibadan, Nigeria – name: 9 Department of Medical Social Sciences, Northwestern University, Chicago, USA |
| Author_xml | – sequence: 1 givenname: Babafemi O. surname: Taiwo fullname: Taiwo, Babafemi O. organization: Division of Infectious Diseases and Center for Global Health, Northwestern University, Chicago, IL – sequence: 2 givenname: Kehinde M. surname: Kuti fullname: Kuti, Kehinde M. organization: Infectious Disease Institute, College of Medicine, University of Ibadan, Nigeria – sequence: 3 givenname: Lisa M. surname: Kuhns fullname: Kuhns, Lisa M. organization: Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL – sequence: 4 givenname: Olayinka surname: Omigbodun fullname: Omigbodun, Olayinka organization: Department of Child and Adolescent Psychiatry, and Centre for Child and Adolescent Mental Health, College of Medicine, University of Ibadan, Nigeria – sequence: 5 givenname: Olutosin surname: Awolude fullname: Awolude, Olutosin organization: Infectious Disease Institute, College of Medicine, University of Ibadan, Nigeria – sequence: 6 givenname: Adedotun surname: Adetunji fullname: Adetunji, Adedotun organization: Department of Family Medicine, University College Hospital, Ibadan, Nigeria – sequence: 7 givenname: Baiba surname: Berzins fullname: Berzins, Baiba organization: Division of Infectious Diseases and Center for Global Health, Northwestern University, Chicago, IL – sequence: 8 givenname: Patrick surname: Janulis fullname: Janulis, Patrick organization: Department of Medical Social Sciences, Northwestern University, Chicago, IL – sequence: 9 givenname: Amy K. surname: Johnson fullname: Johnson, Amy K. organization: Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL – sequence: 10 givenname: Ogochukwu surname: Okonkwor fullname: Okonkwor, Ogochukwu organization: Division of Infectious Diseases and Center for Global Health, Northwestern University, Chicago, IL – sequence: 11 givenname: Bibilola D. surname: Oladeji fullname: Oladeji, Bibilola D. organization: Department of Medical Social Sciences, Northwestern University, Chicago, IL – sequence: 12 givenname: Abigail surname: Muldoon fullname: Muldoon, Abigail organization: Division of Adolescent Medicine, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL – sequence: 13 givenname: Olubusuyi M. surname: Adewumi fullname: Adewumi, Olubusuyi M. organization: Department of Virology, College of Medicine, University of Ibadan, Nigeria; and – sequence: 14 givenname: Paul surname: Amoo fullname: Amoo, Paul organization: Infectious Disease Institute, College of Medicine, University of Ibadan, Nigeria – sequence: 15 givenname: Hannah surname: Atunde fullname: Atunde, Hannah organization: Infectious Disease Institute, College of Medicine, University of Ibadan, Nigeria – sequence: 16 givenname: Bill surname: Kapogiannis fullname: Kapogiannis, Bill organization: Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD – sequence: 17 givenname: Robert surname: Garofalo fullname: Garofalo, Robert organization: Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34153015$$D View this record in MEDLINE/PubMed |
| BookMark | eNpdkdtu1DAQhiNURA_wBghZ4oabFE98SHyDtFotdKVSFlqKuLKcZJJ1ycaL7fTw9rhqKaWW5bE83_ya8b-f7YxuxCx7DfQQqCrff50tD-mjVUjFn2V7oDjPy6riO-kuCpFzYGI32w_hglKQnKsX2S7jIBgFsZddL7oOm0hcR87wOpLPGILp7diT1TAFskL05MRc2t5E60aS9rn1ZiCn03brE3v7ONu4xP90U1yTHzYdR8tzYkcS10jsfPZtQU5sj94asrKDi-Q0Tu3Ny-x5Z4aAr-7jQfb94-JsfpQff_m0nM-O84ZXQHMQooJOCQPYCoFNw2spjTRtI0sJJdbAKO-aqhGsMJ0qRN3VAlOK1aZqW8YOsg93utup3mDb4BhT_3rr7cb4G-2M1f9nRrvWvbvUFVdSqTIJvLsX8O73hCHqjQ0NDoMZ0U1BF4JzKAsJKqFvn6AXbvJjGk8XUioBDEAmit9RjXcheOwemgGqb63VyVr91NpU9ubxIA9Ff738p3vlhog-_BqmK_R6jWaI66QHhWSM5wUtgFY0_W1SBsr-AI7MsEw |
