MRA versus DSA for follow-up of coiled intracranial aneurysms: a meta-analysis

• Published in: American journal of neuroradiology : AJNR Vol. 35; no. 9; pp. 1655 - 1661
• Main Authors: van Amerongen, M J, Boogaarts, H D, de Vries, J, Verbeek, A L M, Meijer, F J A, Prokop, M, Bartels, R H M A
• Format: Journal Article
• Language: English
• Published: United States American Society of Neuroradiology 01-09-2014
• Subjects: Angiography, Digital Subtraction - methods; Embolization, Therapeutic - instrumentation; Embolization, Therapeutic - methods; Endovascular Procedures - instrumentation; Endovascular Procedures - methods; Follow-Up Studies; Humans; Intracranial Aneurysm - diagnostic imaging; Intracranial Aneurysm - therapy; Magnetic Resonance Angiography - methods; Review
• ISSN: 0195-6108; 1936-959X
• DOI: 10.3174/ajnr.a3700

MR angiography is proposed as a safer and less expensive alternative to the reference standard, DSA, in the follow-up of intracranial aneurysms treated with endovascular coil occlusion. We performed a systematic review and meta-analysis to evaluate the accuracy of TOF-MRA and contrast-enhanced MRA in detecting residual flow in the follow-up of coiled intracranial aneurysms. Literature was reviewed through the PubMed, Cochrane, and EMBASE data bases. In comparison with DSA, the sensitivity of TOF-MRA was 86% (95% CI: 82-89%), with a specificity of 84% (95% CI: 81-88%), for the detection of any recurrent flow. For contrast-enhanced MRA, the sensitivity and specificity were 86% (95% CI: 82-89%) and 89% (95% CI: 85-92%), respectively. Both TOF-MRA and contrast-enhanced MRA are shown to be highly accurate for detection of any recanalization in intracranial aneurysms treated with endovascular coil occlusion.