Role of Serotonin Transporter in Eye Development of Drosophila melanogaster

Serotonin transporter (SerT) in the brain is an important neurotransmitter transporter involved in mental health. However, its role in peripheral organs is poorly understood. In this study, we investigated the function of SerT in the development of the compound eye in . We found that SerT knockdown...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 21; no. 11; p. 4086
Main Authors:	Pham, Tuan L A, Binh, Tran Duy, Liu, Guanchen, Nguyen, Thanh Q C, Nguyen, Yen D H, Sahashi, Ritsuko, Men, Tran Thanh, Kamei, Kaeko
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 08-06-2020 MDPI
Subjects:	1-Phosphatidylinositol 3-kinase AKT protein Animals Antibodies Apoptosis Apoptosis - genetics Biomarkers Caspases Cell cycle Cell death Compound eye Deoxyribonucleic acid DNA Drosophila Drosophila melanogaster Drosophila melanogaster - embryology Drosophila melanogaster - genetics Drosophila melanogaster - metabolism Drosophila Proteins - genetics Drosophila Proteins - metabolism Eye - embryology eye development Gene Expression Regulation, Developmental Gene Knockdown Techniques Genotype & phenotype Insects Kinases Mental health Nervous system Neurotransmitters Organogenesis - genetics Organs Phenotype Phenotypes Phosphatidylinositol 3-Kinases - metabolism Photoreceptors PI3K/Akt pathway Proteins Proto-Oncogene Proteins c-akt - metabolism Serotonin Serotonin Plasma Membrane Transport Proteins - genetics Serotonin Plasma Membrane Transport Proteins - metabolism Serotonin transporter Signal Transduction eye development PI3K/Akt pathway cell death serotonin transporter Drosophila
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