| CitedBy_id | crossref_primary_10_1371_journal_pone_0274031 crossref_primary_10_1186_s40814_023_01404_0 crossref_primary_10_1007_s11904_022_00611_3 crossref_primary_10_1186_s12981_023_00574_4 crossref_primary_10_3390_tropicalmed8110498 crossref_primary_10_1007_s10461_022_03959_0 crossref_primary_10_1089_apc_2022_0180 crossref_primary_10_1089_apc_2023_0094 crossref_primary_10_1007_s11904_023_00663_z |
| Cites_doi | 10.1097/QAI.0000000000001670 10.1089/apc.2018.0012 10.1186/s12889-019-6447-4 10.1080/09540121.2016.1226476 10.1037/0012-1649.43.6.1531 10.1056/NEJMoa1507198 10.1093/cid/ciq167 10.1371/journal.pone.0236801 10.1186/1472-6963-12-155 10.7448/IAS.18.1.20049 10.1097/QAD.0000000000001788 10.1097/QAD.0000000000000054 10.1007/s10461-012-0159-4 10.1007/s11904-019-00470-5 10.1089/apc.2018.0320 10.1080/09540121.2015.1110234 10.1002/jia2.25028 10.1007/s10461-015-1192-x 10.1097/QAD.0000000000000473 10.7448/IAS.20.4.21591 10.1016/S2352-3018(14)00003-4 10.1080/09540120802017636 10.1016/S0140-6736(12)60472-3 10.1371/journal.pone.0052856 10.1056/NEJMoa1506816 10.1016/j.puhe.2017.12.010 10.1056/NEJMoa1105243 10.1007/s10865-016-9770-6 10.1016/S0140-6736(16)00579-1 10.1016/S1473-3099(08)70265-2 10.1089/aid.2018.0242 10.1097/QAI.0000000000000863 10.1097/QAD.0000000000000252 10.1016/j.jclinepi.2004.04.002 |
| ContentType | Journal Article |
| Copyright | JAIDS Journal of Acquired Immune Deficiency Syndromes Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved. |
| Copyright_xml | – notice: JAIDS Journal of Acquired Immune Deficiency Syndromes – notice: Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved. |
| DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7T2 7T5 7TK 7U7 7U9 C1K H94 K9. 7X8 5PM |
| DOI | 10.1097/QAI.0000000000002694 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef Health and Safety Science Abstracts (Full archive) Immunology Abstracts Neurosciences Abstracts Toxicology Abstracts Virology and AIDS Abstracts Environmental Sciences and Pollution Management AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef Virology and AIDS Abstracts Toxicology Abstracts AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Health & Safety Science Abstracts Immunology Abstracts Neurosciences Abstracts Environmental Sciences and Pollution Management MEDLINE - Academic |
| DatabaseTitleList | Virology and AIDS Abstracts MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: ECM name: MEDLINE url: https://search.ebscohost.com/login.aspx?direct=true&db=cmedm&site=ehost-live sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1944-7884 |
| EndPage | 1092 |
| ExternalDocumentID | 10_1097_QAI_0000000000002694 34153015 00126334-202108010-00010 |
| Genre | Journal Article Research Support, N.I.H., Extramural |
| GeographicLocations | Nigeria |
| GeographicLocations_xml | – name: Nigeria |
| GrantInformation_xml | – fundername: NIAID NIH HHS grantid: P30 AI117943 – fundername: NICHD NIH HHS grantid: UH3 HD096920 – fundername: NICHD NIH HHS grantid: UG3 HD096920 – fundername: NCATS NIH HHS grantid: UL1 TR001422 – fundername: FIC NIH HHS grantid: D43 TW009608 |
