Effect of Cavity Disinfectants on Dentin Bond Strength and Clinical Success of Composite Restorations-A Systematic Review of In Vitro, In Situ and Clinical Studies

Cavity disinfection becomes an important step before a dental restorative procedure. The disinfection can be obtained cleaning the dental cavity with antimicrobial agents before the use of adhesive systems. The aim of this study was to conduct a systematic review on the effect of different cavity di...

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Published in:International journal of molecular sciences Vol. 22; no. 1; p. 353
Main Authors: Coelho, Ana, Amaro, Inês, Rascão, Beatriz, Marcelino, Inês, Paula, Anabela, Saraiva, José, Spagnuolo, Gianrico, Marques Ferreira, Manuel, Miguel Marto, Carlos, Carrilho, Eunice
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Abstract Cavity disinfection becomes an important step before a dental restorative procedure. The disinfection can be obtained cleaning the dental cavity with antimicrobial agents before the use of adhesive systems. The aim of this study was to conduct a systematic review on the effect of different cavity disinfectants on restorations' adhesion and clinical success. A search was carried out through the Cochrane Library, PubMed, and Web of Science. In vitro and in situ studies reporting results on dentin bond strength tests, and clinical studies published until August 2020, in English, Spanish and Portuguese were included. The methodological quality assessment of the clinical studies was carried out using the Revised Cochrane risk-of-bias tool. Chlorhexidine could preserve adhesion to dentin. EDTA and ethanol had positive results that should be further confirmed. Given the significant lack of scientific evidence, the use of lasers, fluoridated agents, sodium hypochlorite, or other products as cavity disinfectants should be avoided. Chlorhexidine is a safe option for cavity disinfection with adequate preservation of adhesion to dentin. Moreover, future researches should be focused on the efficacy of these disinfectants against cariogenic bacteria and their best application methods.
AbstractList Cavity disinfection becomes an important step before a dental restorative procedure. The disinfection can be obtained cleaning the dental cavity with antimicrobial agents before the use of adhesive systems. The aim of this study was to conduct a systematic review on the effect of different cavity disinfectants on restorations’ adhesion and clinical success. A search was carried out through the Cochrane Library, PubMed, and Web of Science. In vitro and in situ studies reporting results on dentin bond strength tests, and clinical studies published until August 2020, in English, Spanish and Portuguese were included. The methodological quality assessment of the clinical studies was carried out using the Revised Cochrane risk-of-bias tool. Chlorhexidine could preserve adhesion to dentin. EDTA and ethanol had positive results that should be further confirmed. Given the significant lack of scientific evidence, the use of lasers, fluoridated agents, sodium hypochlorite, or other products as cavity disinfectants should be avoided. Chlorhexidine is a safe option for cavity disinfection with adequate preservation of adhesion to dentin. Moreover, future researches should be focused on the efficacy of these disinfectants against cariogenic bacteria and their best application methods.
Author Miguel Marto, Carlos
Marques Ferreira, Manuel
Rascão, Beatriz
Paula, Anabela
Spagnuolo, Gianrico
Coelho, Ana
Marcelino, Inês
Saraiva, José
Carrilho, Eunice
Amaro, Inês
AuthorAffiliation 4 Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”, 80131 Napoli, Italy; gspagnuo@unina.it
6 Institute of Endodontics, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal
5 Institute of Dentistry, I. M. Sechenov First Moscow State Medical University, 119435 Moscow, Russia
2 Area of Environment Genetics and Oncobiology (CIMAGO), Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal; m.mferreira@netcabo.pt
8 Institute of Experimental Pathology, Faculty of Medicine, University of Coimbra, 3004-548 Coimbra, Portugal
1 Institute of Integrated Clinical Practice, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal; ines.amaros@hotmail.com (I.A.); beatriznmfrascao@gmail.com (B.R.); inescarvalhomarcelino@gmail.com (I.M.); anabelabppaula@sapo.pt (A.P.); ze-93@hotmail.com (J.S.); cmiguel.marto@uc.pt (C.M.M.); eunicecarrilho
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/33396354$$D View this record in MEDLINE/PubMed
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Keywords dental caries
cavity disinfection
adhesion
chlorhexidine
antimicrobial substances
bonding
Language English
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SecondaryResourceType review_article
Snippet Cavity disinfection becomes an important step before a dental restorative procedure. The disinfection can be obtained cleaning the dental cavity with...
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StartPage 353
SubjectTerms Adhesion
Adhesives
Anti-Infective Agents, Local - pharmacology
Antiinfectives and antibacterials
Antimicrobial agents
antimicrobial substances
Antiseptics
Bond strength
bonding
cavity disinfection
Chlorhexidine
Composite Resins - chemistry
Dental Bonding - methods
Dental caries
Dental restorative materials
Dentin
Dentin - drug effects
Dentin-Bonding Agents - chemistry
Disinfectants
Disinfectants - pharmacology
Disinfection
Disinfection & disinfectants
Disinfection - methods
Ethanol
Ethylenediaminetetraacetic acids
Humans
Lasers
Materials Testing
Pathology
Quality assessment
Quality control
Rehabilitation
Review
Sodium
Sodium hypochlorite
Success
Systematic review
Teeth
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Title Effect of Cavity Disinfectants on Dentin Bond Strength and Clinical Success of Composite Restorations-A Systematic Review of In Vitro, In Situ and Clinical Studies
URI https://www.ncbi.nlm.nih.gov/pubmed/33396354
https://www.proquest.com/docview/2475198139
https://search.proquest.com/docview/2475402432
https://pubmed.ncbi.nlm.nih.gov/PMC7794949
https://doaj.org/article/1d61a76d7e3746a897e7e71fd2fc6751
Volume 22
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