Desmoplastic fibroma of the mandible in young children—a case series

• Published in: International journal of oral and maxillofacial surgery Vol. 46; no. 2; pp. 173 - 180
• Main Authors: Khatib, B, Pogrel, M.A
• Format: Journal Article
• Language: English
• Published: Denmark Elsevier Ltd 01-02-2017
• Subjects: benign tumour of jaws; Biopsy; Child; Dentistry; desmoplastic fibroma; Diagnosis, Differential; Female; Fibroma, Desmoplastic - diagnostic imaging; Fibroma, Desmoplastic - surgery; Humans; Infant; jaw tumours in children; Male; Mandibular Neoplasms - diagnostic imaging; Mandibular Neoplasms - surgery; Reconstructive Surgical Procedures; Surgery; jaw tumours in children; desmoplastic fibroma; benign tumour of jaws
• ISSN: 0901-5027; 1399-0020
• DOI: 10.1016/j.ijom.2016.09.018

Abstract Desmoplastic fibromas are rare, benign, but aggressive lesions, affecting predominantly young people, with an affinity for the mandible. Four patients with desmoplastic fibromas of the mandible, seen between 1995 and 2015 with long-term follow-up, were identified. Three were treated by wide mandibular resection and immediate reconstruction with rib grafts, and one was treated with chemotherapy. In the three resected cases, there has been no recurrence and all rib grafts were successfully incorporated. The case treated by chemotherapy has persistence of the tumour, but it is not progressing. Desmoplastic fibromas in young children respond well to wide mandibular resection and immediate reconstruction with rib grafts. Chemotherapy may halt progression.