| GroupedDBID | --- .-D .XZ .Z2 01R 0R~ 1J1 354 40H 4Q1 4Q2 4Q3 5GY 5RE 5VS 77Y 7O~ 8L- AAAAV AAAXR AAGIX AAHPQ AAIQE AAJCS AAMOA AAQKA AARTV AASCR AASOK AASXQ AAXQO ABASU ABBUW ABDIG ABIVO ABJNI ABVCZ ABXVJ ABZAD ACDDN ACEWG ACGFO ACGFS ACILI ACLDA ACOAL ACPRK ACWDW ACWRI ACXJB ACXNZ ADGGA ADHPY AE3 AE6 AEBDS AFDTB AFEXH AFRAH AFUWQ AGINI AHMBA AHOMT AHQNM AHVBC AIJEX AINUH AJIOK AJNWD AJZMW AKULP ALMA_UNASSIGNED_HOLDINGS ALMTX AMJPA AMKUR AMNEI AOHHW AWKKM BKOMP BOYCO BQLVK BYPQX C45 CS3 DIWNM E.X EBS EEVPB ERAAH EX3 F2K F2L F2M F2N F5P FCALG FL- FRJ FRP GNXGY GQDEL H0~ HLJTE HZ~ IKREB IKYAY IN~ IPNFZ JK3 JK8 K8S KD2 KMI L-C N~7 N~B O9- OAG OAH ODA ODMTH OHH OHYEH OLG OLH OLU OLV OLW OLY OLZ OPUJH OVD OVDNE OVIDH OVLEI OWV OWX OWY OWZ OXXIT P2P PQQKQ RIG RLZ RXW S4R S4S TAE TEORI TSPGW V2I VVN W2D W3M WOQ WOW X3V X3W XYM YOC CGR CUY CVF ECM EIF NPM AAYXX CITATION 7T2 7T5 7TK 7U7 7U9 C1K H94 K9. 7X8 5PM |
| ID | FETCH-LOGICAL-c4810-15581f95a1ed55ecc4b66a6adc67617eb1304fc8c532af925bfb5e7613ba8dd33 |
| ISSN | 1525-4135 |
| IngestDate | Tue Sep 17 21:12:04 EDT 2024 Sat Oct 26 05:48:27 EDT 2024 Thu Oct 10 15:57:27 EDT 2024 Thu Nov 21 21:11:32 EST 2024 Sat Nov 02 12:17:03 EDT 2024 Thu Nov 14 18:55:20 EST 2024 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 4 |
| Language | English |
| License | Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved. |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c4810-15581f95a1ed55ecc4b66a6adc67617eb1304fc8c532af925bfb5e7613ba8dd33 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496997 |
| PMID | 34153015 |
| PQID | 2669513116 |
| PQPubID | 31507 |
| PageCount | 7 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_8496997 proquest_miscellaneous_2544172619 proquest_journals_2669513116 crossref_primary_10_1097_QAI_0000000000002694 pubmed_primary_34153015 wolterskluwer_health_00126334-202108010-00010 |
| PublicationCentury | 2000 |
| PublicationDate | 2021-August-1 2021-08-01 2021-08-1 20210801 |
| PublicationDateYYYYMMDD | 2021-08-01 |
| PublicationDate_xml | – month: 08 year: 2021 text: 2021-August-1 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: Hagerstown |
| PublicationSubtitle | JAIDS |
| PublicationTitle | Journal of acquired immune deficiency syndromes (1999) |
| PublicationTitleAlternate | J Acquir Immune Defic Syndr |
| PublicationYear | 2021 |
| Publisher | JAIDS Journal of Acquired Immune Deficiency Syndromes Lippincott Williams & Wilkins Ovid Technologies |
| Publisher_xml | – name: JAIDS Journal of Acquired Immune Deficiency Syndromes – name: Lippincott Williams & Wilkins Ovid Technologies |
| References | Patton (R18-20230927) 2016; 387 Bygrave (R42-20230927) 2012; 7 Mills (R26-20230927) 2014; 1 Meloni (R47-20230927) 2020; 15 Ammon (R20-20230927) 2018; 157 MacKenzie (R51-20230927) 2017; 20 Vollmer (R35-20230927) 2012; 12 Tabb (R48-20230927) 2018; 32 DeSilva (R6-20230927) 2009; 21 Resnick (R15-20230927) 2012; 379 Mark (R7-20230927) 2017; 20 Kahana (R36-20230927) 2013; 17 Danel (R4-20230927) 2015; 373 Adetunji (R11-20230927) 2017; 29 Cohen (R3-20230927) 2011; 365 McMahon (R33-20230927) 2011; 52 Boender (R39-20230927) 2015; 61 Ojwang (R24-20230927) 2016; 28 Lester (R10-20230927) 2008; 8 Steinberg (R16-20230927) 2007; 43 Casale (R23-20230927) 2019; 33 Ahonkhai (R46-20230927) 2018; 78 Grieb (R50-20230927) 2018; 32 Finitsis (R30-20230927) 2016; 39 Mark (R21-20230927) 2019; 16 Adejumo (R17-20230927) 2015; 18 Garofalo (R14-20230927) 2016; 20 Fairman (R31-20230927) 2000; 6 Nwogu (R49-20230927) 2019; 35 Lundgren (R2-20230927) 2015; 373 Chaiyachati (R27-20230927) 2014; 28 Grossberg (R32-20230927) 2004; 57 Koech (R41-20230927) 2014; 28 Grimsrud (R25-20230927) 2016; 71 Lamb (R43-20230927) 2014; 28 Auld (R8-20230927) 2014; 63 Willis (R40-20230927) 2019; 19 |
