PMMA-based composite materials with reactive ceramic fillers: IV. Radiopacifying particles embedded in PMMA beads for acrylic bone cements

• Published in: Journal of biomedical materials research Vol. 53; no. 6; pp. 728 - 736
• Main Authors: Abboud, M., Casaubieilh, L., Morvan, F., Fontanille, M., Duguet, E.
• Format: Journal Article
• Language: English
• Published: New York John Wiley & Sons, Inc 2000; John Wiley & Sons
• Subjects: 3-(trimethoxysilyl)propylmethacrylate or γMPS; Acrylates; acrylic bone cement; Acrylics; Alumina; Aluminum Oxide; Biological and medical sciences; Biomechanics; Bone Cements; Ceramics; Compressive strength; Contrast Media; Fillers; Hardness Tests; Materials Testing; Medical sciences; Methacrylates - chemistry; microencapsulation; Organosilicon Compounds - chemistry; Particle Size; Polymerization; Polymers; Polymethyl Methacrylate; Polymethyl methacrylates; radiopaque alumina powder; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); suspension polymerization; Technology. Biomaterials. Equipments. Material. Instrumentation; Encapsulation; Property composition relationship; Methyl methacrylate polymer; Mechanical properties; Compressive strength; Surface treatment; Cement; Size effect; Radioopaque marker; Alumina; Pattern analysis; Ceramic materials; Biomedical engineering
• DOI: 10.1002/1097-4636(2000)53:6<728::AID-JBM16>3.0.CO;2-A
• EISSN: 1097-4636
• ISSN: 0021-9304

New acrylic bone cements were prepared from alumina particles previously treated by 3‐(trimethoxysilyl)propylmethacrylate (γ‐MPS) and embedded in poly(methylmethacrylate‐co‐ethylacrylate) beads with about 7 mol% of ethyl acrylate repeating units. The encapsulation was performed through a conventional suspension polymerization process. The influence of (i) the concentration of the dispersion stabilizer and (ii) the alumina content upon the shape, size, and size distribution of the acrylic beads was studied. Cements were prepared from each batch by hand‐mixing alumina‐filled acrylic beads with a liquid monomer mixture containing methyl methacrylate, n‐butyl methacrylate, and N,N‐dimethyl‐p‐toluidine. Benzoyl peroxide was previously added to the solid part. The powder‐to‐liquid ratio was equal to 2 for each formulation. Compressive strength of cured cement decreases with alumina content, whereas compressive modulus remains roughly constant. These results are in contradiction to those obtained for cements based on a mixture of γ‐MPS‐treated alumina and unfilled acrylic beads. Nevertheless, they are interpreted in terms of alumina arrangement in the cement. In the first case, alumina particles contribute to the reinforcement of the dispersed acrylic phase, with poor benefits for the whole materials. In the second case, they allow the reinforcement of the continuous acrylic phase and, therefore, the cement's one. © 2000 John Wiley & Sons, Inc. Biomed Mater Res (Appl Biomater) 53: 728–736, 2000