Potential Role of Selenium in the Treatment of Cancer and Viral Infections

Selenium has been extensively evaluated clinically as a chemopreventive agent with variable results depending on the type and dose of selenium used. Selenium species are now being therapeutically evaluated as modulators of drug responses rather than as directly cytotoxic agents. In addition, recent...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 23; no. 4; p. 2215
Main Authors:	Rataan, Aseel O, Geary, Sean M, Zakharia, Yousef, Rustum, Youcef M, Salem, Aliasger K
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 17-02-2022 MDPI
Subjects:	Animals Antineoplastic Agents - chemistry Antineoplastic Agents - therapeutic use cancer chemotherapy Clinical trials COVID-19 COVID-19 - drug therapy COVID-19 - virology Cytokines Cytotoxic agents Cytotoxicity DNA Repair - drug effects Drug dosages Drug resistance Drug Resistance, Neoplasm - drug effects Humans Kidney cancer Laboratory animals Lymphocytes Melanoma Metabolism Metabolites Neoplasms - drug therapy NF-E2-Related Factor 2 - chemistry NF-E2-Related Factor 2 - metabolism Patients Prostate cancer Reagents Renal cell carcinoma Review SARS-CoV-2 - drug effects SARS-CoV-2 - isolation & purification Selenium Selenium - chemistry Selenium - metabolism Selenium - pharmacology Selenium - therapeutic use Skin cancer T cell receptors Therapeutic targets Thymus gland Tumors viral infection Viral infections Vitamin E United States > US cancer viral infection drug resistance selenium chemotherapy
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