| References_xml | – volume: 78 start-page: 322 year: 2018 ident: R46-20230927 article-title: High medication possession ratios associated with greater risk of virologic failure among youth compared with adults in a Nigerian cohort publication-title: J Acquir Immune Defic Syndr. doi: 10.1097/QAI.0000000000001670 contributor: fullname: Ahonkhai – volume: 32 start-page: 208 year: 2018 ident: R50-20230927 article-title: The clinic environment as a form of social support for adolescents and young adults living with HIV publication-title: AIDS Patient Care STDs. doi: 10.1089/apc.2018.0012 contributor: fullname: Grieb – volume: 19 start-page: 117 year: 2019 ident: R40-20230927 article-title: Effectiveness of community adolescent treatment supporters (CATS) interventions in improving linkage and retention to care, adherence to ART and psychosocial well-being: a randomized trial among adolescents living with HIV in Zimbabwe publication-title: BMC Public Health. doi: 10.1186/s12889-019-6447-4 contributor: fullname: Willis – volume: 29 start-page: 575 year: 2017 ident: R11-20230927 article-title: Mobile phone use for a social strategy to improve antiretroviral refill experience at a low-resource HIV clinic: patient responses from Nigeria publication-title: AIDS Care. doi: 10.1080/09540121.2016.1226476 contributor: fullname: Adetunji – volume: 43 start-page: 1531 year: 2007 ident: R16-20230927 article-title: Age differences in resistance to peer influence publication-title: Dev Psychol. doi: 10.1037/0012-1649.43.6.1531 contributor: fullname: Steinberg – volume: 373 start-page: 808 year: 2015 ident: R4-20230927 article-title: A trial of early antiretrovirals and isoniazid preventive therapy in Africa publication-title: N Engl J Med. doi: 10.1056/NEJMoa1507198 contributor: fullname: Danel – volume: 52 start-page: 493 year: 2011 ident: R33-20230927 article-title: Pharmacy adherence measures to assess adherence to antiretroviral therapy: review of the literature and implications for treatment monitoring publication-title: Clin Infect Dis. doi: 10.1093/cid/ciq167 contributor: fullname: McMahon – volume: 15 start-page: e0236801 year: 2020 ident: R47-20230927 article-title: Longitudinal evaluation of adherence, retention, and transition patterns of adolescents living with HIV in Nigeria publication-title: PLoS One. doi: 10.1371/journal.pone.0236801 contributor: fullname: Meloni – volume: 12 start-page: 155 year: 2012 ident: R35-20230927 article-title: Comparison of pharmacy-based measures of medication adherence publication-title: BMC Health Serv Res. doi: 10.1186/1472-6963-12-155 contributor: fullname: Vollmer – volume: 18 start-page: 20049 year: 2015 ident: R17-20230927 article-title: Contemporary issues on the epidemiology and antiretroviral adherence of HIV-infected adolescents in sub-Saharan Africa: a narrative review publication-title: J Int AIDS Soc. doi: 10.7448/IAS.18.1.20049 contributor: fullname: Adejumo – volume: 61 start-page: 1749 year: 2015 ident: R39-20230927 article-title: Pretreatment HIV drug resistance increases regimen switches in sub-Saharan Africa publication-title: Clin Infect Dis. contributor: fullname: Boender – volume: 32 start-page: 1115 year: 2018 ident: R48-20230927 article-title: Antiretroviral drug concentrations in hair are associated with virologic outcomes among young people living with HIV in Tanzania publication-title: AIDS. doi: 10.1097/QAD.0000000000001788 contributor: fullname: Tabb – volume: 28 start-page: 559 year: 2014 ident: R43-20230927 article-title: High attrition before and after ART initiation among youth (15-24 years of age) enrolled in HIV care