The human blood transcriptome exhibits time-of-day-dependent response to hypoxia: Lessons from the highest city in the world

High altitude exposes humans to hypobaric hypoxia, which induces various physiological and molecular changes. Recent studies point toward interaction between circadian rhythms and the hypoxic response, yet their human relevance is lacking. Here, we examine the effect of different high altitudes in c...

Full description

Saved in:

Bibliographic Details
Published in:	Cell reports (Cambridge) Vol. 40; no. 7; p. 111213
Main Authors:	Manella, Gal, Ezagouri, Saar, Champigneulle, Benoit, Gaucher, Jonathan, Mendelson, Monique, Lemarie, Emeline, Stauffer, Emeric, Pichon, Aurélien, Howe, Connor A., Doutreleau, Stéphane, Golik, Marina, Verges, Samuel, Asher, Gad
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 16-08-2022 Cell Press
Subjects:	CIBERSORTx circadian clocks clock genes daily rhythms high altitude humans hypoxia immune response Life Sciences lowlanders Resource whole-blood transcriptomics lowlanders hypoxia high altitude clock genes daily rhythms immune response whole-blood transcriptomics CP: Molecular biology CIBERSORTx humans circadian clocks
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!