PLGA Based Nanospheres as a Potent Macrophage-Specific Drug Delivery System

Macrophages possess an innate ability to scavenge heterogenous objects from the systemic circulation and to regulate inflammatory diseases in various organs via cytokine production. That makes them attractive targets for nanomedicine-based therapeutic approaches to inflammatory diseases. In the pres...

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Bibliographic Details
Published in:	Nanomaterials (Basel, Switzerland) Vol. 11; no. 3; p. 749
Main Authors:	Boltnarova, Barbora, Kubackova, Jana, Skoda, Josef, Stefela, Alzbeta, Smekalova, Monika, Svacinova, Petra, Pavkova, Ivona, Dittrich, Milan, Scherman, Daniel, Zbytovska, Jarmila, Pavek, Petr, Holas, Ondrej
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 16-03-2021 MDPI
Subjects:	Acids Aqueous solutions Bone marrow Cell lines Cell viability Cytokines Drug delivery Drug delivery systems Dyes Efficiency Emulsification Evaporation Fluorescent dyes Fluorescent indicators Glycolic acid IL-1β Inflammation Inflammatory diseases Lipids Macrophages Molecular structure Molecular weight mRNA Nanoparticles nanoprecipitation Nanospheres Nanotechnology Organs Pathogens PLGA Polylactide-co-glycolide Polymers Rhodamine Germany drug targeting macrophages PLGA nanoparticles inflammation liver nanospheres nanoprecipitation drug delivery hepatic disease
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