publication-title: AIDS. doi: 10.1097/QAD.0000000000000054 contributor: fullname: Lamb – volume: 6 start-page: 499 year: 2000 ident: R31-20230927 article-title: Evaluating medication adherence: which measure is right for your program? publication-title: J Manag Care Pharm. contributor: fullname: Fairman – volume: 17 start-page: 41 year: 2013 ident: R36-20230927 article-title: A meta-analysis of adherence to antiretroviral therapy and virologic responses in HIV-infected children, adolescents, and young adults publication-title: AIDS Behav. doi: 10.1007/s10461-012-0159-4 contributor: fullname: Kahana – volume: 16 start-page: 467 year: 2019 ident: R21-20230927 article-title: Peer support for adolescents and young people living with HIV in sub-saharan africa: emerging insights and a methodological agenda publication-title: Curr HIV/AIDS Rep. doi: 10.1007/s11904-019-00470-5 contributor: fullname: Mark – volume: 33 start-page: 237 year: 2019 ident: R23-20230927 article-title: Recent interventions to improve retention in HIV care and adherence to antiretroviral treatment among adolescents and youth: a systematic review publication-title: AIDS Patient Care STDS doi: 10.1089/apc.2018.0320 contributor: fullname: Casale – volume: 28 start-page: 500 year: 2016 ident: R24-20230927 article-title: Loss to follow-up among youth accessing outpatient HIV care and treatment services in Kisumu, Kenya publication-title: AIDS Care. doi: 10.1080/09540121.2015.1110234 contributor: fullname: Ojwang – volume: 20 start-page: e25028 year: 2017 ident: R51-20230927 article-title: Greater retention in care among adolescents on antiretroviral treatment accessing “Teen Club” an adolescent-centred differentiated care model compared with standard of care: a nested case control study at a tertiary referral hospital in Malawi publication-title: J Int AIDS Soc. doi: 10.1002/jia2.25028 contributor: fullname: MacKenzie – volume: 20 start-page: 1049 year: 2016 ident: R14-20230927 article-title: A randomized controlled trial of personalized text message reminders to promote medication adherence among HIV-positive adolescents and young adults publication-title: AIDS Behav. doi: 10.1007/s10461-015-1192-x contributor: fullname: Garofalo – volume: 28 start-page: 2729 year: 2014 ident: R41-20230927 article-title: Characteristics and outcomes of HIV-infected youth and young adolescents enrolled in HIV care in Kenya publication-title: AIDS. doi: 10.1097/QAD.0000000000000473 contributor: fullname: Koech – volume: 20 start-page: 21591 issue: Suppl 3 year: 2017 ident: R7-20230927 article-title: HIV treatment and care services for adolescents: a situational analysis of 218 facilities in 23 sub-Saharan African countries publication-title: J Int AIDS Soc. doi: 10.7448/IAS.20.4.21591 contributor: fullname: Mark – volume: 1 start-page: e104 year: 2014 ident: R26-20230927 article-title: Interventions to promote adherence to antiretroviral therapy in Africa: a network meta-analysis publication-title: Lancet HIV. doi: 10.1016/S2352-3018(14)00003-4 contributor: fullname: Mills – volume: 21 start-page: 70 year: 2009 ident: R6-20230927 article-title: Youth, unemployment, and male gender predict mortality in AIDS patients started on HAART in Nigeria publication-title: AIDS Care. doi: 10.1080/09540120802017636 contributor: fullname: DeSilva – volume: 379 start-page: 1564 year: 2012 ident: R15-20230927 article-title: Seizing the opportunities of adolescent health publication-title: Lancet. doi: 10.1016/S0140-6736(12)60472-3 contributor: fullname: Resnick – volume: 7 start-page: