Grape pomace as a source of phenolic compounds and diverse bioactive properties

• Published in: Food chemistry Vol. 253; pp. 132 - 138
• Main Authors: Peixoto, Carla M., Dias, Maria Inês, Alves, Maria José, Calhelha, Ricardo C., Barros, Lillian, Pinho, Simão P., Ferreira, Isabel C.F.R.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01-07-2018
• Subjects: Anthocyanins - analysis; Anthocyanins - isolation & purification; Anthocyanins - pharmacology; Anti-Bacterial Agents - analysis; Anti-Bacterial Agents - isolation & purification; Anti-Bacterial Agents - pharmacology; Antioxidants - analysis; Antioxidants - isolation & purification; Antioxidants - pharmacology; Bio-residues; Bioactivities; Food Handling; Fruit - chemistry; Grape pomace; Phenolic compounds; Phenols - analysis; Phenols - isolation & purification; Phenols - pharmacology; Propionates - analysis; Propionates - isolation & purification; Propionates - pharmacology; Seeds - chemistry; Vitis - chemistry; Vitis vinifera L; Wine; Vitis vinifera L; Bio-residues; Phenolic compounds; Bioactivities; Grape pomace
• ISSN: 0308-8146; 1873-7072
• DOI: 10.1016/j.foodchem.2018.01.163

•The bio-residues from the wine industry were explored for their bioactivities.•The seeds showed the highest amount of phenolic compounds.•The skins presented the highest levels of anthocyanins.•Highest antioxidant, cytotoxic and antibacterial potential was observed by seeds.•Strong correlations were observed between polyphenols and bioactivities.
The bio-residues resulting from the wine industry (grape pomace made up of skins, seeds and stems) are often undervalued but constitute a potential source of bioactive phenolic compounds that can be applied in several industries. In this context, the aim of the present study was to evaluate the phenolic profile of Vitis vinifera L. grape pomace (skins, seeds and their mixture), and correlate them with its antioxidant, cytotoxic and antibacterial activities. The seeds showed the highest amount of phenolic compounds and also the highest antioxidant, cytotoxic and antibacterial activities. The skins revealed the highest levels of anthocyanins and p-coumaric acid hexoside. Strong correlations were observed between the presence of phenolic compounds and all the bioactivities studied. These by-products are good sources of phenolic compounds with high antioxidant and antibacterial activity, and also presenting a moderate cytotoxicity activity. These added-value by-products have great applicability in food, pharmaceutical and cosmetic industries.