Transcriptomic responses of European flounder ( Platichthys flesus) to model toxicants

The temporal transcriptomic responses in liver of Platichthys flesus to model environmental pollutants were studied over a 16-day time span after intraperitoneal injection with cadmium chloride (50 μg/kg in saline), 3-methylcholanthrene (25 mg/kg in olive oil), Aroclor 1254 (50 mg/kg in olive oil),...

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Bibliographic Details
Published in:	Aquatic toxicology Vol. 90; no. 2; pp. 83 - 91
Main Authors:	Williams, Tim D., Diab, Amer, Ortega, Fernando, Sabine, Victoria S., Godfrey, Rita E., Falciani, Francesco, Chipman, J. Kevin, George, Stephen G.
Format:	Journal Article
Language:	English
Published:	Amsterdam Elsevier B.V 11-11-2008 Amsterdam; New York: Elsevier Science Elsevier
Subjects:	acute toxicity Agnatha. Pisces Animal, plant and microbial ecology Animals apoptosis Applied ecology Biological and medical sciences cadmium chlorinated hydrocarbons Ecotoxicogenomics Ecotoxicology, biological effects of pollution Fish Flounder Flounder - physiology Fundamental and applied biological sciences. Psychology Gene Expression Profiling Gene Expression Regulation - drug effects General aspects Genes - genetics genomics genotoxicity Lindane liver Liver - drug effects Marine mechanism of action Microarray microarray technology Oligonucleotide Array Sequence Analysis Oxidative stress PCB Peroxisome proliferators peroxisomes physiological response Platichthys flesus Polycyclic aromatic hydrocarbon polycyclic aromatic hydrocarbons Principal Component Analysis protein synthesis Time Factors transcriptomics Vertebrates: general zoology, morphology, phylogeny, systematics, cytogenetics, geographical distribution Water Pollutants, Chemical - toxicity Europe AN, Atlantic Cd Oxidative stress MIAME Peroxisome proliferators Polycyclic aromatic hydrocarbon Lindane Ecotoxicogenomics Microarray Flounder PCB GENIPOL Fish OSPAR SAM Insecticide Toxicity Platichthys flesus Freshwater environment Marine environment Persistent organic pollutant Aquatic environment Organochlorine compounds Chlorine Organic compounds Pisces Organic compounds Cadmium Ecotoxicology Hydrocarbon Pesticides Polychlorobiphenyls Polycyclic aromatic compound Heavy metal Vertebrata Peroxisome Poison Models
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