e52856 year: 2012 ident: R42-20230927 article-title: Antiretroviral therapy outcomes among adolescents and youth in rural Zimbabwe publication-title: PLoS One. doi: 10.1371/journal.pone.0052856 contributor: fullname: Bygrave – volume: 373 start-page: 795 year: 2015 ident: R2-20230927 article-title: Initiation of antiretroviral therapy in early asymptomatic HIV infection publication-title: N Engl J Med. doi: 10.1056/NEJMoa1506816 contributor: fullname: Lundgren – volume: 157 start-page: 20 year: 2018 ident: R20-20230927 article-title: Factors impacting antiretroviral therapy adherence among human immunodeficiency virus-positive adolescents in sub-Saharan Africa: a systematic review publication-title: Public Health doi: 10.1016/j.puhe.2017.12.010 contributor: fullname: Ammon – volume: 365 start-page: 493 year: 2011 ident: R3-20230927 article-title: Prevention of HIV-1 infection with early antiretroviral therapy publication-title: N Engl J Med. doi: 10.1056/NEJMoa1105243 contributor: fullname: Cohen – volume: 39 start-page: 1043 year: 2016 ident: R30-20230927 article-title: Visual analogue scale (VAS) measurement of antiretroviral adherence in people living with HIV (PLWH): a meta-analysis publication-title: J Behav Med. doi: 10.1007/s10865-016-9770-6 contributor: fullname: Finitsis – volume: 387 start-page: 2423 year: 2016 ident: R18-20230927 article-title: Our future: a Lancet commission on adolescent health and wellbeing publication-title: Lancet. doi: 10.1016/S0140-6736(16)00579-1 contributor: fullname: Patton – volume: 8 start-page: 738 year: 2008 ident: R10-20230927 article-title: Mobile phones: exceptional tools for HIV/AIDS, health, and crisis management publication-title: Lancet Infect Dis. doi: 10.1016/S1473-3099(08)70265-2 contributor: fullname: Lester – volume: 35 start-page: 642 year: 2019 ident: R49-20230927 article-title: Willingness to donate hair samples for research among people living with HIV/AIDS attending a tertiary health facility in Ibadan, Nigeria publication-title: AIDS Res Hum Retroviruses. doi: 10.1089/aid.2018.0242 contributor: fullname: Nwogu – volume: 71 start-page: e16 year: 2016 ident: R25-20230927 article-title: Implementation and operational research: community-based adherence clubs for the management of stable Antiretroviral therapy patients in cape town, South Africa: a cohort study publication-title: J Acquir Immune Defic Syndr. doi: 10.1097/QAI.0000000000000863 contributor: fullname: Grimsrud – volume: 28 start-page: S187 issue: Suppl 2 year: 2014 ident: R27-20230927 article-title: Interventions to improve adherence to antiretroviral therapy: a rapid systematic review publication-title: AIDS. doi: 10.1097/QAD.0000000000000252 contributor: fullname: Chaiyachati – volume: 63 start-page: 1097 year: 2014 ident: R8-20230927 article-title: Antiretroviral therapy enrollment characteristics and outcomes among HIV-infected adolescents and young adults compared with older adults--seven African countries, 2004-2013 publication-title: MMWR Morb Mortal Wkly Rep. contributor: fullname: Auld – volume: 57 start-page: 1107 year: 2004 ident: R32-20230927 article-title: A time-to-prescription-refill measure of antiretroviral adherence predicted changes in viral load in HIV publication-title: J Clin Epidemiol. doi: 10.1016/j.jclinepi.2004.04.002 contributor: fullname: Grossberg |
| SSID | ssj0016449 |
| Score | 2.4717774 |
| Snippet | Consistent with the global trend, youth with HIV (YWH) in Nigeria have high rates of viral nonsuppression. Hence, novel interventions are needed.
