Dexmedetomidine for deep brain stimulator placement in a child with primary generalized dystonia: case report and literature review

• Published in: Journal of clinical anesthesia Vol. 21; no. 3; pp. 213 - 216
• Main Authors: Maurtua, Marco A., MD, Cata, Juan P., MD, Martirena, Margarita, MD, Deogaonkar, Millind, MD, Rezai, Ali, MD, Sung, Wai, MD, Lotto, Michelle, MD, Niezgoda, Julie, MD, Schubert, Armin, MD, MBA
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01-05-2009; Elsevier; Elsevier Limited
• Subjects: Airway management; Analgesics; Anesthesia; Anesthesia & Perioperative Care; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Child; Children & youth; Deep brain stimulation; Deep Brain Stimulation - methods; Dexmedetomidine; Dexmedetomidine - therapeutic use; Dystonia; Dystonic Disorders - therapy; Electrodes; Humans; Hypnotics and Sedatives - therapeutic use; Intubation; Male; Medical imaging; Medical practices; Medical sciences; Pain Medicine; Pediatric sedation; Pediatrics; Surgery; Ventilation; Pediatrics; Dystonia; Pediatric sedation; Deep brain stimulation; Dexmedetomidine; Human; α2-Adrenergic receptor; Agonist; Nervous system diseases; Sedation; Involuntary movement; Cerebral disorder; Encephalon; Case study; Striated muscle disease; Central nervous system disease; Anesthesia; α-Adrenergic receptor agonist; Neurological disorder; Child; Extrapyramidal syndrome
• ISSN: 0952-8180; 1873-4529
• DOI: 10.1016/j.jclinane.2008.06.038

Abstract Dexmedetomidine, which is a relatively selective alpha2-adrenoceptor agonist, is used for sedation and analgesia in intensive care unit patients, during awake craniotomies in pediatric and adult patients, and during magnetic resonance imaging, with minimal depression of respiratory function. The successful use of dexmedetomidine in a pediatric patient undergoing bilateral deep brain stimulator placement for the treatment of generalized dystonia, is presented.