Infectious... Background:Consistent with the global trend, youth with HIV (YWH) in Nigeria have high rates of viral nonsuppression. Hence, novel interventions are... BACKGROUNDConsistent with the global trend, youth with HIV (YWH) in Nigeria have high rates of viral nonsuppression. Hence, novel interventions are... |
| SourceID | pubmedcentral proquest crossref pubmed wolterskluwer |
| SourceType | Open Access Repository Aggregation Database Index Database Publisher |
| StartPage | 1086 |
| SubjectTerms | Adolescent Anti-HIV Agents - administration & dosage Anti-HIV Agents - therapeutic use Cohort Studies Female HIV HIV Infections - drug therapy HIV-1 Human immunodeficiency virus Humans Infectious diseases Intervention Male Medication Adherence Nigeria - epidemiology Patient Satisfaction Peer Influence Pilot Projects Retention Short message service Text Messaging Young Adult |
| Title | Effect of Text Messaging Plus Peer Navigation on Viral Suppression Among Youth With HIV in the iCARE Nigeria Pilot Study |
| URI | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&NEWS=n&CSC=Y&PAGE=fulltext&D=ovft&AN=00126334-202108010-00010 https://www.ncbi.nlm.nih.gov/pubmed/34153015 https://www.proquest.com/docview/2669513116 https://search.proquest.com/docview/2544172619 https://pubmed.ncbi.nlm.nih.gov/PMC8496997 |
| Volume | 87 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1bb9MwFLbWTUJICHEdhYGMxFtU0dyTx7K1KqJbC2RoPEVO4qwWXTLRZYN_zzm2cymdEDxQVVHrRI3c8-X42P7Odwh5k6Wp7WBGD_NTmKB4KfjBxA0GKG2Xh6kPQSkuDUw_-ydnwdHYGe_06oqhbdt_tTS0ga0xc_YfrN38KDTAZ7A5HMHqcPwru2s5YogBI_C7xjGWOJGFiBaram0sOCb5smsprIGhYmF8EZijj9U9FSW2MEayANFXLK4HXgMOU5gjaj6kOBx9GgN-zrEvxkKsyivJRdzYHe5EuSxFqjFEtQITUTBJCyUrZL5nLZagxKIghOysSkRM3JRqPyRhOb8QxrzddNIMBL5Eqcd2OfdDtVSTgplYs7Z5fiHOkzKrCmO-Yj9h6s26Kx2W2fDs9ErHLYoVcqVDrCSdaH4tsnZDoqZgarduuQMYrtX-OVdtoeMgl9LpjgV68BfdhY5LVZu3VuzWX1UFv60BSAkbfxy9V8KY-oXpwu2AW5MMTubx5HQ2i6PxWdQjexa4SvDUe6PJUfSu2QmDeDWUmr-6B3X6Z-i_ve0um-HV1pxpm_p776ZEWsb6m8zK6MRW0QNyX8OFjhSaH5IdXjwid4417eMx-aFATcucIqhpA2qKoKYIatqCmsJbgpp2QE0lqKkENUVQUwA1FQUFUFMJaqpBTSWoqQT1E3I6GUeH04EuGTJInQB5Rq4bmHnoMpNnrgvuyUk8j3ksSz0fYnUITOyhk6dB6toWy0PLTfLE5XDKTliQZbb9lOwWZcGfEZpwaINw3eN54IR5wJDy4Odhnng-T4dOnwzqfzq-VMowcc3oAMvEv1umTw5qc8TaX6xjCI9himObptcnr5vT4OFx244VvKzgGlkmEFc6-mRfWa-5IcSgLgzRbp_4G3ZtLkD1-M0zhVhKFXnolBeGPnRjAwGxyr9Grqvl2bYzwCcRppWmFKAwh8__3I0X5G776B6Q3avvFX9JeuuseqWR_QsrM-uC |
| link.rule.ids | 230,315,782,786,887,27933,27934,64549,64569,65344,65364 |
| linkProvider | Ovid |
| linkToHtml | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwvV1db5RAFJ3oNlET47cVrTomhje0LMwADzwQSl10l6zu2tonAsNMJTbQlN2q_957-di4Nj744oYshJkAE-7MnOGeey4hrwshLBsjejJHwAKFCxgHc-YaKG2nPOEAKMVPA5OFk3xxDyKUyRm4qhh81py_wV07TOMBpsPBdeHSf7_Qk-h44Vd6uAj9E30evIvaz9RIktAP_PpSrfQg8XEO55ZlgwmMkUNntsHTGIi1wxk82ojsBGE8jTfuBgAFXiusOmYGjOpsiLHznLcfg7jTOOx_GPm5PYddAaZX-ZW3v9fo-26-tdT33yaww7v_qen3yJ0e4dKgM8n75JqsHpAbs96H_5D86ASTaa3oEq5KZ5iEBVMl0fnZuqFzKS9okl220h91RWE7KqF5FPOPdqTdigaYIomeYPo_elzC3yQ-omVFAc3SMgw-RTQpT7Fv0Xl5Vq8osiV_PiKfD6NlODH6_A-GsF0kjTDmmspjmSkLxsDW7JzzjGeF4A4AL5hlrH1bCVcwa5wpb8xylTMJRVaeuUVhWY_JqKor-YTQXMI5wF5cKtf2lJuh_9pRnsq5I8W-rRFjeKPpeSfzkQ7uebCA9E8L0Mje8NrTvtM3KWAdwKuWaXKNvNoUQ3dFH0xWyXoNddqcb7hs1chuZyWbGwKgYDDeMo04W_azqYBS4NslVfm1lQSHRnHPc6AZW5aWdsG06d-s4uk_1n9Jbk6Ws2k6jZMPz8gtLO3IkHtktLpYy-fkelOsX_Td6xfJLytE |
| linkToPdf | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwvV1Lb9NAEF5BK1VIiPfDUGCRkG-GOvau7YMPluOQQGsZEvo4WfZ6t7Wo7KpOCv33zPgRESoOXIisxMquHG387ey3nplvCHlXCGHZmNGTOQI2KFyAHcyZa6C0nfKEA6QUHw1M50587I4jlMkZPPiYfNZcvMeP1kzjCZbDwX3hwv8018N56J_ocXQ092M9CT5G7WNqDJLQk_HEv9bHfn2llnoQ-7iSc8uyAQgjjKQz2xRqTMfaRhkrmALbQTjbn62dDkANvFZedcQMsO1syLTznA9fglmndNi_MP9zcyW7QU9vRlne_VGjB7z53gbA_7aMTe7_1z_gAbnXs10adPB8SG7J6hHZOej9-Y_Jz048mdaKLuDa9AALsmDZJJqcrxqaSHlJ4-yqlQGpKwrHYQmDpFiLtAvgrWiA5ZLoCZYCpEclvE1nh7SsKDBbWobB14jG5SnOM5qU5_WSYuTk9RPybRItwqnR14IwhO1iAAljrqk8lpmyYAxwZ-ecZzwrBHeAhMGKY-3ZSriCWaNMeSOWq5xJaLLyzC0Ky3pKtqq6ks8JzSV8BzyMS-XannIz9GU7ylM5d6TYszViDPc1vegkP9LBVQ84SP_EgUZ2h5uf9gagSYH3AHe1TJNr5O26GaYu-mOyStYr6NPWf8MtrEaedVhZ_yCQCwa2l2nE2UDRugPKgm-2VOVZKw8Og-Ke58AwNvCWdom16d9Q8eIf-78hOwC4dH8Wf35J7mBjFxe5S7aWlyv5itxuitXrfo79AtM3LiY |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Effect+of+Text+Messaging+Plus+Peer+Navigation+on+Viral+Suppression+Among+Youth+With+HIV+in+the+iCARE+Nigeria+Pilot+Study&rft.jtitle=Journal+of+acquired+immune+deficiency+syndromes+%281999%29&rft.au=Taiwo%2C+Babafemi+O&rft.au=Kuti%2C+Kehinde+M&rft.au=Kuhns%2C+Lisa+M&rft.au=Omigbodun+Olayinka&rft.date=2021-08-01&rft.pub=Lippincott+Williams+%26+Wilkins+Ovid+Technologies&rft.issn=1525-4135&rft.eissn=1944-7884&rft.volume=87&rft.issue=4&rft.spage=1086&rft.epage=1092&rft_id=info:doi/10.1097%2FQAI.0000000000002694&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1525-4135&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1525-4135&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1525-4135&client=summon |